Removal, fate, and bioavailability of fluoroquinolone antibiotics in a phytoremediation system with four wetland plants: Combing dynamic DGT and traditional methods

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 881, P. 163464 - 163464

Published: April 14, 2023

Language: Английский

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In vitro determination of probiotic efficacy of Bacillus subtilis TLDK301120C24 isolated from tilapia against warm water fish pathogens and in vivo validation using gnotobiotic zebrafish model

Microbial Pathogenesis, Journal Year: 2023, Volume and Issue: 185, P. 106429 - 106429

Published: Nov. 7, 2023

Language: Английский

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Spatiotemporal dynamics, bioaccumulation, and critical influencing factors of antibiotics in tilapia aquaculture: A study on source identification and environmental fate within typical farming systems

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 477, P. 135328 - 135328

Published: July 26, 2024

Language: Английский

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Antibiotics in surface waters of the south Caspian Sea: Occurrence, spatial distribution and ecological risks

Environmental Research, Journal Year: 2024, Volume and Issue: 261, P. 119709 - 119709

Published: July 30, 2024

Language: Английский

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Unraveling the pharmaceutical footprint and risks of combining different aquaculture modes and tailwater treatment systems

Aquaculture, Journal Year: 2024, Volume and Issue: 596, P. 741763 - 741763

Published: Oct. 18, 2024

Language: Английский

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Effects of alginate oligosaccharides on the growth performance, hepatocyte health, and intestinal inflammation of the Chinese sea bass (Lateolabrax maculatus)

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100658 - 100658

Published: Jan. 1, 2025

Language: Английский

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Environmental antibiotic emissions and their residual impact on livestock farming

Molecular & Cellular Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Language: Английский

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The Effect of Oxytetracycline on the Immune Response and Expression of Immune‐Related Genes in European Sea Bass (Dicentrarchus labrax, L. 1758)

Aquaculture Research, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Antibiotics are extensively used in aquaculture to treat and prevent bacterial diseases, but their application can lead negative side effects such as immunosuppression. Oxytetracycline (OTC) is a widely antibiotic for treating diseases due its broad‐spectrum activity economic advantage. This study appraises the of OTC treatment on immune response European sea bass ( Dicentrarchus labrax , L. 1758) by assessing immune‐related gene expression, serological parameters, hematological histological findings. Fish were divided into three groups: control (fed with nonsupplemented OTC), 75 mg kg −1 day feed, 100 feed 21 days. Blood tissue samples collected analysis 4th, 7th, 10th, 14th, 21st feeding. The results showed decrease parameters nitro blue tetrazolium (NBT) positive cell, total white blood cells (WBCs), serum lysozyme activity, Ig‐M levels, complement OTC‐fed fish, while genes Lys-g Ig-M interleukin IL )‐ 1β C3 major histocompatibility complex [ MHC ] –IIα ) significantly downregulated kidney spleen tissues, especially prolonged exposure. hypothesized that long‐term use antibiotics fish disrupts functioning system. As result study, hypothesis was confirmed, using longer than normal period or high doses caused changes system made more susceptible other pathogens.

Language: Английский

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Enhanced Detection of Enrofloxacin in Seawater Using a Newly Selected Aptamer on a Graphite Oxide-Based Biosensor

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

Developing aptasensors offers several advantages including sensitivity, selectivity, cost-effectiveness, and speed over traditional analytical techniques for antibiotic detection. We have successfully identified Enro_ap3, a 30-mer enrofloxacin-binding aptamer with micromolar binding affinity, through an optimized Capture-SELEX platform. Compared to other reported aptamers, this shorter not only streamlines the design process but also eliminates common issue of strong nonspecific GO surface, thereby improving overall detection capabilities biosensor (GO-Enro_ap3-FAM). This aptasensor demonstrated remarkable selectivity by effectively distinguishing enrofloxacin from different structurally diverse antibiotics. The sensor boasts LOD 32.15 μg/mL, 2.5 times more sensitive than original 30-mer, recoveries 74%-92% relative standard deviations 6.3%-12.5% in seawater samples spiked enrofloxacin. Furthermore, aptasensor's were found be on par LC-MS/MS techniques, exhibiting no significant differences recovery rates even complex matrices. sensor's performance remained consistent across variations salinity, acidity, total organic carbon concentrations collected locations, underlining its robustness environmental conditions suitability real-world monitoring applications. Our findings highlight importance aptamer's chain length affinity toward target after immobilization substrate. These factors significantly impact seawater. Overall, provides well-balanced approach, combining adaptability, practical usability detecting pharmaceutical contaminants, such as antibiotics, marine environments.

Language: Английский

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Exogenous NADH promotes the bactericidal effect of aminoglycoside antibiotics against Edwardsiella tarda

Virulence, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 17, 2024

The global surge in multidrug-resistant bacteria owing to antibiotic misuse and overuse poses considerable risks human animal health. With existing antibiotics losing their effectiveness the protracted process of developing new antibiotics, urgent alternatives are imperative curb disease spread. Notably, improving bactericidal effect by using non-antibiotic substances has emerged as a viable strategy. Although reduced nicotinamide adenine dinucleotide (NADH) may play crucial role regulating bacterial resistance, studies examining how change metabolic profile resistance following exogenous administration scarce. Therefore, this study aimed elucidate changes that occur Edwardsiella tarda (E. tarda), which exhibits various addition NADH metabolomics. effects these alterations on activity neomycin were investigated. enhanced aminoglycoside against E. ATCC15947, achieving eradication at low doses. Metabolomic analysis revealed reprogrammed ATCC15947 promoting purine metabolism energy metabolism, yielding increased adenosine triphosphate (ATP) levels. Increased ATP levels played enhancing neomycin. Moreover, promoted efficacy tetracyclines chloramphenicols. combination with was effective other clinically resistant bacteria, including Aeromonas hydrophila, Vibrio parahaemolyticus, methicillin-resistant Staphylococcus aureus, Listeria monocytogenes. These results facilitate development approaches for preventing managing tarda–induced infections multidrug aquaculture clinical settings.

Language: Английский

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