Eco-friendly synthesis of Chitosan NPs from Fioria vitifolia (L.) L: Potential to Antibacterial, Antioxidant, Cytotoxicity properties of HepG2 cells and their evaluation of safety on Zebrafish embryo
Results in Engineering,
Journal Year:
2025,
Volume and Issue:
unknown, P. 104076 - 104076
Published: Jan. 1, 2025
Language: Английский
Biogenic Nickel Oxide Nanoparticles: Synthesis, Characterization and Biomedical Potential
Molecular Biotechnology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 5, 2025
Language: Английский
WOUND HEALING EVALUATION OF NOVEL CISSUS QUADRANGULARIS, BIOCERAMICS AND TENDON EXTRACELLULAR MATRIX INCORPORATED SCAFFOLDS FOR PERIODONTAL BONE REGENERATION WITH ZEBRAFISH MODELS
Srinivasa Sitaram,
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Balaji Ganesh,
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Gurumoorthy Kaarthikeyan
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et al.
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY,
Journal Year:
2025,
Volume and Issue:
unknown, P. 206 - 215
Published: March 20, 2025
Background:
Wound
healing
is
a
complex
biological
process
involving,
proliferation,
and
tissue
remodelling,
requiring
advanced
biomaterials
to
facilitate
effective
regeneration.
This
study
evaluated
the
wound
potential
of
composite
scaffolds
incorporating
Cissus
quadrangularis
extract,
carrageenan,
tendon
extracellular
matrix
(ECM)
with
bioceramics
such
as
silver
hydroxyapatite
tricalcium
phosphate
using
zebrafish
model.
Materials
Methods:
The
were
extensively
characterized
Scanning
Electron
Microscopy
(SEM),
Fourier
Transform
Infrared
Spectroscopy
(FTIR),
X-
ray
diffraction
(XRD)
determine
their
physiochemical
properties
correlation
efficacy.
wild-
type
wounded
treated
following
negative
control
(Group
1),
(TEM)
2),
Group
3
(contained
+
2
components),
4
(Silver
components)
respectively
for
21
days.
closure
ratio
was
assessed
on
0,
7
14
days
histological
observations.
Results:
As
results,
SEM
analysis
revealed
highly
porous
architecture
interconnected
pores,
enhancing
cellular
adhesion,
migration
at
site.
surface
roughness
provided
an
optimal
microenvironment
fibroblast
infiltration
re-epithelization,
accelerating
process.
FTIR
confirmed
presence
hydroxyl,
carboxyl,
amide,
groups
indicating
strong
biomaterial
interactions,
hydration,
bioactivity.
observed
peaks
validated
incorporation
essential
calcium
ion
release
osteogenic
differentiation.
XRD
patterns
exhibited
well-
defined
crystalline
corresponding
bioactive
glass,
ensuring
stability,
controlled
degradation,
prolonged
bioactivity
Zebrafish
assays
demonstrated
significant
improvements
in
closure,
reduced
inflammation,
enhanced
remodelling
scaffold
groups.
histology
observations
that
treatment
induced
rapid
epidermal
formation,
immune
cell
activity,
vascularization.
Faster
contraction
new
scale
formation
post
injury,
highlighting
scaffold’s
effectiveness
compared
slower
recovery
untreated
controls.
combined
effects
synergistic
approach
Conclusion:
application
phosphate,
C.
quadrangularis,
TEM
effectively
promoted
healing.
Future
research
should
focus
optimizing
composition
validating
efficacy
mammalian
models
translational
applications
Language: Английский
Unraveling the Synergistic effects of ZnO and Ag@ZnO Nanoparticles: An in Vitro investigation of Anti-Cancer, Anti-Inflammatory, Antioxidant, and antibacterial properties
Sangeetha Alaguvel,
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Samira Khathoon Kalifathullah,
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S. Devikala
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et al.
Inorganic Chemistry Communications,
Journal Year:
2025,
Volume and Issue:
unknown, P. 114522 - 114522
Published: April 1, 2025
Language: Английский
Eco-friendly synthesis of ZnO nanoparticles fabricated using Fioria vitifolia L. and their Biomedical Potentials
Mohamed Imath,
No information about this author
Jayant Giri,
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Faruq Mohammad
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et al.
