Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries

Vaccines, Journal Year: 2023, Volume and Issue: 12(1), P. 34 - 34

Published: Dec. 28, 2023

Mass vaccination against COVID-19 is the best method to ensure herd immunity in order curb effect of pandemic on global economy. It therefore important assess determinants vaccine acceptance and hesitancy a scale. Factors were recorded from cross-sectional studies analyzed with t-Test, ANOVA, correlation, meta-regression analyses synthesized identify trends inform policy. We registered protocol (ID: CRD42022350418) used standard Cochrane methods PRISMA guidelines collect synthesize articles published between January 2020 August 2023. A total 67 576 185 countries involving 3081,766 participants included this synthesis. Global was 65.27% (95% CI; 62.72–67.84%), while stood at 32.1% 29.05–35.17%). One-Way ANOVA showed that there no significant difference percentage Gross Domestic Product spent procurement across World Bank income levels (p < 0.187). There 0.001) 0.005) different Income levels. level had strong influence 0.0004) 0.003) but did not. correlation (r = −0.11, p 0.164) or −0.09, 0.234). Meta-regression analysis living an urban setting (OR 4.83, 95% 0.67–212.8), rural 2.53, 0.29–119.33), older 1.98, 0.99–4.07), higher education 1.76, 0.85–3.81), being low earner 2.85, 0.45–30.63) increased odds high acceptance. influenza 33.06, 5.03–1395.01), mistrust for vaccines 3.91, 1.92–8.24), complacency 2.86, 1.02–8.83), pregnancy 2.3, 0.12–141.76), taking traditional herbs 2.15, 0.52–10.42), female 1.53, 0.78–3.01), safety concerns 1.29, 0.67–2.51). proposed number recommendations increase COVID-19.

Language: Английский

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Anti-SARS-CoV-2 Antibodies Level and COVID-19 Vaccine Boosters among Healthcare Workers with the Highest SARS-CoV-2 Infection Risk—Follow Up Study

Vaccines, Journal Year: 2024, Volume and Issue: 12(5), P. 475 - 475

Published: April 29, 2024

During the COVID-19 pandemic, several vaccines were developed to limit spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, due SARS-CoV-2 mutations and uneven vaccination coverage among populations, a series waves have been caused by different variants concern (VOCs). Despite updated vaccine formulations for new VOC, benefits additional doses raised many doubts, even high-risk groups such as healthcare workers (HCWs). We examined factors underlying hesitancy receive booster analysed anti-SARS-CoV-2 IgG antibody response after HCWs. Our study found that 42% HCWs hesitant about second dose, while 7% reported no intent get vaccinated with any doses. As reasons not vaccinating, participants most frequently highlighted lack time, negative experiences previous vaccinations, immunity conferred past infections. In addition, we lowest post-vaccination titres who did dose highest two

Language: Английский

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Vaccine Hesitancy, Knowledge, and COVID-19 Vaccination in a Sample of Italian and Albanian Healthcare Students Attending an University in Albania

Tropical Medicine and Infectious Disease, Journal Year: 2024, Volume and Issue: 9(3), P. 57 - 57

Published: Feb. 29, 2024

Vaccine hesitancy (VH) has increased over the past decade with large geographical variations between countries, posing a threat to global public health. This phenomenon is growing in general population as well among healthcare workers (HCWs), who are most reliable source of vaccine-related information for patients. Special attention must therefore be paid medical students, future HCWs. We conducted cross-sectional study (November 2022-January 2023) on all Albanian and Italian students attending science courses at Catholic University "Our Lady Good Counsel" (Tirane, Albania) investigate VH factors contributing it (using Vaccination Attitude Examination Scale-VAX), including COVID-19 vaccination. knowledge was assessed using Zingg Siegrist Scale. Students were asked voluntarily answer an anonymous questionnaire. 689 questionnaires collected (58.8% Albanians, 72.3% female; 70.4% aged 20-25 years; Medicine Surgery course). Generally, showed low VH, especially Italians (p < 0.001); however, some observed regarding potential long-term effects vaccines, Albanians 0.05). The results also significant difference vaccine scores different course years (χ2 = 90.058; df 40; p 0.001) degree 89.932; 0.001). With regard vaccination, being origin significantly increases risk not vaccinated (OR 7.215; 95%CI 3.816-13.640, 0.001), highlighting possible differences coverage policy two countries. should addressed early stages during sciences courses, order protect workers, preserve essential health services, reduce further pandemics.

