Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Increased prevalence of cardiovascular-kidney-metabolic syndrome conditions during COVID-19: A propensity score-matched study DOI Creative Commons
Valentina Trimarco, Raffaele Izzo, Daniela Pacella

et al.

Diabetes Research and Clinical Practice, Journal Year: 2024, Volume and Issue: 218, P. 111926 - 111926

Published: Nov. 12, 2024

Language: Английский

Citations

6
A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021) DOI Creative Commons
José Manuel Ramos, José Sánchez‐Payá, Pilar González-de-la-Aleja

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 4, 2025

The study aimed to analyze in-hospital mortality (IHM) among all COVID-19 patients hospitalized in Spain between March 1, 2020, and December 31, 2021, compare two distinct periods: the prevaccination period (March January 2021) vaccination (February 2021). objective was assess impact of on IHM identify associated risk factors, using data from Spain's national hospitalization registry. This retrospective analysis used Spanish National Surveillance System for Hospital Data. primary outcome (IHM). Multivariate logistic regression identified factors across overall period, as well during periods. Risk included age (in 20-year intervals), sex, comorbidities (e.g., hypertension, diabetes, chronic kidney failure, obesity, neurodegenerative disorders, others), admission intensive care unit. A total 524,314 hospitalizations were recorded Spain, with 329,690 194,624 period. Hospitalization rates dropped 697/100,000 people 411/100,000, decreased 16.2 11.5% (adjusted odds ratio [AOR]: 0.71, 95% CI: 0.70-0.73, p < 0.001). rose age, 0.8% aged 18-39 31.7% those ≥80 years (p 0.001), but significant decreases observed groups after vaccination, especially (AOR: 0.76, 0.75-0.79, remained consistent, leukemia, neoplasm, lymphoma posing highest risks, while female sex 0.75, 0.74-0.77, 0.001) dyslipidemia 0.85, 0.32-0.86, protective factors. During 29% lower than adjusting comorbidities. reduced sexes, groups, consistent periods, main factor,

Language: Английский

Citations

0
Association Between Body Mass Index and Glycemic Control in Type 2 Diabetes Mellitus: A Cross-Sectional Study DOI Creative Commons
Deng Li,

Long Jia,

Xiaoli Wu

et al.

Diabetes Metabolic Syndrome and Obesity, Journal Year: 2025, Volume and Issue: Volume 18, P. 555 - 563

Published: Feb. 1, 2025

Body mass index (BMI) is a known risk factor for poor glycemic control in patients with Type 2 diabetes mellitus (T2DM). However, the extent to which BMI correlates glycated hemoglobin (HbA1c) levels and its clinical implications require further investigation. This study aimed assess relationship between HbA1c T2DM explore significance of management optimizing control. A cross-sectional was conducted on 200 from Jinniu District Hospital 2024/04/01 2024/10/03. were recorded, categorized into normal weight (BMI < 25 kg/m²), overweight (25 ≤ 30 obese ≥ kg/m²). Pearson correlation analysis used HbA1c. One-way ANOVA employed compare across categories. significant positive observed (r = 0.45, P 0.001). Obese had significantly higher (8.5 [7.8-9.0]%) compared (7.7 [7.2-8.1]%, 0.01) normal-weight (6.9 [6.4-7.5]%, The graded indicated worsening increasing BMI. Higher associated poorer patients. patients, particular, may benefit more intensive strategies reduce prevent diabetes-related complications. These findings underscore importance integrating reduction plans improve outcomes.

Language: Английский

Citations

0
COVID-19 related complications DOI
Muhamed Adilović

Progress in molecular biology and translational science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Post-covid in patients with obesity: a narrative review DOI

Janeth Vásquez-Granda,

Jessy C. Tarrillo-Olivos,

Naomy R. Pereyra-Urbina

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 3, P. 185 - 185

Published: Feb. 18, 2025

Objective: This study aims to conduct a brief literature review on post-COVID-19 complications in obese patients.Design: A based narrative synthesis.Data Sources: The databases consulted include Science Direct, Scopus, Scielo, Google Scholar, and PubMed.Study Selection: Multiple articles were selected, applying inclusion criteria focused patients, with publications ranging from 2020 2024. Irrelevant studies excluded. final selection included 10 different countries.Data Extraction: From each study, key data extracted, including research design, population characteristics, main reported complications. information was organized narratively facilitate comparison of findings across studies.Results: Out 261,357 articles, 15 relevant selected for the review. These published countries, as follows: Spain (3 middle-income 1 lower-middle income), Italy (1 income, high-income, mixed-income), India (2 middle lower Russia Japan high, middle, low Germany United States Mexico Brazil China high income). indicate that socioeconomic inequalities tend increase risk COVID-19-related mortality.Conclusion: COVID-19 is associated type 2 diabetes, an increased coronary problems, hypertension, nerve damage such polyneuropathy, affecting muscle strength increasing mortality rate respiratory diseases COPD, leading lung fibrosis. Treatment should be comprehensive, vaccines, exercises, physiotherapy, where drug Veklury (remdesivir) has shown efficacy accelerating recovery strengthening immune system. Additionally, post-COVID conditions anxiety, depression, persistent issues addressed.

