Surface plasmon resonance detection of anti-cancer drug flutamide by graphitic carbon nitride/chitosan nanocomposite

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 17, 2025

The g-C3N4/CS biosensor was designed, fabricated, and tested using compounds such as glucose, urine, lactose, flutamide at a molarity of 10 µM, which could demonstrate high sensitivity 200 μm-1 for flutamide. Powerful effective medium theory FDTD simulation were used to predict the most favorable mode plasmonic properties graphite carbon nitride chitosan nanocomposite. research also explores characteristics surface plasmon resonance exhibited by nanocomposite content is adjusted. Subsequent simulations are conducted on nanocomposites incorporating thin layer modified gold structure. intricate ultimately reveal optimal combination, under three different pH conditions (6.2, 7.2, 8). In acidic conditions, kinetic profile yielded KD= 3.45 × 10−7, surpassing KD value film. Au significantly outperformed alternative material. demonstrated linear behavior across wide concentration range from 1 150 achieving detection limit 120 nM with its sensitivity.

Language: Английский

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Self-ratiometric fluorescence approach based on room-temperature instantaneously synthesized carbon dots from Folin's reagent and ethanolamine for determination of nitroxinil in water, milk, and food samples

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1323, P. 343061 - 343061

Published: Aug. 5, 2024

Language: Английский

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Sustainable quantification of glycopyrronium, indacaterol, and mometasone along with two genotoxic impurities in a recently approved fixed-dose breezhaler formulations and biological fluids: A machine learning-augmented UV-spectroscopic approach

Microchemical Journal, Journal Year: 2024, Volume and Issue: 206, P. 111586 - 111586

Published: Sept. 6, 2024

Language: Английский

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Unlocking multifaceted applications of fava bean empty pods-derived CQDs for smart multi-target nanoprobing of pH, temperature, and p-nitrophenol

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 112869 - 112869

Published: Jan. 1, 2025

Language: Английский

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Exploring Green Practices: a Review of Carbon Dot-Based Sustainable Sensing Approaches

Journal of Fluorescence, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Language: Английский

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Nitrogen and Sulfur Co‐Doped Carbon Quantum Dots as Fluorescent Nanosensors for Determination of Two Tetracycline Antibiotics in Dosage Forms and Human Plasma: Compliance With Greenness Metrics

Luminescence, Journal Year: 2024, Volume and Issue: 39(10)

Published: Oct. 1, 2024

ABSTRACT In this study, a novel, sensitive, and cost‐effective spectrofluorimetric approach was established for the estimation of two important tetracycline antibiotics, doxycycline, without any pre‐treatment procedures or harsh reaction conditions, first time. The proposed methodology is based on quantitative quenching effect each doxycycline native fluorescence nitrogen sulfur co‐doped carbon quantum dots (NS‐CQDs). A simple ultrafast applied to synthesize NS‐CQDs using thiosemicarbazide citric acid as starting materials after incubation in microwave only 1 min. Utilizing an excitation wavelength 360 nm, showed maximum emission peak at 430 nm. Calibration curves revealed excellent linearity within ranges 1.0–10.0 0.8–12.0 μg/mL with detection limits 0.20 0.09 respectively. Due method's high sensitivity selectivity, determination studied drugs their capsules human plasma samples %recoveries. developed validated according ICHQ2(R2) guidelines. GAPI AGREE metric tools were used verify greenness eco‐friendliness, suggesting its use green substitute analysis drugs.

Language: Английский

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Design and synthesis of high quantum yield doped carbon nano probe derived from household sources for sensing of the anti-GERD drug pantoprazole

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 325, P. 125067 - 125067

Published: Aug. 30, 2024

Language: Английский

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Nano-scale multi-spectroscopic analysis of the anti-fibromyalgia drug pregabalin based on dihydropyridine ring formation with sustainability and whiteness evaluation

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 325, P. 125151 - 125151

Published: Sept. 17, 2024

Language: Английский

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Integrating bio-based luminescent CQDs nanosensors and factorial-design-optimized sugaring-out homogenous liquid–liquid microextraction for sensitive determination of two neurologic drugs

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113034 - 113034

Published: Feb. 1, 2025

Language: Английский

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Influence of anti-androgen cyproterone acetate on sperm characteristics, testosterone level, testicular and liver histology in male goldfish (Carassius auratus)

Emerging contaminants, Journal Year: 2025, Volume and Issue: unknown, P. 100507 - 100507

Published: April 1, 2025

Language: Английский

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