Language: Английский

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Factors affecting the intention of healthcare workers and students to receive COVID-19 booster dose vaccination: a systematic review

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 6, 2024

Abstract Background The COVID-19 pandemic has caused an unprecedented health, social and economic crisis worldwide, as the SARS-CoV-2 virus managed to cause a major threat with significant morbidity mortality in certain population groups. risk of is exacerbated by its easy transmission continued spread, despite multilevel interventions, extensive containment measures vaccination. Vaccine hesitancy refers person’s reluctance, delay accepting or even refusing be vaccinated available vaccination services. Objective To investigate factors that influence health professionals students sciences accept, not, booster dose vaccine. Sub-objectives were assess vaccine hesitancy, specifically those doses, presentation views attitudes above Methods relevant bibliography was searched electronically scientific databases such PubMed, Embase, Cochrane Library Scopus until August 2023. main selection criteria mainly descriptive studies, published English Greek. subjects human over 18 years old. time frame this search last four years. Results From results systematic review, it shown many different intention both healthcare workers students, well general population, accept At same time, countries continents -that studied- present diverse socio-demographic characteristics their willingness, vaccinated. Conclusions doses offer further immunity reduce severe impacts disease, hospitalization death. Since play critical role shaping local communities’ towards vaccines, beliefs crucial role. For reason, recommended training via competent institutions, mobilize sensitize them, order base on evidence-based practice. As new technologies policies are built around ongoing testing effectiveness, updated guidelines according group proven vital impact disease. Further future studies necessary.

Language: Английский

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Future COVID-19 Booster Vaccine Refusal in Healthcare Workers after a Massive Breakthrough Infection Wave, a Nationwide Survey-Based Study

Vaccines, Journal Year: 2023, Volume and Issue: 11(5), P. 987 - 987

Published: May 16, 2023

Background: An unprecedented coronavirus disease 2019 (COVID-19) wave occurred in China between December 2022 and January 2023, challenging the efficacy of primary series COVID-19 vaccines. The attitudes toward future booster vaccines (CBV) after massive breakthrough infection among healthcare workers remain unknown. This study aimed to explore prevalence determinants CBV refusal workers. Methods: Between 9 19 February a cross-sectional nationwide online survey was conducted using self-administered questionnaire vaccine China. Sociodemographics, profession, presence chronic medical conditions, previous infection, towards CBV, reasons for were collected. We estimated odds ratio [OR] with 95% confidence interval [CI] multivariable logistic regression model factors associated refusal. Results: Among 1618 participants who completed survey, 1511 respondents two or more doses analyzed. A total 648 (41.8%) unwilling receive CBV. Multivariable analysis revealed association profession (vs. other staff, physician-adjusted OR 1.17, 95%CI 0.79–1.72, nurse-adjusted 1.88, 1.24−2.85, p = 0.008), history allergy (adjusted 1.72, 1.05–2.83, 0.032), lower self-perceived risk (p < 0.001), belief effectiveness 0.014), safety necessities public 0.001, respectively). Conclusions: Our findings highlight that considerable proportion against dose an wave. Self-perception risk, potential harm doubtful are main determinants. may help health authorities establish vaccination programs.

Language: Английский

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SARS-CoV-2 seroprevalence and antibody trajectories after easing of COVID-19 restrictions: a longitudinal study in China

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 3, 2024

We aimed to evaluate the seroprevalence of SARS-CoV-2 and investigate trajectories protective immunity associated risk factors in eastern China between March November 2023 after easing COVID-19 restrictions.

