Layered double hydroxide-based nanomaterials for biomedical applications

Chemical Society Reviews, Journal Year: 2022, Volume and Issue: 51(14), P. 6126 - 6176

Published: Jan. 1, 2022

Against the backdrop of increased public health awareness, inorganic nanomaterials have been widely explored as promising nanoagents for various kinds biomedical applications. Layered double hydroxides (LDHs), with versatile physicochemical advantages including excellent biocompatibility, pH-sensitive biodegradability, highly tunable chemical composition and structure, ease composite formation other materials, shown great promise in In this review, we comprehensively summarize recent advances LDH-based Firstly, material categories are discussed. The preparation surface modification nanomaterials, pristine LDHs, nanocomposites LDH-derived then described. Thereafter, systematically describe potential LDHs applications drug/gene delivery, bioimaging diagnosis, cancer therapy, biosensing, tissue engineering, anti-bacteria. Finally, on basis current state art, conclude insights remaining challenges future prospects rapidly emerging field.

Language: Английский

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Surface Wettability for Skin‐Interfaced Sensors and Devices

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(27)

Published: April 28, 2022

The practical applications of skin-interfaced sensors and devices in daily life hinge on the rational design surface wettability to maintain device integrity achieve improved sensing performance under complex hydrated conditions. Various bio-inspired strategies have been implemented engineer desired for varying Although bodily fluids can negatively affect performance, they also provide a rich reservoir health-relevant information sustained energy next-generation stretchable self-powered devices. As result, manipulation are critical effectively control liquid behavior enhanced performance. with engineered collect analyze health biomarkers while being minimally affected by or ambient humid environments. harvesters benefit from powering on-body electronics. In this review, we first summarize commonly used approaches tune target toward By considering existing challenges, discuss opportunities as small fraction potential future developments, which lead new class use digital personalized medicine.

Language: Английский

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Smartphone-based platforms implementing microfluidic detection with image-based artificial intelligence

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: March 11, 2023

Abstract The frequent outbreak of global infectious diseases has prompted the development rapid and effective diagnostic tools for early screening potential patients in point-of-care testing scenarios. With advances mobile computing power microfluidic technology, smartphone-based health platform drawn significant attention from researchers developing devices that integrate optical detection with artificial intelligence analysis. In this article, we summarize recent progress these platforms, including aspects chips, imaging modalities, supporting components, software algorithms. We document application platforms terms objects, molecules, viruses, cells, parasites. Finally, discuss prospects future platforms.

Language: Английский

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Microfluidic Templated Stem Cell Spheroid Microneedles for Diabetic Wound Treatment

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(28)

Published: April 24, 2023

Wound dressing patches based on stem cells have demonstrated promising potential in the treatment of diabetic wounds, while their capabilities maintenance cell stemness, effective exchange cellular substance, and precise targeting remain to be promoted. Here, a novel spheroid loaded microneedle (MN@SPs) patch is presented using microfluidic templating technology. By leveraging fluid manipulation template, spheroids (SPs) with uniform size can generated situ. The resulting SPs exhibit advanced viability functions, as evidenced by overexpressed genes related extracellular matrix organization angiogenesis. loading these into microneedles (MNs), platform enables delivery multiple active substances, which contribute neovascularization, collagen deposition, tissue reconstruction wounds. Overall, this microfluidic-engineered therapy demonstrates significant promise promoting wound healing.

Language: Английский

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Bioresource Upgrade for Sustainable Energy, Environment, and Biomedicine

Nano-Micro Letters, Journal Year: 2023, Volume and Issue: 15(1)

Published: Jan. 11, 2023

We conceptualize bioresource upgrade for sustainable energy, environment, and biomedicine with a focus on circular economy, sustainability, carbon neutrality using high availability low utilization biomass (HALUB). acme energy-efficient technologies energy material recovery applications. The of thermochemical conversion (TC), biochemical (BC), electrochemical (EC), photochemical (PTC) are summarized HALUB. Microalgal could contribute to biofuel HHV 35.72 MJ Kg

Language: Английский

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Nature-inspired micropatterns

Nature Reviews Methods Primers, Journal Year: 2023, Volume and Issue: 3(1)

Published: Sept. 7, 2023

Language: Английский

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Artificial intelligence-powered microfluidics for nanomedicine and materials synthesis

Nanoscale, Journal Year: 2021, Volume and Issue: 13(46), P. 19352 - 19366

Published: Jan. 1, 2021

Artificial intelligence-powered microfluidics has greatly promoted the development of nanomedicine and material synthesis.

Language: Английский

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Coordination polymer nanozymes-integrated colorimetric microneedle patches for intelligent wound infection management

Chemical Engineering Journal, Journal Year: 2022, Volume and Issue: 444, P. 136640 - 136640

Published: April 29, 2022

Language: Английский

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Transparent Superamphiphobic Material Formed by Hierarchical Nano Re‐Entrant Structure

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(3)

Published: Oct. 15, 2023

Abstract Developing transparent and superamphiphobic materials that can repel low‐surface‐tension liquids is attractive for fundamental research industrial applications. Despite great progress, it remains a daunting challenge to scalably fabricate highly because of the inherent paradox in surface roughness achieve superamphiphobicity optical transparency. Herein, scalable template‐assisted spray coating method developed form hierarchical nano re‐entrant structures eliminate visible‐light scattering while maintaining transmittance above 88% visible region, besides retaining various low surface‐tension liquids. In addition exhibiting improved mechanical, chemical, thermal stabilities, these also be applied on substrates, including curved surfaces solar panels, enhance their stability. This study believes excellent overall properties possess enormous potential applications involving self‐cleaning, anti‐fouling, anti‐counterfeiting.

Language: Английский

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Minimum Minutes Machine-Learning Microfluidic Microbe Monitoring Method (M7)

ACS Nano, Journal Year: 2024, Volume and Issue: 18(6), P. 4862 - 4870

Published: Jan. 17, 2024

Frequent outbreaks of viral diseases have brought substantial negative impacts on society and the economy, they are very difficult to detect, as concentration aerosols in air is low composition complex. The traditional detection method manually collection re-detection, being cumbersome time-consuming. Here we propose a virus aerosol based microfluidic inertial separation spectroscopic analysis technology rapidly accurately detect particles air. chip designed principles laminar flow characteristics, resulting an average efficiency 95.99% for 2 μm particles. We build composite spectrometer platform capture spectral information dynamically. By employing machine-learning techniques, can classify different types entire experiment took less than 30 min compared with hours by PCR detection. Furthermore, our model achieves accuracy 97.87% identifying aerosols, which comparable results obtained from

Language: Английский

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