Published: Jan. 1, 2024
Language: Английский
Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(8), P. 4086 - 4153
Published: Jan. 1, 2024
This review critically analyzes degradable biomedical elastomers, focusing on their degradation, synthesis, microstructure, and role in tissue repair. It guides experts balancing degradation with repair for improved applications.
Language: Английский
Citations
51
Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: 35(4), P. 482 - 500
Published: Jan. 8, 2024
Wound healing will be enhanced using structures with therapeutic effects. This study fabricated a novel nanofibrous scaffold for skin tissue regeneration coaxial structure polyglycerol sebacate (PGS)/platelet-rich plasma (PRP) was embedded in the core and two different compositions were selected shell; one group, polycaprolactone (PCL), other PGS/PCL blend used. The physical, mechanical behavior, drug delivery patterns, cell response of scaffolds evaluated. Results revealed that by adding PRP to PGS shell, fiber diameters decreased 260.8 ± 31.3 nm. It also water contact angle from 66° 32°, is ideal candidate attachment. release showed burst pattern first 30 min, followed continuous slow during day. Adding shell elastic modulus, its value reached about 500 kPa, which near modulus lead greater compatibility proliferation. Particularly, addition viability adhesion suitable morphology. Based on results, PGS-PRP/PGS-PCL dressing can enhance regeneration.
Language: Английский
Citations
11
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 727 - 727
Published: Jan. 16, 2025
While the traditional rubber industry faces severe pressure of environmental pollution and carbon emissions, bio-based biodegradable elastomers have become a hot topic in field drawn intensive research interest. Inspired by polyester resin, incorporating polyol or polycarboxylic acid as branching unit into aliphatic and/or introducing monomer with C=C bond to provide open-bond cross-linking fashion common vulcanization form three-dimensional network structures are two mainstream strategies for designing (BPEs). Both methods encounter more fewer problems, such poor mechanical thermal properties due easy hydrolysis ester space hinderance, potential harm remaining degraded small molecules olefin bonds. This article provides an overview recent endeavors aimed at addressing these challenges prospects probable future advancements field.
Language: Английский
Citations
1
Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12
Published: Aug. 15, 2024
Heart failure is a major health problem in which the heart unable to pump enough blood meet body’s needs. It progressive disease that becomes more severe over time and can be caused by variety of factors, including attack, cardiomyopathy valve disease. There are various methods cure this disease, has many complications risks. The advancement knowledge technology proposed new for diseases. One promising treatments tissue engineering. Tissue engineering field research aims create living tissues organs replace damaged or diseased tissue. goal improve cardiac function reduce need transplantation. This done using three important principles cells, biomaterials signals techniques cells such as electrospinning, hydrogel synthesis, decellularization, etc. diverse. Treating through still under development research, but it hoped there will no transplants invasive surgeries near future. In study, based on most recent years, we examine power treatment failure.
Language: Английский
Citations
5
Published: Jan. 1, 2025
Language: Английский
Citations
0
Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101280 - 101280
Published: Sept. 28, 2024
Language: Английский
Citations
1
Heliyon, Journal Year: 2024, Volume and Issue: 10(19), P. e38672 - e38672
Published: Sept. 28, 2024
Language: Английский
Citations
1
International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 7(2), P. 022004 - 022004
Published: Nov. 15, 2024
Abstract The inherent complexities of excitable cardiac, nervous, and skeletal muscle tissues pose great challenges in constructing artificial counterparts that closely resemble their natural bioelectrical, structural, mechanical properties. Recent advances have increasingly revealed the beneficial impact bioelectrical microenvironments on cellular behaviors, tissue regeneration, therapeutic efficacy for tissues. This review aims to unveil mechanisms by which electrical enhance regeneration functionality cells tissues, considering both endogenous cues from electroactive biomaterials exogenous stimuli external electronic systems. We explore synergistic effects these microenvironments, combined with structural guidance, using engineering scaffolds. Additionally, emergence micro/nanoscale bioelectronics has significantly broadened this field, facilitating intimate interactions between implantable across cellular, tissue, organ levels. These enable precise data acquisition localized modulation cell functionalities through intricately designed components according physiological needs. integration promises optimal outcomes, highlighting a growing trend developing living construct-bioelectronic hybrids restoring monitoring damaged Furthermore, we envision critical next-generation hybrids, focusing integrated fabrication strategies, development ionic conductive biomaterials, convergence biosensors.
Language: Английский
Citations
1
Published: Jan. 1, 2024
Language: Английский
Citations
0