Language: Английский

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Primary series and booster COVID-19 vaccine effectiveness in a cohort of healthcare workers in Albania during a BA.1 and BA.2 variant period, January – May 2022

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: May 5, 2023

Abstract Background Healthcare workers (HCWs) have experienced high rates of COVID-19 morbidity and mortality. We estimated two-dose primary series monovalent booster vaccine effectiveness (VE) against symptomatic SARS-CoV-2 Omicron (BA.1 BA.2) infection among HCWs in three Albanian hospitals during January–May 2022. Methods Study participants completed weekly symptom questionnaires, underwent PCR testing when symptomatic, provided quarterly blood samples for serology. VE using Cox regression models (1-hazard ratio), with vaccination status as the time-varying exposure unvaccinated reference group, adjusting potential confounders: age, sex, prior (detected by PCR, rapid-antigen test or serology), household size. Results At start analysis period, 76% 1,462 had received a series, 10% dose, 9% were unvaccinated; 1,307 (89%) evidence infection. Overall, 86% 98% doses BNT162b2. The median time interval from second dose to period was 289 days (IQR:210– 292) 30 (IQR:22–46), respectively. PCR-confirmed 34% (95%CI: -36;68) 88% 38;98) booster. Conclusions Among HCWs, most whom been previously infected, offered improved BA.1 BA.2 circulation. Our findings support promoting uptake which, January 2023, only 20%.

Language: Английский

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Primary Series and Booster Coronavirus Disease 2019 Vaccine Effectiveness in a Cohort of Healthcare Workers in Albania During a BA.1 and BA.2 Variant Period, January–May 2022

Open Forum Infectious Diseases, Journal Year: 2023, Volume and Issue: 10(10)

Published: Sept. 30, 2023

Abstract Background Healthcare workers (HCWs) have experienced high rates of coronavirus disease 2019 (COVID-19) morbidity and mortality. We estimated COVID-19 2-dose primary series monovalent booster vaccine effectiveness (VE) against symptomatic severe acute respiratory syndrome 2 (SARS-CoV-2) Omicron (BA.1 BA.2) infection among HCWs in 3 Albanian hospitals during January–May 2022. Methods Study participants completed weekly symptom questionnaires, underwent polymerase chain reaction (PCR) testing when symptomatic, provided quarterly blood samples for serology. VE using Cox regression models (1 – hazard ratio), with vaccination status as the time-varying exposure unvaccinated reference group, adjusting potential confounders: age, sex, prior SARS-CoV-2 (detected by PCR, rapid antigen test, or serology), household size. Results At start analysis period, 76% 1462 had received a series, 10% dose, 9% were unvaccinated; 1307 (89%) evidence infection. Overall, 86% 98% doses BNT162b2. The median time interval from second dose to period was 289 (interquartile range [IQR], 210–292) days 30 (IQR, 22–46) days, respectively. PCR-confirmed 34% (95% confidence [CI], −36% 68%) 88% CI, 39%–98%) booster. Conclusions Among HCWs, most whom been previously infected, offered improved BA.1 BA.2 circulation. Our findings support promoting uptake which, January 2023, only 20%. Clinical Trials Registration. NCT04811391.

Language: Английский

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Attitude of Healthcare Workers towards COVID-19 Vaccination at a University Hospital

Klimik Dergisi/Klimik Journal, Journal Year: 2023, Volume and Issue: 36(4), P. 239 - 245

Published: Dec. 29, 2023

Amaç:

Language: Английский

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Factors Driving the Attitudes and Hesitancy of Albanian Parents toward COVID-19 Vaccination of Children

Published: Dec. 1, 2023

In June 2022, the Food and Drug Administration (FDA) authorized use of Moderna Pfizer-BioNTech COVID-19 mRNA vaccines for children aged 6 months–4 years in United States. Vaccine hesitancy is context-, time-, place-, vaccine-specific. This study aims to analyze different factors influencing perceptions attitudes Albanian parents toward vaccination children. The anti-COVID-19 vaccine remains unapproved younger than 12 Albania. A validated questionnaire composed 33 elements was used purpose this study. total 600 parents/caregivers responded questionnaire. negative their child were linked mild forms disease faced by fear adverse events.

Language: Английский

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