Construction and electrochemical performances of AuNPs functionalized bimetallic ZnCo-MOF derivatives and reduced graphene hybrid structure for highly sensitive prostate specific antigen detection DOI
Ying Yang,

Q. Cai,

Wenda Wang

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112589 - 112589

Published: Dec. 1, 2024

Language: Английский

Wet chemical synthesis of hematite: Its magnetic property and sensing activity DOI

Saikat Jati,

Bodhishatwa Roy,

Sanatan Chattopadhyay

et al.

Materials Science and Engineering B, Journal Year: 2025, Volume and Issue: 314, P. 118057 - 118057

Published: Feb. 6, 2025

Language: Английский

Citations

1

Label-free electrochemical biosensor with magnetic self-assembly constructed via PNA-DNA hybridization process on α-Fe2O3/Fe3O4 nanosheets for APOE ε4 genes ultrasensitive detection DOI
Zhihao Xu, Zhixiang Lv,

Haitao Yang

et al.

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 161, P. 108847 - 108847

Published: Nov. 15, 2024

Language: Английский

Citations

4

Trends in Aptasensing and the Enhancement of Diagnostic Efficiency and Accuracy DOI
Mohammad A. Ansari, Damini Verma,

Mohd-Akmal Hamizan

et al.

ACS Synthetic Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 21 - 40

Published: Jan. 6, 2025

The field of healthcare diagnostics is navigating complex challenges driven by evolving patient demographics and the rapid advancement new technologies worldwide. In response to these challenges, biosensors offer distinctive advantages over traditional diagnostic methods, such as cost-effectiveness, enhanced specificity, adaptability, making their integration with point-of-care (POC) platforms more feasible. recent years, aptasensors have significantly evolved in capabilities through emerging microfluidics, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems, wearable devices, machine learning (ML), driving progress precision medicine global solutions. Moreover, advancements not only improve accuracy but also hold potential revolutionize early detection, reduce costs, outcomes, especially resource-limited settings. This Account examines key advancements, focusing on how scientific breakthroughs, including artificial intelligence (AI), improved sensitivity precision. Additionally, has enabled real-time monitoring data analysis, fostering advances personalized healthcare. Furthermore, commercialization aptasensor could increase availability clinical settings support use widespread solutions for health challenges. Hence, this review discusses technological improvements, practical uses, prospects while surrounding standardization, validation, interdisciplinary collaboration application. Finally, ongoing efforts address are ensure that can be effectively implemented diverse systems.

Language: Английский

Citations

0

Functionalized borophene with methylene blue tagging for sensitive electrochemical detection of PFOA DOI

Sana Jawaid,

Sadam Hussain Tumrani,

Razium Ali Soomro

et al.

Materials Science and Engineering B, Journal Year: 2025, Volume and Issue: 314, P. 118073 - 118073

Published: Feb. 3, 2025

Language: Английский

Citations

0

A Dual Nano-Signal Probe-Based Electrochemical Immunosensor for the Simultaneous Detection of Two Biomarkers in Gastric Cancer DOI Creative Commons

Li-Ting Su,

Zhenqing Yang, Hua‐Ping Peng

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 80 - 80

Published: Jan. 31, 2025

Detecting multiple tumor markers is of great importance. It helps in early cancer detection, accurate diagnosis, and monitoring treatment. In this work, gold nanoparticles–toluidine blue–graphene oxide (AuNPs-TB–GO) nanoparticles–carboxyl ferrocene–tungsten disulfide (AuNPs–FMC–WS2) nanocomposites were prepared for labeling Carcinoembryonic antigen (CEA) antibody Carbohydrate 72–4 (CA72-4) antibody, respectively, used as two kinds probes with different electrochemical signals. With the excellent magnetic performance biotin immune beads (IMBs), biofunctional IMBs firmly deposited on glassy carbon electrode (MGCE) surface by applying a constant field, then CEA CA72-4 immobilized avidin–biotin conjugation. The assay was based change detection peak current. Under optimum experimental conditions, linear range two-component immunosensor from 0.01 to 120 ng/mL, low limit 0.003 0.05 35 U/mL, 0.016 U/mL. results showed that proposed enabled simultaneous exhibited good reproducibility, high selectivity, sensitivity. particular, multiplexed immunoassay approach does not require sophisticated fabrication well-suited high-throughput biosensing application other areas.

Language: Английский

Citations

0

A label-free electrochemical immunosensor utilizing Au-functionalized MOF-derived Co3O4/CNTs polyhedral nanocomposites for ultrasensitive detection of prostate-specific antigen DOI
Wenda Wang,

Q. Cai,

Yuxiu Li

et al.

Surfaces and Interfaces, Journal Year: 2025, Volume and Issue: unknown, P. 106047 - 106047

Published: Feb. 1, 2025

Language: Английский

Citations

0

A Hydrothermal and Combustion-Reduction Process with Polyvinyl Pyrrolidone as a Restricted Growth Agent and Galactose as a Reducing Agent for the Fabrication of Rod-like α-Fe2O3/Fe3O4 Magnetic Nanocomposites DOI Open Access
Yuxuan Bai, Zhou Wang, Yongjin Li

et al.

Materials, Journal Year: 2025, Volume and Issue: 18(5), P. 1014 - 1014

Published: Feb. 25, 2025

A hydrothermal and combustion-reduction process with polyvinyl pyrrolidone (PVP) as a restricted growth agent galactose reducing was developed for the fabrication of rod-like α-Fe2O3/Fe3O4 magnetic nanocomposites (MNCs). Firstly, β-FeOOH nanorods (NRs) were fabricated by method, PVP agent. To obtain smaller size better applications in biomedical field, concentrations FeCl3 PVP, temperature, time optimized 0.171 M, 0.163 mM, 100 °C, 8 h, NRs 193.1 nm average length 43.2 diameter. Then, precursors, MNCs prepared via agent; factors calcination temperature mass ratio assessed 300 0.5 1:2, respectively. The under conditions 81.6 23.9 diameter, while their saturation magnetization reached 69.8 emu/g.

Language: Английский

Citations

0

Precise Detection of ProGRP Using Label-Free Electrochemical Biosensor based on α-Fe2O3/Fe3O4 heterogeneous nanorods DOI
Zhihao Xu, Hezhong Ouyang,

Haoda Zhang

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

3

Synergistic enhancement mediated sensitive SERS-based immunoassay of PSA using versatile PDMS@AgNPs@ZIF-67 biomimetic substrates DOI

Hengwei Zhao,

Zhihan Liu, Shijiao Fu

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 239, P. 113963 - 113963

Published: May 13, 2024

Language: Английский

Citations

2

Construction and electrochemical performances of AuNPs functionalized bimetallic ZnCo-MOF derivatives and reduced graphene hybrid structure for highly sensitive prostate specific antigen detection DOI
Ying Yang,

Q. Cai,

Wenda Wang

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112589 - 112589

Published: Dec. 1, 2024

Language: Английский

Citations

0