Eu(III)-Functionalized MOF-Based Dual-Emission Ratiometric Sensor Integrated with Logic Gate Operation for Efficient Detection of Hippuric Acid in Urine and Serum

Inorganic Chemistry, Journal Year: 2023, Volume and Issue: 62(6), P. 2715 - 2725

Published: Jan. 27, 2023

With the introduction of Eu3+ ions as secondary fluorescent signal reporter and sensing active sites, a dual-emission ratiometric sensor Eu3+@NiMOF (Eu3+ functional NiMOF) for hippuric acid (HA) detection in urine serum was fabricated via postsynthetic encapsulating strategy. Based on two emission signals at 441 nm (turn-on) 628 (turn-off), produced provided enhanced sensitivity, higher selectivity, 9.7 times lower limits (LOD) HA (2.38 μM, 0.42 μg·mL-1) than that pristine NiMOF. Considering high sensitivity visualization results, further exploration intelligent applications process carried out by constructing tandem combinational logic gate to improve practicability convenience with help smartphone. This work provides promising approach developing MOF-based sensors detect biomarkers.

Language: Английский

---

A bifunctional luminescence sensor for biomarkers detection in serum and urine based on chemorobust Nickel(II) metal-organic framework

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2023, Volume and Issue: 306, P. 123585 - 123585

Published: Oct. 28, 2023

Language: Английский

---

Two Chemorobust Cobalt(II) Organic Frameworks as High Sensitivity and Selectivity Sensors for Efficient Detection of 3-Nitrotyrosine Biomarker in Serum

Crystal Growth & Design, Journal Year: 2023, Volume and Issue: 23(11), P. 7716 - 7724

Published: Oct. 4, 2023

Rapid detection of the 3-nitrotyrosine (3-NT) biomarker in serum is great significance clinical diagnosis and daily disease monitoring. In this work, two chemorobust 3D metal–organic frameworks (MOFs) [Co(DBrTPA)(NMP)]n (CoMOF-1) [Co5(DBrTPA)4(DMF)6(HCOO)2]n (CoMOF-2) were fabricated from a halogen-modified ligand 2,5-dibromoterephthalic (H2DBrTPA) cobalt(II) clusters under solvothermal conditions. The introduction halogens can improve stability overall framework different media pH environments, which also endow CoMOFs with potential as luminescent sensors high sensitivity selectivity, fast response, good anti-interference, well recyclable performance detecting 3-NT PBS buffer solution through quenching effects, Ksv values being 9.19 × 104 M–1 for CoMOF-1 1.05 105 CoMOF-2 LODs low 23.6 ng·mL–1 20.1 CoMOF-2. Furthermore, developed employed to quantify real samples, satisfactory results. addition, possible sensing mechanisms toward discussed photoinduced electron transfer spectral overlaps. This work demonstrated excellent MOF-based provided an outlook design help artificial intelligence machine learning.

Language: Английский

---

Tb(III) functionalized MOF based self-calibrating sensor integrated with logic gate operation for efficient epinephrine detection in serum

Journal of Rare Earths, Journal Year: 2023, Volume and Issue: 42(5), P. 987 - 994

Published: April 19, 2023

Language: Английский

---

Multifunctional Fe-doped carbon dots and metal-organic frameworks nanoreactor for cascade degradation and detection of organophosphorus pesticides

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 464, P. 142480 - 142480

Published: March 17, 2023

Language: Английский

---

Chemorobust dye-encapsulated framework as dual-emission self-calibrating ratiometric sensor for intelligent detection of toluene exposure biomarker in urine

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2023, Volume and Issue: 296, P. 122637 - 122637

Published: March 17, 2023

Language: Английский

---

Heterometallic ZnHoMOF as a Dual-Responsive Luminescence Sensor for Efficient Detection of Hippuric Acid Biomarker and Nitrofuran Antibiotics

Molecules, Journal Year: 2023, Volume and Issue: 28(17), P. 6274 - 6274

Published: Aug. 27, 2023

Developing efficient and sensitive MOF-based luminescence sensors for bioactive molecule detection is of great significance remains a challenge. Benefiting from favorable chemical thermal stability, as well excellent performance, porous Zn(II)Ho(III) heterometallic-organic framework (ZnHoMOF) was selected here bifunctional sensor the early diagnosis toluene exposure biomarker hippuric acid (HA) through "turn-on" enhancing response daily monitoring NFT/NFZ antibiotics "turn-off" quenching effects in aqueous media with high sensitivity, acceptable selectivity, good anti-interference, exceptional recyclability low limits (LODs) 0.7 ppm HA, 0.04 NFT, 0.05 NFZ. Moreover, developed employed to quantify HA diluted urine samples natural river water satisfactory results. In addition, sensing mechanisms ZnHoMOF dual-response chemosensor were conducted view photo-induced electron transfer (PET), inner filter (IFEs), help time-dependent density functional theory (TD-DFT) spectral overlap experiments.

Language: Английский

---

A dual‐responsive luminescent sensor for efficient detection of 3‐nitrotyrosine and dipicolinic acid biomarkers based on copper(II) organic framework

Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: 38(6)

Published: March 26, 2024

The trace detection of biomarkers in real samples has profound a most important significance the early diagnosis and daily monitoring diseases. Based on ligand pre‐design strategy, novel 3D CuMOF, with formula {[Cu 4 (BTPB)( μ 2 ‐OH) (H O) 5 ]·3H O} n , was fabricated by using hexacarboxyl 1,4‐bis(2,4,6‐tricarboxylpyrid‐5‐yl)benzene 6 BTPB) tetranuclear {Cu (COO) ( } SBUs. Benefiting from robust framework unique luminescence performance, prepared CuMOF displays great potential as dual‐responsive efficient luminescent sensor “turn‐off” 3‐nitrotyrosine (3‐NT) biomarker “turn‐on” detecting anthrax dipicolinic acid (DPA), limits (LOD) for 3‐NT DPA being 110.8 ng/ml 85.2 ng/ml, respectively. Additionally, practicality compatibility such developed sensors were verified quantifying diluted serum urine satisfactory recoveries. Further, theoretical calculations energy levels well spectral overlap between analytes conducted to elucidate possible sensing mechanisms. This work demonstrated that MOFs‐based are evolving an efficacious equable approach samples.

Language: Английский

---

Ni(II)-MOF based hypersensitive dual-function luminescent sensor towards 3-nitrotyrosine biomarker and 6-Propyl-2-thiouracil antithyroid drug in Urine

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Luminescent NiMOF demonstrated remarkable capabilities in efficient, sensitive and intelligent detection of 3-NT biomarker 6-PTU thyroid drug urine through luminescence quenching effects.

Language: Английский

---

A dual-purpose electrode material for voltametric quantification of uric acid and supercapacitor performance using dysprosium-doped CaZrO3

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113081 - 113081

Published: Feb. 1, 2025

Language: Английский

---