Synthesis and Medicinal Impacts of Novel 3,3′-Bihalocoumarins and Their Precursors, 7-Halocoumarin-3-acetic Acids DOI
Yasser Fakri Mustafa,

Marwa Mohammed Alshaher,

Duha Adnan Hassan

et al.

Russian Journal of Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: 51(2), P. 802 - 815

Published: April 1, 2025

Language: Английский

Food-Derived Micronutrients as Alleviators of Age-Related Dysfunction: A Dive into Their Effects and Cellular Mechanisms DOI Creative Commons
Yasser Fakri Mustafa,

Ayman Faris Faisal,

Marwa Mohammed Alshaher

et al.

Indian Journal of Clinical Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 13, 2025

Language: Английский

Citations

3
Synthesis of 7,8-dihydroxy-4-phenylbenzo[g]coumarins as potential multitarget anti-skin-aging candidates DOI
Yasser Fakri Mustafa

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1321, P. 139806 - 139806

Published: Aug. 26, 2024

Language: Английский

Citations

10
Digital alchemy: Exploring the pharmacokinetic and toxicity profiles of selected coumarin-heterocycle hybrids DOI Creative Commons
Nameer Mazin Zeki, Yasser Fakri Mustafa

Results in Chemistry, Journal Year: 2024, Volume and Issue: 10, P. 101754 - 101754

Published: Aug. 1, 2024

Language: Английский

Citations

9
Chili pepper: A delve into its nutritional values and roles in food-based therapy DOI Creative Commons

Ayman Faris Faisal,

Yasser Fakri Mustafa

Food Chemistry Advances, Journal Year: 2025, Volume and Issue: 6, P. 100928 - 100928

Published: Feb. 16, 2025

Language: Английский

Citations

1
Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review DOI
Yasser Fakri Mustafa

Indian Journal of Clinical Biochemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Language: Английский

Citations

1
Linearly ring-fused coumarins: A review of their cancer-fighting attributes DOI Creative Commons

Rana Naeem Jibroo,

Yasser Fakri Mustafa

Results in Chemistry, Journal Year: 2024, Volume and Issue: 8, P. 101611 - 101611

Published: June 1, 2024

Despite the up-to-date advancements in its treatment, cancer is still being harvested lives of millions people annually; this health threat necessitates exploring more potent agents that can effectively fight it. The class heterocycles known as coumarin, and natural synthetic derivatives are thought to be biomedically valuable. Coumarins have low side effects, outstanding selectivity, a straightforward design for maximum efficiency, various pharmacological actions. For these characteristics, coumarins continuously isolated from sources synthesized laboratories, alongside with examining them possible bioactivities. In addition garnering significant attention, coumarin has emerged valuable scaffold potentially important precursor development innovative anticancer medicines. Researchers working create new cancer-fighting coumarins, well investigating old ones. Integration two or cyclic moieties into single molecular framework might enhance existing effects perhaps provide entirely Numerous studies shown synergistic additive impact when fused where fusion may occur at coumarin-benzene coumarin-lactone. current paper explores detail how linearly ring-fused combat cancer. derivative number 42 was determined best among were reviewed. Compared 5-flourouracil, IC50 values against six cell lines promising. These 25.08, 13.42, 41.45, 28.43, 31.15, 13.08 μM SK-OV-3, HeLa, KYSE-30, AMN3, SKG, MCF-7, respectively. attribute obvious compared those reference, which following same order lines: 22.43, 13.37, 30.72, 24.89, 22.12, 12.42 μM. researchers conducted searches across multiple data repositories, such Scopus, Google Scholar, Web Science, PubMed. After conducting thorough analysis, authors found included 59 pertinent publications published by end 2023. reviewed help medicinal chemists manufacture functionally active leads using scaffolds been mentioned. knowledge derived offer substantial medical benefits short term powerful drugs could boost chemotherapeutics.

Language: Английский

Citations

7
3-mercaptocoumarins as potential bioactive candidates: From novel synthesis to comparative analysis DOI
Yasser Fakri Mustafa

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1320, P. 139657 - 139657

Published: Aug. 14, 2024

Language: Английский

Citations

7
Synthesis of novel skipped diene-3-halocoumarin conjugates as potent anticancer and antibacterial biocompatible agents DOI Creative Commons
Yasser Fakri Mustafa,

Duha Adnan Hassan,

Ayman Faris Faisal

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 11, P. 101846 - 101846

Published: Oct. 1, 2024

Language: Английский

Citations

5
Bioactive Phytochemicals from Bell Pepper (Capsicum annuum) By-Products DOI
Seok Tyug Tan, Seok Shin Tan, Chin Xuan Tan

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Linear pyranocoumarins are potential dazzling dancers between nature, chemistry, and clinical application DOI Creative Commons

Marwa Mohammed Alshaher,

Yasser Fakri Mustafa

Phytomedicine Plus, Journal Year: 2025, Volume and Issue: unknown, P. 100785 - 100785

Published: March 1, 2025

Language: Английский

Citations

0