Language: Английский

Citations

0
Heightened inflammation and immune impairments in those living with obesity may be worsened by coexistence of type 2 diabetes DOI
Philip C. Calder

American Journal of Clinical Nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
The role of plant-based dietary patterns in reducing COVID-19 risk and/or severity in adults: A systematic review and meta-analysis of observational studies DOI Creative Commons
Angeliki Papadaki,

Eimear Mc Coy,

Dimitrios A. Anastasilakis

et al.

Clinical Nutrition, Journal Year: 2024, Volume and Issue: 43(7), P. 1657 - 1666

Published: May 22, 2024

Plant-based dietary patterns (PBDs) might protect against COVID-19 risk and reduce severity of infection. This systematic review with meta-analysis aimed to examine the association between PBDs infection, hospitalization, intensive care unit (ICU) admission, and/or mortality, in adults.

Language: Английский

Citations

2
sMR and PTX3 levels associate with COVID-19 outcome and survival but not with Long COVID DOI Creative Commons
Lisa Hurler, Federica Mescia, Laura Bergamaschi

et al.

iScience, Journal Year: 2024, Volume and Issue: 27(7), P. 110162 - 110162

Published: June 1, 2024

Biomarkers for monitoring COVID-19 disease course are lacking. Study aim was to identify biomarkers associated with severity, survival, long-term outcome, and Long COVID. As excessive macrophages activation is a hallmark of complement key in this, we selected the following proteins involved these processes: PTX3, C1q, C1-INH, C1s/C1-INH, sMR. EDTA-plasma concentrations were measured 215 patients 47 controls using ELISA. sMR, C1s/C1-INH levels severity. PTX3 sMR also survival immune recovery. Lastly, associate ICU admittance. (AUC 0.85) 0.78) good markers especially when used combination 0.88). No association between biomarker COVID observed. has not previously been admittance or may serve as marker course.

Language: Английский

Citations

2
Posttraumatic stress symptoms among Chinese university students during the COVID-19 pandemic: Prevalence, correlates, and mental health help-seeking DOI

Rui-Yao Wu,

Lin-Feng Ge,

Bao‐Liang Zhong

et al.

World Journal of Psychiatry, Journal Year: 2024, Volume and Issue: 15(1)

Published: Dec. 18, 2024

Revisiting the epidemiology of posttraumatic stress symptoms (PTSSs) among university students during coronavirus disease 2019 (COVID-19) pandemic as well understanding mental health help-seeking behavior individuals with PTSSs has critical implications for public strategies in future medical pandemics. To investigate prevalence and correlates first wave COVID-19 China to examine behaviors these students. A total 2507 Chinese were recruited via snowball sampling. The completed Seven-item Screening Scale Post-traumatic Stress Disorder China. Sociodemographic characteristics, pandemic-related also collected. participants was 28.0%. Seven significant identified (odds ratio = 1.23-3.65, P ≤ 0.024): Female sex, being 19 years old or older, living others alone, a low level family economic status, fair poor interpersonal relationships, severe very local pandemic, having members diagnosed COVID-19. However, only 3.28% reported seeking help from specialists. Among 23 who sought specialists, 13 opted online telephone-based psychological consultation. Our data suggest that there high risk unmet needs pandemic. delivery services telephone is promising approach address needs.

Language: Английский

Citations

0
Association between demographic, clinical characteristics and severe complications by SARS-CoV-2 infection in a community-based healthcare network in Chile DOI Creative Commons
Javiera Léniz, Sam Hernández-Jaña, Mauricio Soto

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(12), P. e0314376 - e0314376

Published: Dec. 30, 2024

Background Most of the evidence on risk factors for COVID-19 complications comes from North America or Europe with very little research Latin-America. We aimed to evaluate association between sociodemographic, clinical and among adults in Chile, fifth Latin-American country more reported cases since de beginning Pandemic. Methods A retrospective population-based cohort study using data electronic health records a large Primary Care Network, linked national hospital, immunization, Covid-19 PCR surveillance, mortality birth records. included people 18+ years old enrolled Network 1 st January 2020 31 December 2021. Using Multivariate Cox proportional hazard models, we characteristics three complications: (1) hospital admission, (2) an ICU (3) death due infection that occurred Results 44,674 were included. The mean age was 44.30 (sd 17.31), 55.6% female, 15.9% had type healthcare insurance lowest category income, 11.6% 9.4% record hypertension diabetes mellitus diagnosis. Among people, 455 (1.02%) admission 216(0.48%) them also admission. people,148(0.33%) died infection. Older male sex consistently associated higher complications. Hypertension death, but not admissions Having two vaccine doses compared no lower any (HR 0.81; 95% CI 0.77–0.84), 0.60; 0.57–0.63) 0.50; 0.46–0.54). Pregnant puerperal women likely be admitted 2.89; 1.41–5.89) 3.04; 1.01–9.14). Conclusions Sociodemographic such as age, pre-existing conditions comparable those similar studies higher-income countries, can used predict severity patients.

Language: Английский

Citations

0