Teen Pregnancy and Risk of Premature Mortality

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(3), P. e241833 - e241833

Published: March 14, 2024

Importance Unintentional injury, suicide, and homicide are leading causes of death among young females. Teen pregnancy may be a marker adverse life experiences. Objective To evaluate the risk premature mortality from 12 years age onward in association with number teen pregnancies at pregnancy. Design, Setting, Participants This population-based cohort study was conducted all females alive April 1, 1991, to March 31, 2021, Ontario, Canada (the most populous province, which has universal health care data collection). The period ended 2022. Exposures main exposure between 19 (0, or ≥2). Secondary exposures included how (birth miscarriage vs induced abortion) first Main Outcomes Measures outcome all-cause starting age. Hazard ratios (HRs) were adjusted for year birth, comorbidities 9 11 age, area-level education, income level, rurality. Results Of 2 242 929 teenagers, 163 124 (7.3%) experienced median 18 (IQR, 17-19 years). those pregnancy, 60 037 (36.8%) birth (of 59 485 [99.1%] live births), 106 135 (65.1%) abortion. end follow-up 25 18-32 years) without 31 25-36 There 6030 deaths (1.9 per 10 000 person-years [95% CI, 1.9-2.0 person-years]) 701 (4.1 3.8-4.5 1 345 (6.1 5.5-6.8 more pregnancies; HRs (AHRs) 1.51 (95% 1.39-1.63) 2.14 1.92-2.39) pregnancies. Comparing AHR 1.25 1.12-1.40) noninjury, 2.06 1.75-2.43) unintentional 2.02 1.54-2.65) intentional injury. Conclusions Relevance In this 2.2 million female associated future mortality. It should assessed whether supports teenagers who experience can enhance prevention subsequent middle adulthood.

Language: Английский

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The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis

BMC Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: Aug. 15, 2024

Abstract Background Adverse childhood experiences (ACEs) have been implicated in the aetiology of a range health outcomes, including multimorbidity. In this systematic review and meta-analysis, we aimed to identify, synthesise, quantify current evidence linking ACEs Methods We searched seven databases from inception 20 July 2023: APA PsycNET, CINAHL Plus, Cochrane CENTRAL, Embase, MEDLINE, Scopus, Web Science. selected studies investigating adverse events occurring during (< 18 years) an assessment multimorbidity adulthood (≥ years). Studies that only assessed or outcomes children were excluded. Risk bias was using ROBINS-E tool. Meta-analysis prevalence dose–response meta-analysis methods used for quantitative data synthesis. This pre-registered with PROSPERO (CRD42023389528). Results From 15,586 records, 25 eligible inclusion (total participants = 372,162). The exposure ≥ 1 48.1% (95% CI 33.4 63.1%). 34.5% 23.4 47.5%). Eight provided sufficient 197,981). There significant dose-dependent relationship between ACE ( p < 0.001), every additional contributing 12.9% 7.9 17.9%) increase odds However, there heterogeneity among included I 2 76.9%, Cochran Q 102, 0.001). Conclusions is first synthesise literature on multimorbidity, showing across large number participants. It consolidates enhances extensive body shows association individual long-term conditions, risky behaviours, other poor outcomes.

Language: Английский

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Patterns of Adverse Childhood Experiences and Neurocognitive Development

JAMA Pediatrics, Journal Year: 2024, Volume and Issue: 178(7), P. 678 - 678

Published: May 28, 2024

Importance Early life adversity is associated with higher risk of many adult health problems, including mental illness, substance abuse, suicide attempt, and chronic diseases. Many previous studies investigated adversities one at a time or the toll cumulative number adversities. Objective To examine co-occurrence among children how specific patterns are neurocognitive development. Design, Setting, Participants This cohort study used data from Collaborative Perinatal Project (CPP), which enrolled national sample women during pregnancy followed their offspring to ages 7 8 years, between 1959 1974. The CPP was community-based conducted in 12 US medical centers. ascertained through prenatal clinics diverse respect race socioeconomic status. Data analysis performed August 2023 March 2024. Exposures A latent class adverse childhood experiences that occurred birth years identify common Main Outcomes Measures Five tests were measure children’s visual-motor, sensory-motor, auditory-vocal, intelligence quotient, academic skills. Results included 49 853 (25 226 boys [50.6%]); 24 436 (49.0%) had low probability experiencing any adversity, whereas remaining half classified into 5 groups reflecting distinct adversities: parental harshness neglect, 1625 (3.3%); separation poverty, 8731 (17.5%); family instability, 3655 (7.3%); loss, 1505 (3.0%); crowded housing 9901 (19.9%). Children 4 these lower scores than standardized mean differences ranging −0.07 (95% CI, −0.11 −0.03) −0.86 −1.06 −0.65). Conclusions Relevance These findings suggest deficits functions. It important understand complexity exposure resulting developmental consequences, as well underlying mechanisms, help support exposed foster healthier resilient trajectories

Language: Английский

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A Scoping Review on Adverse Childhood Experiences Studies Using Latent Class Analysis: Strengths and Challenges

Trauma Violence & Abuse, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 18, 2023

Adverse childhood experiences (ACEs) studies reveal the profound impacts of experiencing trauma and hardships in childhood. However, cumulative risk approach treating ACEs obscures heterogeneity their consequences, making actionable interventions impossible. latent class analysis (LCA) has increasingly been used to address these concerns by identifying underlying subgroups people who experience distinctive patterns co-occurring ACEs. Though LCA its strengths, existing research produces few comparable findings because results are dependent on measures indicators, which vary widely study. Therefore, a scoping review using that focuses measures, is needed inform field. Following Arksey O'Malley's five-stage methodological framework, we first identified 211 articles from databases EBSCOhost, PubMed, Scopus "adverse experiences" for title search "latent analysis" abstract search. Based inclusion criteria peer-reviewed written English published 2012 2022 exclusion nonempirical not analyzing ACEs, finally selected 58 this review. Results showed endorsed community examine associations between human health well-being across culturally diverse populations. overcame limitations traditional methods revealing specific clusters exert potent effects certain outcomes. arbitrary nature selecting limited use theory impedes field moving forward.

