How Stem and Progenitor Cells Can Affect Renal Diseases DOI Creative Commons
Francesca Montenegro, Francesca Giannuzzi, Angela Picerno

et al.

Cells, Journal Year: 2024, Volume and Issue: 13(17), P. 1460 - 1460

Published: Aug. 30, 2024

Stem and progenitor cells have been observed to contribute regenerative processes in acute renal failure chronic kidney disease. Recent research has delved into the intricate mechanisms by which stem exert their influence on diseases. Understanding how these integrate with existing architecture response injury could pave way for innovative treatment strategies aimed at promoting repair regeneration. Overall, role of diseases is multifaceted, ability tissue regeneration, immune modulation, maintenance homeostasis. Here, we review studies that available today about involvement both therapies causes diseases, as well natural healing mechanisms, taking account main disorders, such IgA nephropathy, lupus nephritis, diabetic C3 glomerulopathy, focal segmental glomerulosclerosis, idiopathic membranous anti-glomerular basement membrane glomerulonephritis, ANCA-associated crescentic glomerulonephritis. Moreover, based comprehensive data framework specific progenitors, hypothesize a possible adult progenitors exacerbating or recovering illness.

Language: Английский

Potential biomarkers of recurrent FSGS: a review DOI Creative Commons
Shuang Hou,

Bo Yang,

Qian Chen

et al.

BMC Nephrology, Journal Year: 2024, Volume and Issue: 25(1)

Published: Aug. 12, 2024

Focal segmental glomerulosclerosis (FSGS), a clinicopathological condition characterized by nephrotic-range proteinuria, has high risk of progression to end-stage renal disease (ESRD). Meanwhile, the recurrence FSGS after transplantation is one main causes graft loss. The diagnosis recurrent mainly based on puncture biopsy transplants, an approach not widely consented patients with early mild disease. Therefore, there urgent need find definitive diagnostic markers that can act as target for and intervention in treatment patients. In this review, we summarize domestic international studies pathophysiology, pathogenesis earliest screening methods describe functions roles specific circulating factors FSGS, order provide new theoretical basis recurrence, well aid exploration therapeutic targets.

Language: Английский

Citations

3
How Stem and Progenitor Cells Can Affect Renal Diseases DOI Creative Commons
Francesca Montenegro, Francesca Giannuzzi, Angela Picerno

et al.

Cells, Journal Year: 2024, Volume and Issue: 13(17), P. 1460 - 1460

Published: Aug. 30, 2024

Stem and progenitor cells have been observed to contribute regenerative processes in acute renal failure chronic kidney disease. Recent research has delved into the intricate mechanisms by which stem exert their influence on diseases. Understanding how these integrate with existing architecture response injury could pave way for innovative treatment strategies aimed at promoting repair regeneration. Overall, role of diseases is multifaceted, ability tissue regeneration, immune modulation, maintenance homeostasis. Here, we review studies that available today about involvement both therapies causes diseases, as well natural healing mechanisms, taking account main disorders, such IgA nephropathy, lupus nephritis, diabetic C3 glomerulopathy, focal segmental glomerulosclerosis, idiopathic membranous anti-glomerular basement membrane glomerulonephritis, ANCA-associated crescentic glomerulonephritis. Moreover, based comprehensive data framework specific progenitors, hypothesize a possible adult progenitors exacerbating or recovering illness.

Language: Английский

Citations

1