Microbial Pathogenesis,
Journal Year:
2024,
Volume and Issue:
unknown, P. 107139 - 107139
Published: Nov. 1, 2024
Language: Английский
Eco-friendly synthesis of silver nanoparticles using Phyllanthus niruri leaf extract: Assessment of antimicrobial activity, effectiveness on tropical neglected mosquito vector control, and biocompatibility using a fibroblast cell line model
K. Prabakaran,
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Mathalaimuthu Baranitharan,
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M. Mathiyazhagan
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et al.
Open Chemistry,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: Jan. 1, 2024
Abstract
Mosquitoes
are
rapidly
advancing
as
vectors
of
several
severe
diseases.
The
increasing
resistance
mosquitoes
and
the
environmental
harm
caused
by
insecticides
pose
significant
challenges
for
eradicating
mosquito
vectors.
In
this
study,
18
plant
extracts
were
tested
larvicidal
properties
against
Aedes
aegypti,
Culex
quinquefasciatus
,
Anopheles
stephensi
larvae.
Phyllanthus
niruri
(Pn)
showed
enhanced
activity
in
both
laboratory
field
trials.
biosynthesis
silver
nanoparticles
(AgNPs)
using
Pn
leaf
methanol
extract
(Pn-LME)
was
confirmed
UV-visible
spectroscopy,
X-ray
diffraction,
transmission
electron
microscopy,
scanning
Fourier-transform
infrared
spectroscopy.
Among
various
concentrations,
3
mM
AgNPs
exhibited
LC90
values
0.83,
1.46,
9.11
ppm
compared
to
9.25,
93.48,
14.60
Pn-LME
A.
C.
aegypti
respectively.
This
indicates
high
mortality
at
low
AgNP
concentrations.
Additionally,
Pn-AgNPs
antibacterial
no
cytotoxicity
normal
fibroblast
cells
(L929).
Field
trials
demonstrated
a
98.70%
decrease
larval
density
breeding
sites,
96.55%
reduction
97.85%
Ae.
sites.
study
presents
an
eco-friendly
cost-effective
bio-pesticide
synthesized
from
leaves
controlling
preventing
filarial,
dengue,
malaria
Language: Английский
Eco-friendly synthesis of betanin-conjugated zinc oxide nanoparticles: antimicrobial efficacy and apoptotic pathway activation in oral cancer cells
Molecular Biology Reports,
Journal Year:
2024,
Volume and Issue:
51(1)
Published: Nov. 7, 2024
Language: Английский
Green synthesis of silver nanoparticles using Trema Orientalis (L.) extract and evaluation of their antibacterial activity
Richa Das,
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Pradeep Kumar,
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Amit Kumar Singh
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et al.
Green Chemistry Letters and Reviews,
Journal Year:
2024,
Volume and Issue:
18(1)
Published: Dec. 23, 2024
A
novel
green
method
was
developed
to
create
pure,
safe,
and
stable
silver
nanoparticles
(AgNPs)
using
Trema
orientalis
(L.)
leaf
extract
as
a
reducing
stabilizing
agent
evaluated
its
antibacterial
activity.
UV-vis
spectroscopy
indicated
the
biogenesis
of
AgNPs
based
on
absorbance
in
range
400–500
nm.
The
Fourier
transform
infrared
(FTIR)
revealed
that
flavonoids
play
crucial
role
synthesis
stability
AgNPs,
serving
primary
phytoconstituents
involved.
were
spherical,
crystalline
nature.
size
ranged
from
14.04–34.38
nm
determined
by
transmission
electron
microscopy
(TEM).
For
phase
determination
structure,
subjected
X-ray
diffraction
(XRD).
crystallinity
percentage
calculated
79.28%.
investigation
atomic
force
(AFM)
measured
average
roughness,
maximum
height,
valley
depth
AgNPs.
mean
surface
roughness
12.054
well
diffusion
demonstrated
activity
against
Staphylococcus
aureus,
resulting
inhibition
zones
measuring
9
,
10
13
14
mm.
These
effects
observed
at
concentrations
25
µg/mL,
50
75
100
respectively.
minimum
inhibitory
concentration
S.
aureus
55.31
μg/ml.
This
work
provides
more
sustainable
efficient
bacterial
treatment.
Language: Английский