Nano-drug Delivery System: a Promising Approach Against Breast Cancer DOI Creative Commons
Jonaid Ahmad Malik,

Jeba Ajgar Ansari,

Sakeel Ahmed

et al.

Therapeutic Delivery, Journal Year: 2023, Volume and Issue: 14(5), P. 357 - 381

Published: May 1, 2023

Breast cancer (BC) is among the most frequent malignancies women face around globe. Nanotherapeutics are constantly evolving to overcome limitations of conventional diagnostic and therapeutic approaches. Nanotechnology-based nanocarriers have a higher entrapment efficiency, low cytotoxicity, greater stability improved half-life than therapy. Nano-drug delivery systems pharmacokinetics pharmacodynamics parameters because nanomeric size. Currently, various nano-formulations in preclinical clinical settings for breast cancer, like polymeric nanoparticles, micelles, nanobodies, magnetic liposomes, niosomes, gold-nanoparticles, dendrimers carbon-nanotubes. This review highlights recent advancement developing nano-drug BC treatment. will open gateway researchers understand current approaches nano-formulation improving problems associated with

Language: Английский

Nanomaterials in anticancer applications and their mechanism of action - A review DOI
Chanchal Das, V. Ganesh Kumar, T. Stalin Dhas

et al.

Nanomedicine Nanotechnology Biology and Medicine, Journal Year: 2022, Volume and Issue: 47, P. 102613 - 102613

Published: Oct. 14, 2022

Language: Английский

Citations

56
Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care DOI Creative Commons
Alena Mazuráková, Lenka Koklesová, Marek Samec

et al.

The EPMA Journal, Journal Year: 2022, Volume and Issue: 13(2), P. 315 - 334

Published: April 14, 2022

Breast cancer incidence is actually the highest one among all cancers. Overall breast management associated with challenges considering risk assessment and predictive diagnostics, targeted prevention of metastatic disease, appropriate treatment options, cost-effectiveness approaches applied. Accumulated research evidence indicates promising anti-cancer effects phytochemicals protecting cells against malignant transformation, inhibiting carcinogenesis spread, supporting immune system increasing effectiveness conventional therapies, others. Molecular sub-/cellular mechanisms are highly complex affecting several pathways considered potent targets for advanced diagnostics cost-effective treatments. Demonstrated affects, therefore, clinically relevant improving individual outcomes might be applicable to primary (protection initial development), secondary potential disease tertiary (towards cascading complications) care. However, a detailed data analysis essential adapt algorithms individuals' patients' needs. Consequently, concepts patient stratification, prevention, treatments tailored individualized profile instrumental application natural substances improve overall benefiting affected individuals society at large.

Language: Английский

Citations

55
Nanoparticle-based materials in anticancer drug delivery: Current and future prospects DOI Creative Commons

Saniha Ajith,

Fares Almomani,

Abdelbary Elhissi

et al.

Heliyon, Journal Year: 2023, Volume and Issue: 9(11), P. e21227 - e21227

Published: Oct. 20, 2023

The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs body. However, these can lead undesirable side effects on healthy cells. To overcome this challenge and improve cell targeting, many nanocarriers have been developed deliver directly cancerous cells minimize tissues. majority research studies conclude that, using encapsulated much safer more effective alternative than delivering drug alone its free form. This review provides summary types mainly studied for delivery, namely: liposomes, polymeric micelles, dendrimers, magnetic nanoparticles, mesoporous gold carbon nanotubes quantum dots. In review, synthesis, applications, advantages, disadvantages, previous nanomaterials are discussed detail. Furthermore, future opportunities possible challenges translating materials into clinical applications also reported.

Language: Английский

Citations

33
Nanotechnology for ultrafast nucleic acid amplification DOI
Yiru Wang,

Yan Fei,

Tao Yang

et al.

Nano Today, Journal Year: 2023, Volume and Issue: 48, P. 101749 - 101749

Published: Jan. 6, 2023

Language: Английский

Citations

32
Nano-drug Delivery System: a Promising Approach Against Breast Cancer DOI Creative Commons
Jonaid Ahmad Malik,

Jeba Ajgar Ansari,

Sakeel Ahmed

et al.

Therapeutic Delivery, Journal Year: 2023, Volume and Issue: 14(5), P. 357 - 381

Published: May 1, 2023

Breast cancer (BC) is among the most frequent malignancies women face around globe. Nanotherapeutics are constantly evolving to overcome limitations of conventional diagnostic and therapeutic approaches. Nanotechnology-based nanocarriers have a higher entrapment efficiency, low cytotoxicity, greater stability improved half-life than therapy. Nano-drug delivery systems pharmacokinetics pharmacodynamics parameters because nanomeric size. Currently, various nano-formulations in preclinical clinical settings for breast cancer, like polymeric nanoparticles, micelles, nanobodies, magnetic liposomes, niosomes, gold-nanoparticles, dendrimers carbon-nanotubes. This review highlights recent advancement developing nano-drug BC treatment. will open gateway researchers understand current approaches nano-formulation improving problems associated with

Language: Английский

Citations

23