BMC Genomics,
Journal Year:
2020,
Volume and Issue:
21(1)
Published: Jan. 8, 2020
Anthocyanins
are
common
substances
with
many
agro-food
industrial
applications.
However,
anthocyanins
generally
considered
to
be
found
only
in
natural
plants.
Our
previous
study
isolated
and
purified
the
fungus
Aspergillus
sydowii
H-1,
which
can
produce
purple
pigments
during
fermentation.
To
understand
characteristics
of
this
strain,
a
transcriptomic
metabolomic
comparative
analysis
was
performed
A.
H-1
from
second
eighth
days
fermentation,
confer
different
pigment
production.We
five
remarkably
production
on
day
fermentation
compared
LC-MS/MS
combined
other
suggested
that
contained
anthocyanins.
A
total
28
transcripts
related
anthocyanin
biosynthesis
pathway
identified
almost
all
genes
displayed
high
correlations
metabolome.
Among
them,
chalcone
synthase
gene
(CHS)
cinnamate-4-hydroxylase
(C4H)
were
using
de
novo
assembly
method.
Interestingly,
best
hits
these
two
belonged
plant
species.
Finally,
we
also
530
lncRNAs
our
datasets,
among
three
targeted
via
cis-regulation,
provided
clues
for
understanding
underlying
mechanism
fungi.We
first
reported
produced
fungus,
H-1.
Totally,
31
candidate
involved
biosynthesis,
CHS
C4H,
known
as
key
strain
H1,
indicated
may
contribute
producing
This
discovery
expanded
knowledges
direction
anthocyanin.
Molecules,
Journal Year:
2019,
Volume and Issue:
24(4), P. 796 - 796
Published: Feb. 22, 2019
Tropane
alkaloids
(TA)
are
valuable
secondary
plant
metabolites
which
mostly
found
in
high
concentrations
the
Solanaceae
and
Erythroxylaceae
families.
The
TAs,
characterized
by
their
unique
bicyclic
tropane
ring
system,
can
be
divided
into
three
major
groups:
hyoscyamine
scopolamine,
cocaine
calystegines.
Although
all
TAs
have
same
basic
structure,
they
differ
immensely
biological,
chemical
pharmacological
properties.
Scopolamine,
also
known
as
hyoscine,
has
largest
legitimate
market
a
agent
due
to
its
treatment
of
nausea,
vomiting,
motion
sickness,
well
smooth
muscle
spasms
while
is
2nd
most
frequently
consumed
illicit
drug
globally.
This
review
provides
comprehensive
overview
highlighting
structural
diversity,
use
pharmaceutical
therapy
from
both
historical
modern
perspectives,
natural
biosynthesis
Natural Product Reports,
Journal Year:
2020,
Volume and Issue:
38(1), P. 103 - 129
Published: Aug. 3, 2020
Alkaloids
from
plants
are
characterised
by
structural
diversity
and
bioactivity,
maintain
a
privileged
position
in
both
modern
traditional
medicines.
In
recent
years,
there
have
been
significant
advances
elucidating
the
biosynthetic
origins
of
plant
alkaloids.
this
review,
I
will
describe
progress
made
determining
metabolic
so-called
true
alkaloids,
specialised
metabolites
derived
amino
acids
containing
nitrogen
heterocycle.
By
identifying
key
steps
that
feature
majority
pathways,
highlight
roles
played
modifications
to
primary
metabolism,
iminium
reactivity
spontaneous
reactions
molecular
evolutionary
these
pathways.
BMC Plant Biology,
Journal Year:
2022,
Volume and Issue:
22(1)
Published: Jan. 11, 2022
Fruits
are
vital
food
resources
as
they
loaded
with
bioactive
compounds
varying
different
stages
of
ripening.
As
the
fruit
ripens,
a
dynamic
color
change
is
observed
from
green
to
yellow
red
due
biosynthesis
pigments
like
chlorophyll,
carotenoids,
and
anthocyanins.
Apart
making
attractive
being
visual
indicator
ripening
status,
add
value
ripened
by
them
source
nutraceuticals
industrial
products.
matures,
it
undergoes
biochemical
changes
which
alter
pigment
composition
fruits.The
synthesis,
degradation
retention
pathways
mediated
hormonal,
genetic,
environmental
factors.
Manipulation
underlying
regulatory
mechanisms
during
suggests
ways
enhance
desired
in
fruits
biotechnological
interventions.
Here
we
report,
in-depth
insight
into
dynamics
action.This
review
emphasizes
role
an
asset
augment
nutritive
value,
antioxidant
levels
net
carbon
gain
fruits;
for
biofortification
have
tremendous
along
tool
predict
harvest.
This
report
will
be
great
utility
harvesters,
traders,
consumers,
natural
product
divisions
extract
leading
nutraceutical
potential
preferred
biosynthesized
at
stages.
Metabolites,
Journal Year:
2022,
Volume and Issue:
12(9), P. 871 - 871
Published: Sept. 16, 2022
Anthocyanins,
carotenoids,
and
betalains
are
known
as
the
three
major
pigments
in
plant
kingdom.
Anthocyanins
flavonoids
derived
from
phenylpropanoid
pathway.
