Probing and Evaluating the Anion Binding Effects in One‐Walled meso‐Phenylboronic Acid Appended Calix[4]pyrrole (C4P) Based Supramolecular Receptors DOI
Ishfaq Ahmad Rather, Manawwer Alam, Rashid Ali

et al.

ChemistrySelect, Journal Year: 2023, Volume and Issue: 8(39)

Published: Oct. 19, 2023

Abstract Herein, binding affinities of one‐walled meso ‐phenylboronic acid functionalized calix[4]pyrroles (C4Ps, 3 a & b ) with diverse anions including spherical, linear, trigonal, and tetrahedral through UV‐Vis spectroscopy have successfully been revealed in acetonitrile solvent. The C4P derivative was newly synthesized from an easily accessible 3‐acetylphenylboronic via both conventional as well green protocols. Structure the final compound dipyrromethane (DPM) 2 , were unambiguously established by means 1 H‐NMR, 13 C‐NMR, HRMS spectral data. From outcomes titrations a/3 different (e. g., F − Cl Br I NO HSO 4 H PO CH COO SCN ), used their tetrabutylammonium (TBA) salts CN, : stoichiometric mode observed BindFit v0.5 Job plots. Overall, affinity receptor ( found higher comparison to presumably due more cooperative NH and/or OH hydrogen bonding interactions. On basis varied size halide ions, typical trend anion i. e ., >Cl >Br >I detected increase ions . Hopefully, these investigations C4P‐based ‐functionalized architectures will open new possibilities researchers generate even interesting artificial receptors based on vital boronic functionality, biological chemical importance is continuously motivating synthetic chemists worldwide.

Language: Английский

Synthesis of two novel fluorescein appended dipyromethanes (DPMs): Naked-eye chemosensors for fluoride, acetate and phosphate anions DOI
Shafieq Ahmad Wagay, Manawwer Alam, Rashid Ali

et al.

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1291, P. 135982 - 135982

Published: June 10, 2023

Language: Английский

Citations

11
Evaluation of naked-eye sensing and anion binding studies in meso-fluorescein substituted one-walled calix[4]pyrrole (C4P) DOI Creative Commons
Shafieq Ahmad Wagay, Ufana Riaz, Manawwer Alam

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(11), P. 7786 - 7796

Published: Jan. 1, 2024

Synthesis, anion binding studies and sensing properties of novel meso -fluorescien based one-walled calix[4]pyrrole has been reported.

Language: Английский

Citations

4
Probing and evaluating transmembrane chloride ion transport in double walled trifluorophenyl/phthalimide extended calix[4]pyrrole-based supramolecular receptors DOI
Ishfaq Ahmad Rather, Manzoor Ahmad, Pinaki Talukdar

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(24), P. 5950 - 5956

Published: Jan. 1, 2024

In this report, synthesis and ion-transport studies in two-walled calix[4]pyrroles have been revealed.

Language: Английский

Citations

2
Does Larger Cavity‐Size Really Help Bigger Anions to Bind? A Scrutiny on Core‐Expanded Calix[4]pyrroles and Their Properties DOI
Monalisa Giri,

Yashaswini Dash,

Tapas Guchhait

et al.

ChemPlusChem, Journal Year: 2023, Volume and Issue: 89(2)

Published: Oct. 13, 2023

Calix[4]pyrroles are an important class of oligopyrrolic macrocycles and have found applications in many diverse fields including anion recognition. To modulate the properties calix[4]pyrrole, several structural modifications realized. The core-expansion has attracted extra attention as it provides larger cavity-size compared to parent calix[4]pyrrole(s). This review highlights synthetic development various core-expanded calix[4]pyrroles their anion-binding properties. Emphasis is given changes binding observed with expanded versions calix[4]pyrrole(s) both solution solid states. calix[4]pyrrole do not always show higher affinities for anions anticipated. Rather, they display reduced anions. truncated form or asymmetric nature does probably allow access all available sites hence observed. receptors which contain a greater number somehow rigid preorganized apparently enhanced relative constants halide series indicate that enlarged molecules more beneficial largest iodide among others. However, most selectivity towards smallest fluoride over other studied.

