Palladium-Catalyzed Acetoxylation of γ-Dehydro-aryl-himachalene: The Synthesis of a Novel Allylic Acetoxylated Sesquiterpene and a π-Allyl Palladium(II) Complex DOI Creative Commons

Issam Louchachha,

Abdelmajid Faris,

Youssef Edder

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(21), P. 5040 - 5040

Published: Oct. 25, 2024

Allylic oxygenated derivatives of himachalenes are highly valued molecules due to their potential applications in perfumery, cosmetics, and pharmaceuticals. Previous attempts at catalyzed allylic oxidation led the formation a very stable η

Language: Английский

Experimental Investigation and Theoretical Modeling of Copper Corrosion Inhibition by Urginea maritima Essential Oil DOI
Khaoula Mzioud, Amar Habsaoui, Sara Rached

et al.

Materials Today Sustainability, Journal Year: 2024, Volume and Issue: 27, P. 100906 - 100906

Published: July 11, 2024

Language: Английский

Citations

11
Study on the Corrosion Inhibition of E24 Steel in Acidic Medium by 1,4-benzoxazine Derivatives: An Approach Combining Chemistry, Electrochemistry, and Theoretical Modeling DOI

Saliha Loughmari,

Hassan Haddouchy,

Abdelkarim Ait Mansour

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141545 - 141545

Published: Jan. 1, 2025

Language: Английский

Citations

1
Synthesis of novel thiazole derivatives and their assessment as efficient corrosion inhibitors on mild steel in acidic medium DOI

Rashmi Sehrawat,

Sidhant Yadav,

Rashmi Pundeer

et al.

Progress in Organic Coatings, Journal Year: 2025, Volume and Issue: 203, P. 109156 - 109156

Published: Feb. 25, 2025

Language: Английский

Citations

1
Design of novel dibenzalacetone-based organic inhibitor responsible for excellent corrosion performance: Electrochemical response and theoretical exploration DOI

M’bark Elhaid,

E. Ech–chihbi, Ayoub Mouhib

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: 176, P. 114236 - 114236

Published: March 5, 2025

Language: Английский

Citations

1
Synthesis, characterization, theoretical, and evaluation of eco-friendly phenytoin-based corrosion inhibitors for mild steel DOI
Walid Ettahiri, Abderrazzak El Moutaouakil Ala Allah,

Jamila Lazrak

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: unknown, P. 135816 - 135816

Published: Nov. 1, 2024

Language: Английский

Citations

6
Inhibition of carbohydrate digestive enzymes by a complementary essential oil blend: in silico and mixture design approaches DOI Creative Commons
El Hassania Loukili, Mouhcine Fadil, Amal Elrherabi

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: March 10, 2025

Background The increasing demand for natural alternatives in diabetes treatment has driven research into plant-derived metabolites, particularly essential oils (EOs) with bioactive properties. This study aims to optimize an EO mixture inhibiting two key enzymes involved glucose digestion: pancreatic α-amylase and intestinal α-glucosidase. Methods Essential were extracted from three Moroccan medicinal plants: false yellowhead ( Inula viscosa L.), rose geranium Pelargonium graveolens L'Hér.), lemongrass Cymbopogon citratus (DC.) Stapf.). Gas chromatography-mass spectrometry (GC-MS) analysis identified metabolites each EO. A statistical design was employed evaluate different ratios their inhibitory effects on Additionally, density functional theory (DFT) calculations molecular docking simulations conducted assess the metabolites' electronic properties interaction potential target enzymes. Results GC-MS 32 P . , citronellol (18.67%), eucalyptol (13.30%), 2-octen-1-ol (8.12%) as major components. I contained 18 dominated by 2-camphanol acetate (51.12%) camphol (19.32%), while C. had 23 α-citral (24.70%) 2-isopropenyl-5-methylhex-4-enal (29.25%) constituents. optimal formulation α-glucosidase inhibition a binary of 73% 27% P. In contrast, best blend consisted 56% 44% I. DFT confirmed electrophilic nature supporting enzyme interaction. Molecular suggested that these phytochemicals could exhibit stronger than acarbose, widely used antidiabetic drug. Conclusion These findings highlight optimized formulations managing hyperglycemia developing novel therapies.

Language: Английский

Citations

0
A comparative density functional theory (DFT) and molecular dynamics study on Natamycin and Cefmetazole as effective corrosion inhibitor for mild steel: Electronic properties and adsorption behavior DOI
F. E. Abeng, Abhinay Thakur, Valentine Chikaodili Anadebe

et al.

Computational and Theoretical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 115200 - 115200

Published: March 1, 2025

Language: Английский

Citations

0
Dicationic Ionic Liquids Derivatives for Advanced Corrosion Protection of N80 Carbon Steel: Electrochemical, Computational and Raman Spectroscopic Studies DOI
Abdelkarim Ait Mansour, Mohamed Reda Aouad, Salsabeel Al-Sodies

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142240 - 142240

Published: March 1, 2025

Language: Английский

Citations

0
Advanced synthesis and multifaceted characterization of a 4,4-diaminodiphenylmethane-melamine-formaldehyde terpolymer: anti-corrosion performance and antimicrobial potential in 1 M hydrochloric acid DOI Creative Commons

Rashmi Sehrawat,

Priya Vashishth, Neera Raghav

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(14), P. 11098 - 11114

Published: Jan. 1, 2025

Herein, a 4,4-diaminodiphenylmethane-melamine-formaldehyde (DMF) terpolymer was synthesized and characterized to investigate its anti-corrosion properties for mild steel in 1 M hydrochloric acid electrolyte.

Language: Английский

Citations

0
Cheminformatics-based design and biomedical applications of a new Hydroxyphenylcalix[4] resorcinarene as anti-cancer agent DOI Creative Commons
Solhe F. Alshahateet, Rakan M. Altarawneh, Salah A. Al‐Trawneh

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 13, 2024

Abstract The distinct conformational characteristics, functionality, affordability, low toxicity, and usefulness make calixarene-based compounds a promising treatment option for cancer. aim of the present study is to synthesize new compound assess its anticancer potential on some human cancer cells. synthesized C-4-Hydroxyphenylcalix[4] resorcinarene ( HPCR ) was characterized by several spectroscopic techniques such as 1HNMR, 13CNMR, X-ray crystallographic analysis confirm purity identity. IC 50 values were identified cell lines (U-87, MCF-7, A549) dermal fibroblasts line (HDF) after with standard drug Cisplatin. A significant selective growth inhibitory activity against U-87 A549 obtained at an concentration 100 μM. MOE docking module (version 2015) utilized extent inhibition four cancer-related proteins (3RJ3, 7AXD, 6DUK, 1CGL).

Language: Английский

Citations

1