International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(9), P. 4981 - 4981
Published: May 2, 2024
We
are
living
in
an
era
of
advanced
nanoscience
and
nanotechnology.
Numerous
nanomaterials,
culminating
nanorobots,
have
demonstrated
ingenious
applications
biomedicine,
including
breast
cancer
(BC)
nano-theranostics.
To
solve
the
complicated
problem
BC
heterogeneity,
non-targeted
drug
distribution,
invasive
diagnostics
or
surgery,
resistance
to
classic
onco-therapies
real-time
monitoring
tumors,
nanorobots
designed
perform
multiple
tasks
at
a
small
scale,
even
organelles
molecular
level.
Over
last
few
years,
most
been
bioengineered
as
biomimetic
biocompatible
nano(bio)structures,
resembling
different
organisms
cells,
such
urchin,
spider,
octopus,
fish,
spermatozoon,
flagellar
bacterium
helicoidal
cyanobacterium.
In
this
review,
readers
will
be
able
deepen
their
knowledge
structure,
behavior
role
several
types
among
other
theranostics.
summarized
here
characteristics
many
functionalized
nanodevices
counteract
main
neoplastic
hallmark
features
BC,
from
sustaining
proliferation
evading
anti-growth
signaling
resisting
programmed
cell
death
inducing
angiogenesis,
activating
invasion
metastasis,
preventing
genomic
instability,
avoiding
immune
destruction
deregulating
autophagy.
Most
these
function
targeted
self-propelled
smart
nano-carriers
nano-drug
delivery
systems
(nano-DDSs),
enhancing
efficiency
safety
chemo-,
radio-
photodynamic
therapy,
current
imagistic
techniques
used
diagnosis.
tested
vitro,
using
various
lines,
well
vivo,
mainly
based
on
mice
models.
still
waiting
for
that
low-cost,
wider
transition
favorable
effects
laboratory
clinical
practice.
The European Physical Journal E,
Journal Year:
2025,
Volume and Issue:
48(4-5)
Published: April 7, 2025
This
work
introduces
SwarmRL,
a
Python
package
designed
to
study
intelligent
active
particles.
SwarmRL
provides
an
easy-to-use
interface
for
developing
models
control
microscopic
colloids
using
classical
and
deep
reinforcement
learning
approaches.
These
may
be
deployed
in
simulations
or
real-world
environments
under
common
framework.
We
explain
the
structure
of
software
its
key
features
demonstrate
how
it
can
used
accelerate
research.
With
we
aim
streamline
research
into
micro-robotic
while
bridging
gap
between
experimental
simulation-driven
sciences.
is
available
open-source
on
GitHub
at
https://github.com/SwarmRL/SwarmRL
.
REVIEWS ON ADVANCED MATERIALS SCIENCE,
Journal Year:
2023,
Volume and Issue:
62(1)
Published: Jan. 1, 2023
Abstract
Magnetically
driven
swimming
microrobot
is
a
typical
one
in
the
family
of
microrobots
and
they
can
achieve
navigation
manipulation
low
Reynolds
number
biomedical
environments
with
an
external
magnetic
drive
strategy.
This
study
reviews
recent
advances
material
selection,
structure
design,
fabrication
techniques,
control
method,
applications
for
magnetically
microrobots.
First,
materials
used
were
introduced
effect
selection
on
performance
was
discussed.
Second,
design
manufacturing
techniques
are
reviewed,
followed
by
discussion
main
effective
motion
control,
path
planning,
tracking.
Then,
multi-applications
including
targeted
drug
delivery,
cell
manipulation,
minimally
invasive
surgery
summarized.
Finally,
current
challenges
future
directions
work
Nano Materials Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 1, 2024
Micro/nanoscale
robots
(MNRs)
have
attracted
significant
interest
in
various
fields
because
of
their
flexible
design,
physically
controlled
maneuvering,
and
barrier
targeting.
The
execution
specific
functions
using
MNRs
relies
on
precise
propulsion
methods.
Among
the
diverse
techniques,
physical
is
widely
used
owing
to
its
noninvasive,
safe,
convenient
attributes.
This
review
provides
an
analysis
mechanisms
magnetic,
electric,
thermal,
ultrasound
presents
a
comprehensive
summary
structures,
movements,
applications
while
also
examining
advantages
shortcomings
associated
with
Finally,
challenges
perspectives
future
development
are
presented.
content
this
can
serve
as
multidisciplinary
science
reference
for
physicists,
bioengineers,
clinicians,
roboticists,
chemists
involved
pharmaceutical
design
clinical
therapy
research.
Advanced Materials,
Journal Year:
2023,
Volume and Issue:
36(18)
Published: Dec. 16, 2023
Abstract
Magnetic
microrobots
have
been
developed
for
navigating
microscale
environments
by
means
of
remote
magnetic
fields.
However,
limited
propulsion
speeds
at
small
scales
remain
an
issue
in
the
maneuverability
these
devices
as
force
and
torque
are
proportional
to
their
volume.
Here,
a
microrobotic
superstructure
is
proposed,
which,
analogous
supramolecular
system,
consists
two
or
more
units
that
interconnected
organized
through
physical
(transient)
component
(a
polymeric
frame
thread).
The
superstructures
consist
microfabricated
helical
micromachines
interlocked
gelatin
nanocomposite
containing
iron
oxide
nanoparticles
(IONPs).
While
microhelices
enable
motion
superstructure,
IONPs
serve
heating
transducers
dissolving
chassis
via
hyperthermia.
In
practical
demonstration,
superstructure's
with
gradient
field
large
channel,
disassembly
release
high‐frequency
alternating
field,
corkscrew
locomotion
released
helices
channel
rotating
showcased.
This
adaptable
reacts
different
inputs,
which
can
be
used
perform
complex
delivery
procedures
within
intricate
regions
human
body.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(9), P. 4981 - 4981
Published: May 2, 2024
We
are
living
in
an
era
of
advanced
nanoscience
and
nanotechnology.
Numerous
nanomaterials,
culminating
nanorobots,
have
demonstrated
ingenious
applications
biomedicine,
including
breast
cancer
(BC)
nano-theranostics.
To
solve
the
complicated
problem
BC
heterogeneity,
non-targeted
drug
distribution,
invasive
diagnostics
or
surgery,
resistance
to
classic
onco-therapies
real-time
monitoring
tumors,
nanorobots
designed
perform
multiple
tasks
at
a
small
scale,
even
organelles
molecular
level.
Over
last
few
years,
most
been
bioengineered
as
biomimetic
biocompatible
nano(bio)structures,
resembling
different
organisms
cells,
such
urchin,
spider,
octopus,
fish,
spermatozoon,
flagellar
bacterium
helicoidal
cyanobacterium.
In
this
review,
readers
will
be
able
deepen
their
knowledge
structure,
behavior
role
several
types
among
other
theranostics.
summarized
here
characteristics
many
functionalized
nanodevices
counteract
main
neoplastic
hallmark
features
BC,
from
sustaining
proliferation
evading
anti-growth
signaling
resisting
programmed
cell
death
inducing
angiogenesis,
activating
invasion
metastasis,
preventing
genomic
instability,
avoiding
immune
destruction
deregulating
autophagy.
Most
these
function
targeted
self-propelled
smart
nano-carriers
nano-drug
delivery
systems
(nano-DDSs),
enhancing
efficiency
safety
chemo-,
radio-
photodynamic
therapy,
current
imagistic
techniques
used
diagnosis.
tested
vitro,
using
various
lines,
well
vivo,
mainly
based
on
mice
models.
still
waiting
for
that
low-cost,
wider
transition
favorable
effects
laboratory
clinical
practice.