They
undergo
acylation
glycosylation
cytoplasm
to
produce
anthocyanin
derivatives
deposits
cytoplasm.
Anthocyanin
biosynthesis
is
regulated
by
MBW
(comprised
R2R3-MYB,
basic
helix-loop-helix
(bHLH)
WD40)
complex.
Carotenoids
fat-soluble
terpenoids
whose
synthetic
genes
also
As
precursors
for
synthesis
of
hormones
nutrients,
carotenoids
not
only
synthesized
plants,
but
some
fungi
bacteria,
play
an
important
role
photosynthesis.
Betalains
special
water-soluble
that
exist
Caryophyllaceae
plants.
Compared
anthocyanins
regulation
mechanism
simpler,
starting
tyrosine,
MYB
(myeloblastosis).
Recently,
a
considerable
amount
novel
information
has
been
gathered
on
pigment
biosynthesis,
specifically
with
respect
aspects.
In
this
review,
we
summarize
knowledge
current
gaps
our
understanding
view
highlighting
opportunities
development
pigment-rich
New Phytologist,
Journal Year:
2019,
Volume and Issue:
224(1), P. 71 - 85
Published: June 7, 2019
Within
the
angiosperm
order
Caryophyllales,
an
unusual
class
of
pigments
known
as
betalains
can
replace
otherwise
ubiquitous
anthocyanins.
In
contrast
to
phenylalanine-derived
anthocyanins,
are
tyrosine-derived
which
contain
chromophore
betalamic
acid.
The
origin
betalain
within
Caryophyllales
and
their
mutual
exclusion
with
anthocyanin
have
been
subject
considerable
research.
recent
years,
numerous
discoveries,
accelerated
by
-omic
scale
data,
phylogenetics
synthetic
biology,
shed
light
on
evolution
biosynthetic
pathway
in
Caryophyllales.
These
advances
include
elucidation
steps
pathway,
identification
transcriptional
regulators
synthesis,
resolution
phylogenetic
history
key
genes,
insight
into
a
role
for
modulation
primary
metabolism
synthesis.
Here
we
review
how
molecular
genetics
advanced
our
understanding
discuss
impact
revealing
its
evolutionary
history.
these
insights,
explore
new
betalains,
homoplastic
distribution
pigmentation
We
conclude
speculative
conceptual
model
stepwise
emergence
pigmentation.
Molecules,
Journal Year:
2019,
Volume and Issue:
24(6), P. 1114 - 1114
Published: March 20, 2019
Pitaya
(Hylocereus
polyrhizus)
has
attracted
much
interest
from
consumers
as
it
is
a
novelty
fruit
with
high
nutrient
content
and
tolerance
to
drought
stress.
As
group
of
attractive
pigment-
health-promoting
natural
compounds,
betalains
represent
visual
feature
for
pitaya
quality.
However,
little
information
on
the
correlation
between
relevant
metabolites
exists
so
far.
Currently,
color
(Commission
International
del'Eclairage,
CIE)
parameters,
betalain
contents,
untargeted
metabolic
profiling
(gas
chromatography-time-of-flight-mass
spectrometry,
GC⁻MS
liquid
chromatography
tandem
mass
LC⁻MS)
have
been
examined
'Zihonglong'
fruits
at
nine
different
developmental
stages,
variation
character
metabolite
contents
was
simultaneously
investigated
peel
pulp.
Furthermore,
principal
component
analysis
(PCA)
partial
least-squares
discriminant
(PLS-DA)
were
used
explore
profiles
samples.
Our
results
demonstrated
that
decrease
amino
acid,
accompanied
by
increase
sugars
organic
might
contribute
formation
betalains.
Notably,
one
four
potential
biomarker
metabolites,
citramalic
acid
be
related
formation.
The Crop Journal,
Journal Year:
2019,
Volume and Issue:
7(6), P. 857 - 866
Published: Oct. 21, 2019
Cold
tolerance
of
crop
plants
influences
survival
and
productivity
under
low-temperature
conditions.
Elucidation
molecular
mechanisms
underlying
low
temperature
could
be
helpful
in
breeding.
In
this
study,
we
used
integrated
transcriptomics
metabolomics
analyses
to
investigate
changes
gene/metabolite
activity
a
winter-hardy
wheat
cultivar
(cv.
Jing
411)
when
subjected
sold
stress.
The
223
metabolites
mainly
enriched
during
cold
acclimation
included
carbohydrates,
flavonoids,
amino
acids.
Eight
common
had
altered
abundance
following
freezing
treatment;
six
increased
two
decreased.
Transcriptome
analysis
revealed
that
29,066
genes
were
differentially
expressed
crowns
after
compared
the
non-acclimated
control.
Among
them,
745
up-regulated
treatment,
suggesting
substantial
change
expression
large
quantity
upon
which
impacts
on
modified
metabolites.
Integrated
gene
metabolite
profiles
abscisic
acid
(ABA)/jasmonic
(JA)
phytohormone
signaling
proline
biosynthesis
pathways
significantly
modulated
treatments.
Our
results
indicated
stress
induced
both
transcriptomes
metabolomes.
Critical
associated
with
ABA/JA
played
important
roles
regulating
wheat.