Language: Английский

Citations

4
Expanded and contracted calixpyrroles: Insights towards syntheses and molecular recognition features DOI

Ishfaq Ahmad Rather,

Rashid Ali

Tetrahedron, Journal Year: 2024, Volume and Issue: 156, P. 133919 - 133919

Published: March 13, 2024

Language: Английский

Citations

1
Multifunctional Calix[4]Pyrrole Derivatives: Optimized Synthesis and a Dual-Action Study Targeting Tuberculosis and Oxidative Stress DOI
Nirali Parmar, Keyur Bhatt, Jaymin Parikh

et al.

Polycyclic aromatic compounds, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 24, 2024

The ongoing challenge of multidrug-resistant Mycobacterium tuberculosis underscores the urgent need for new therapeutic agents that address both (TB) and associated oxidative stress. This study explores synthesis bioactivity six novel calix[4]pyrrole derivatives fused with amino acids, using an optimized HATU DIPEA-mediated coupling method to enhance yield stability. These were subsequently assessed their antitubercular antioxidant activities. By incorporating particularly aromatic ones, into framework, aims investigate potential as dual-function candidates managing TB stress-related complications.

Language: Английский

Citations

0
Design and Synthesis of a one-walled Pyrene-Extended Calix[4]pyrrole: Selective Fluoride Anion Binding via Hydrogen Bonding DOI

Ahmad Hasan,

Ishfaq Ahmad Rather, Ufana Riaz

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141265 - 141265

Published: Dec. 1, 2024

Language: Английский

Citations

0
Novel synthesis and evaluation of anion-π interactions in one-walled meso-cyanophenyl substituted calix[4]pyrrole (C4P): Experimental and computational insights DOI

Ishfaq Ahmad Rather,

Manawwer Alam, Ufana Riaz

et al.

Journal of Molecular Structure, Journal Year: 2023, Volume and Issue: 1290, P. 135949 - 135949

Published: June 6, 2023

Language: Английский

Citations

1
Probing and Evaluating the Anion Binding Effects in One‐Walled meso‐Phenylboronic Acid Appended Calix[4]pyrrole (C4P) Based Supramolecular Receptors DOI
Ishfaq Ahmad Rather, Manawwer Alam, Rashid Ali

et al.

ChemistrySelect, Journal Year: 2023, Volume and Issue: 8(39)

Published: Oct. 19, 2023

Abstract Herein, binding affinities of one‐walled meso ‐phenylboronic acid functionalized calix[4]pyrroles (C4Ps, 3 a & b ) with diverse anions including spherical, linear, trigonal, and tetrahedral through UV‐Vis spectroscopy have successfully been revealed in acetonitrile solvent. The C4P derivative was newly synthesized from an easily accessible 3‐acetylphenylboronic via both conventional as well green protocols. Structure the final compound dipyrromethane (DPM) 2 , were unambiguously established by means 1 H‐NMR, 13 C‐NMR, HRMS spectral data. From outcomes titrations a/3 different (e. g., F − Cl Br I NO HSO 4 H PO CH COO SCN ), used their tetrabutylammonium (TBA) salts CN, : stoichiometric mode observed BindFit v0.5 Job plots. Overall, affinity receptor ( found higher comparison to presumably due more cooperative NH and/or OH hydrogen bonding interactions. On basis varied size halide ions, typical trend anion i. e ., >Cl >Br >I detected increase ions . Hopefully, these investigations C4P‐based ‐functionalized architectures will open new possibilities researchers generate even interesting artificial receptors based on vital boronic functionality, biological chemical importance is continuously motivating synthetic chemists worldwide.

Language: Английский

Citations

1