4D printing of shape memory polymer composites: A review on fabrication techniques, applications, and future perspectives

Journal of Manufacturing Processes, Journal Year: 2022, Volume and Issue: 81, P. 759 - 797

Published: July 25, 2022

Language: Английский

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Recent insights into polysaccharide-based hydrogels and their potential applications in food sector: A review

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 213, P. 987 - 1006

Published: June 12, 2022

Language: Английский

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Scaffold degradation in bone tissue engineering: An overview

International Biodeterioration & Biodegradation, Journal Year: 2023, Volume and Issue: 180, P. 105599 - 105599

Published: March 28, 2023

Language: Английский

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4D bioprinting of smart polymers for biomedical applications: recent progress, challenges, and future perspectives

Reactive and Functional Polymers, Journal Year: 2022, Volume and Issue: 179, P. 105374 - 105374

Published: Aug. 10, 2022

4D bioprinting is the next-generation additive manufacturing-based fabrication platform employed to construct intricate, adaptive, and dynamic soft hard tissue structures as well biomedical devices. It achieved by using stimuli-responsive materials, especially shape memory polymers (SMPs) hydrogels, which possess desirable biomechanical characteristics. In last few years, numerous efforts have been made printing community develop novel polymeric materials considering their perspective. This review presents an up-to-date overview of technology incorporating functionalities biomaterials focused approach towards different engineering regenerative medicine (TERM) applications. includes bone, cardiac, neural, cartilage, drug delivery systems, other high-value also addresses current limitations challenges in provide a basis for foreseeable advancements TERM applications that could be helpful successful utilization clinical settings.

Language: Английский

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Biomaterials / bioinks and extrusion bioprinting

Bioactive Materials, Journal Year: 2023, Volume and Issue: 28, P. 511 - 536

Published: June 27, 2023

Bioinks are formulations of biomaterials and living cells, sometimes with growth factors or other biomolecules, while extrusion bioprinting is an emerging technique to apply deposit these bioinks biomaterial solutions create three-dimensional (3D) constructs architectures mechanical/biological properties that mimic those native human tissue organs. Printed have found wide applications in engineering for repairing treating tissue/organ injuries, as well vitro modelling testing validating newly developed therapeutics vaccines prior their use humans. Successful printing subsequent rely on the formulated bioinks, including rheological, mechanical, biological properties, process. This article critically reviews latest developments bioprinting, focusing bioink synthesis characterization, influence Key issues challenges also discussed along recommendations future research.

Language: Английский

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A review on four-dimensional (4D) bioprinting in pursuit of advanced tissue engineering applications

Bioprinting, Journal Year: 2022, Volume and Issue: 27, P. e00203 - e00203

Published: March 30, 2022

Language: Английский

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Smart/stimuli-responsive hydrogels: State-of-the-art platforms for bone tissue engineering

Applied Materials Today, Journal Year: 2022, Volume and Issue: 29, P. 101560 - 101560

Published: June 22, 2022

Language: Английский

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Self-Healing Hydrogels: From Synthesis to Multiple Applications

ACS Materials Letters, Journal Year: 2023, Volume and Issue: 5(7), P. 1787 - 1830

Published: May 26, 2023

Due to the good reliability and long-term stability, self-healing hydrogels have emerged as promising soft materials for tissue engineering, smart wearable sensors, bioelectronics, energy storage devices. The mechanism depends on reversible chemical or physical cross-linking interactions. Self-healing with fascinating features (including mechanical performances, biocompatibility, conductivity, antibacterial ability, responsiveness, etc.) are being designed developed according practical application requirements. In this review, recent progress in their synthesis strategies multiple applications is summarized. Their involve processes a combination of two. include flexible strain supercapacitors, actuators, adhesives, wound healing, drug delivery, tumor treatment, 3D printing, etc. Finally, current challenges, future development, opportunities discussed.

Language: Английский

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Recent Advances in the Additive Manufacturing of Stimuli‐Responsive Soft Polymers

Advanced Engineering Materials, Journal Year: 2023, Volume and Issue: 25(21)

Published: Aug. 29, 2023

Stimuli‐responsive polymers (SRPs) are special types of soft materials, which have been extensively used for developing flexible actuators, robots, wearable devices, sensors, self‐expanding structures, and biomedical thanks to their ability change shapes functional properties in response external stimuli including light, humidity, heat, pH, electric field, solvent, magnetic field or combinations two more these stimuli. In recent years, additive manufacturing (AM) aka 3D printing technology SRPs, also known as 4D printing, has gained phenomenal attention different engineering fields, its unique develop complex, personalized, innovative undergo twisting, elongating, swelling, rolling, shrinking, bending, spiraling, other complex morphological transformations. Herein, an effort made provide insightful information about the AM techniques, type applications including, but not limited tissue engineering, bionics, construction, smart textiles. This article incorporates current challenges prospects, hoping basis utilization this fields. It is expected that amalgamation with SRPs would unparalleled advantages arenas.

Language: Английский

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Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions

Signal Transduction and Targeted Therapy, Journal Year: 2024, Volume and Issue: 9(1)

Published: July 1, 2024

The applications of hydrogels have expanded significantly due to their versatile, highly tunable properties and breakthroughs in biomaterial technologies. In this review, we cover the major achievements potential therapeutic applications, focusing primarily on two areas: emerging cell-based therapies promising non-cell modalities. Within context cell therapy, discuss capacity overcome existing translational challenges faced by mainstream therapy paradigms, provide a detailed discussion advantages principal design considerations for boosting efficacy as well list specific examples different disease scenarios. We then explore drug delivery, physical intervention therapies, other areas (e.g., bioadhesives, artificial tissues, biosensors), emphasizing utility beyond mere delivery vehicles. Additionally, complement our latest progress clinical application outline future research directions, particularly terms integration with advanced biomanufacturing This review aims present comprehensive view critical insights into selection both tailored meet requirements diverse diseases situations.

Language: Английский

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