Language: Английский

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Association of adverse and positive childhood experiences with health-related quality of life in adolescents

Public Health, Journal Year: 2024, Volume and Issue: 228, P. 92 - 99

Published: Feb. 10, 2024

Language: Английский

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Intervening After Trauma: Child–Parent Psychotherapy Treatment Is Associated With Lower Pediatric Epigenetic Age Acceleration

Psychological Science, Journal Year: 2024, Volume and Issue: 35(9), P. 1062 - 1073

Published: Aug. 14, 2024

Early-life adversity increases the risk of health problems. Interventions supporting protective and responsive caregiving offer a promising approach to attenuating adversity-induced changes in stress-sensitive biomarkers. This study tested whether participation an evidence-based dyadic psychosocial intervention, child-parent psychotherapy (CPP), was related lower epigenetic age acceleration, trauma-sensitive biomarker accelerated biological aging that is associated with later impairment, sample children trauma histories. Within this quasi-experimental, repeated-measures study, we examined acceleration at baseline postintervention low-income receiving CPP treatment (

Language: Английский

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Optimising Access to Healthcare for Patients Experiencing Homelessness in Hospital Emergency Departments

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(3), P. 2424 - 2424

Published: Jan. 30, 2023

The ED is often the first and sometimes only place where people experiencing homelessness seek medical assistance. While access to primary healthcare a preferable more cost-effective alternative ED, for many reasons, are much less likely have regular General Practitioner compared those living in stable accommodation. Drawing on growing body of emergency care literature practice, we synthesised four potential interventions optimise when present an ED. Although EDs no way responsible resolving complex health social issues their local homeless population, they common contact point therefore opportunity improve healthcare.

Language: Английский

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Impact of adverse childhood experiences on sensory thresholds in adults living with multimorbidity and chronic pain (the ACE-MAP study): protocol for an observational feasibility study

BMJ Open, Journal Year: 2025, Volume and Issue: 15(1), P. e091053 - e091053

Published: Jan. 1, 2025

Introduction Exposure to adverse childhood experiences (ACEs) is associated with a range of poor long-term health outcomes, including multimorbidity and chronic pain. Epidemiological evidence underpins much this relationship; however, psychophysical testing methods, such as quantitative sensory (QST), may provide valuable insights into potential mechanisms. Previous studies have shown inconsistent links between ACEs QST, but the QST profiles people not been reported. We hypothesise that exposure lowered thresholds (ie, experience pain milder stimuli) association stronger in adults and/or The ACE-MAP study cross-sectional feasibility primary aim assessing acceptability proposed procedures. secondary generate preliminary data understand impact on thresholds. Methods analysis plan recruit 40 participants, 10 each following groups: (1) multimorbidity; (2) without (3) pain; (4) controls. Participants will complete series questionnaires (including ACEs, conditions) then take part assessments. outcomes include measures design. exploratory relationship Ethics dissemination was approved by Scotland B Research Committee (reference: 24/SS/0031). Results from be presented at scientific conferences, published peer-reviewed journal shared patients members public through other media streams. Trial registration number ISRCTN10049430 .

Language: Английский

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The Consequences of Abuse, Neglect and Cyber-bullying on the Wellbeing of the Young

Published: Feb. 1, 2024

Using cross-sectional data files for the United States we show that difficulties experienced in childhood -so-called Adverse Child Experiences (ACE)s -are strongly and significantly associated with mental health adulthood.Our evidence is taken from eight Behavioral Risk Factor Surveillance System (BRFSS) surveys 2009-2023 which contain a special supplement asking respondents to recall abuse their childhood.We find poor on rise States, particularly among young women.This upward trend also apparent National Health Interview Surveys 1997-2021, Healthy Minds of 2007-2023 Youth Behavior (YRBSS) high school students.We ACEs are correlated both older people effect additive.The impact living household member large relative other pronounced younger people.Being bullied, including electronically, negatively wellbeing students.Time spent front screen has been rising over time an independent negative above bullying, one more women.

Language: Английский

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Adverse childhood experiences and health outcomes: a 20-year real-world study

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 7, 2025

Adverse childhood experiences (ACEs) refer to traumatic life events occurred in that comprise abuse (e.g., psychological, physical, sexual), neglect (psychological and physical), indirect violence or household dysfunctions. Such ultimately lead severe short-, medium- long-term consequences for the victim's health. The goal of this study is analyze prevalence health outcomes children <16 years age, who were suspected ACEs by physicians. specific objectives consist analyzing 3 outcome groups: (a) injuries intoxications; (b) mental disorders; (c) physical disorders. We performed a real-world, retrospective, observational, cross-sectional, multicentric study, using complementary data from electronic records healthcare registries local unit Matosinhos, generated between January 1, 2001, December 31, 2021 (total child population observed during period=40 536). Keywords ICD-9, ICD-10, ICPC-2 codes applied find on victims. Just over 2% referred as victims available information (n=918). Social problems, intoxications, disorders, disorders at higher percentages than total analyzed population. These results reveal may be underdiagnosed, which, given aforementioned (and described literature) their current future health, should taken critical warning professionals. Detections reports are fundamental early treatment, aiming avoid an escalation damage prevent re-victimization.

Language: Английский

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