The nucleic acid detection using CRISPR/Cas biosensing system with micro-nano modality for point-of-care applications DOI
Liang Zhao, Zihao Zhao, Ning Li

et al.

Talanta, Journal Year: 2024, Volume and Issue: 286, P. 127457 - 127457

Published: Dec. 24, 2024

Language: Английский

CRISPR integrated biosensors: A new paradigm for cancer detection DOI

Ashok Saini,

Neeraj Dilbaghi, Neelam Yadav

et al.

Clinica Chimica Acta, Journal Year: 2025, Volume and Issue: 569, P. 120179 - 120179

Published: Feb. 1, 2025

Language: Английский

Citations

1
Detection of Tetracycline with a CRISPR/Cas12a Aptasensor Using a Highly Efficient Fluorescent Polystyrene Microsphere Reporter System DOI

Bong Jing Yee,

Siti Nurul Azian Zakaria, Rona Chandrawati

et al.

ACS Synthetic Biology, Journal Year: 2024, Volume and Issue: 13(7), P. 2166 - 2176

Published: June 12, 2024

CRISPR-based diagnostics use the CRISPR-Cas system

Language: Английский

Citations

6
CRISPR revolution: Unleashing precision pathogen detection to safeguard public health and food safety DOI
Jacob Tizhe Liberty, Sabri Bromage,

Endurance Peter

et al.

Methods, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
CRISPR/Cas-Based Nanobiosensor Using Plasmonic Nanomaterials to Detect Disease Biomarkers DOI Creative Commons
Jin‐Ha Choi, Jinho Yoon,

Meizi Chen

et al.

BioChip Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Language: Английский

Citations

0
Nanomaterials-Integrated CRISPR/Cas Systems: Expanding the Toolbox for Optical Detection DOI
Tianying Sun, Weiwei He, Xiangmei Chen

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Nanomaterials-integrated CRISPR/Cas systems have rapidly emerged as powerful next-generation platforms for optical biosensing. These integrated harness the precision of CRISPR/Cas-mediated nucleic acid detection while leveraging unique properties nanomaterials to achieve enhanced sensitivity and expanded analytical capabilities, thereby broadening their diagnostic potential. By incorporating a diverse range nanomaterials, these effectively expand toolbox detection, offering adaptable solutions tailored various challenges. This review provides comprehensive overview successfully into CRISPR/Cas-based sensing systems. It examines multiple modalities, including fluorescence, electrochemiluminescence, colorimetry, surface-enhanced Raman spectroscopy, highlighting how facilitate signal amplification, enable multiplexing, support development point-of-care applications. Additionally, practical applications in critical fields such healthcare diagnostics environmental monitoring are showcased. While offer considerable advantages, several real-world challenges complexity assay workflows, impact cost, regulatory hurdles must be addressed before widespread implementation can achieved. identifying obstacles proposing strategic solutions, we aim pave way continued advancement adoption nanomaterial-integrated biosensing technologies.

Language: Английский

Citations

0
The nucleic acid detection using CRISPR/Cas biosensing system with micro-nano modality for point-of-care applications DOI
Liang Zhao, Zihao Zhao, Ning Li

et al.

Talanta, Journal Year: 2024, Volume and Issue: 286, P. 127457 - 127457

Published: Dec. 24, 2024

Language: Английский

Citations

0