Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism DOI Open Access
Heidi M. Blank, Ophelia Papoulas, Nairita Maitra

et al.

Molecular Biology of the Cell, Journal Year: 2020, Volume and Issue: 31(10), P. 1069 - 1084

Published: May 1, 2020

In several systems, including budding yeast, cell cycle-dependent changes in the transcriptome are well studied. contrast, few studies queried proteome during division. There is also little information about dynamic metabolites and lipids cycle. Here, authors present such for dividing yeast cells.

Language: Английский

Unraveling Interfaces between Energy Metabolism and Cell Cycle in Plants DOI

João Antonio Siqueira,

Pablo R. Hardoim,

Paulo C.G. Ferreira

et al.

Trends in Plant Science, Journal Year: 2018, Volume and Issue: 23(8), P. 731 - 747

Published: June 19, 2018

Language: Английский

Citations

58
Untargeted metabolomics links glutathione to bacterial cell cycle progression DOI
Johannes Hartl, Patrick Kiefer, Andreas Kaczmarczyk

et al.

Nature Metabolism, Journal Year: 2020, Volume and Issue: 2(2), P. 153 - 166

Published: Feb. 3, 2020

Language: Английский

Citations

50
Integration of Multiple Metabolic Signals Determines Cell Fate Prior to Commitment DOI Creative Commons
Orlando Argüello‐Miranda, Yanjie Liu, N. Ezgi Wood

et al.

Molecular Cell, Journal Year: 2018, Volume and Issue: 71(5), P. 733 - 744.e11

Published: Aug. 30, 2018

Language: Английский

Citations

47
Building blocks are synthesized on demand during the yeast cell cycle DOI Open Access
Kate Campbell, Jakub Orzechowski Westholm, Sergo Kasvandik

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2020, Volume and Issue: 117(14), P. 7575 - 7583

Published: March 25, 2020

For cells to replicate, a sufficient supply of biosynthetic precursors is needed, necessitating the concerted action metabolism and protein synthesis during progressive phases cell division. A global understanding which processes are involved how they temporally regulated replication is, however, currently lacking. Here, quantitative multiomics analysis used generate holistic view eukaryal cycle, using budding yeast Saccharomyces cerevisiae Protein central carbon pathways such as glycolysis amino acid shown synchronize their respective abundance profiles with division, pathway-specific changes in metabolite also being reflected by relative increase mitochondrial volume, fluorescence microscopy. These results show precursor production be meet phase-specific demands

Language: Английский

Citations

41
Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism DOI Open Access
Heidi M. Blank, Ophelia Papoulas, Nairita Maitra

et al.

Molecular Biology of the Cell, Journal Year: 2020, Volume and Issue: 31(10), P. 1069 - 1084

Published: May 1, 2020

In several systems, including budding yeast, cell cycle-dependent changes in the transcriptome are well studied. contrast, few studies queried proteome during division. There is also little information about dynamic metabolites and lipids cycle. Here, authors present such for dividing yeast cells.

Language: Английский

Citations

40