Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)
Published: Dec. 26, 2024
Language: Английский
Biomaterials, Journal Year: 2024, Volume and Issue: 307, P. 122528 - 122528
Published: March 11, 2024
Language: Английский
Citations
41
Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 249, P. 114521 - 114521
Published: Jan. 14, 2025
Language: Английский
Citations
5
Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 14, 2025
Abstract Severe bone and cartilage defects caused by trauma are challenging to treat, often resulting in poor outcomes. An endogenous electric field (EnEF) is crucial for regeneration, making electrical materials a promising therapy. This review provides comprehensive overview of the role bioelectric signals cells, alongside recent advancements biomaterials, with particular emphasis on nanogenerators, piezoelectric materials, triboelectric scaffolds, zwitterionic hydrogels. It further investigates impact these biomaterials as well applications both exogenous stimulation (ES) mechanisms underlying ES‐induced cellular molecular responses. Finally, underscores future directions ES systems tissue engineering, emphasizing critical importance integrating structural integrity, mechanical properties, signal delivery into intelligent implantable scaffolds.
Language: Английский
Citations
2
Med-X, Journal Year: 2025, Volume and Issue: 3(1)
Published: March 4, 2025
Language: Английский
Citations
2
Nano Energy, Journal Year: 2024, Volume and Issue: 126, P. 109569 - 109569
Published: April 9, 2024
Magnetoelectric (ME) materials have emerged as promising candidates for a wide range of biomedical applications due to their unique ability couple and manipulate both magnetic electric signals. This comprehensive review provides an overview the recent advancements potential MEs in various areas biomedicine. Inspired by Mary Shelley's "Frankenstein," introduction (Section 1) highlights ethical considerations scientific exploration while showcasing benefits ME background human well-being longevity. Then, context, key fundamental concepts are addressed, with special focus on piezoelectric biological tissues that can be sensorized/actuated through 2). Applications related energy supply body 3), sensing 4), other 5) such tissue engineering, cancer therapy, drug delivery, antimicrobial presented, discussed, technologically outlined following sections work. In end, subjective joint opinion is given about advantages, limitations, opportunities, future research directions this 130-year-old field. Can come out technological bridge between energy, life?
Language: Английский
Citations
14
Deleted Journal, Journal Year: 2024, Volume and Issue: 2(3)
Published: May 24, 2024
Abstract Despite extensive research on piezoelectric polymers since the discovery of poly(vinylidene fluoride) (PVDF) in 1969, fundamental physics polymer piezoelectricity has remained elusive. Based classic principle piezoelectricity, should originate from polar crystalline phase. Surprisingly, crystal contribution to strain coefficient d 31 is determined be less than 10%, primarily owing difficulty changing molecular bond lengths and angles. Instead, >85% Poisson's ratio, which closely related oriented amorphous fraction (OAF) uniaxially stretched films semicrystalline ferroelectric (FE) polymers. In this perspective, structure–piezoelectric property relationship revealed using PVDF‐based FE as a model system. melt‐processed polymers, OAF often present links lamellae isotropic fraction. Molecular dynamics simulations demonstrate that electrostrictive conformation transformation chains induces polarization change upon application either stress (the direct effect) or an electric field converse effect). Meanwhile, relaxor‐like secondary crystals (SC ), are favored grow extended‐chain (ECC) structure, can further enhance piezoelectricity. However, ECC structure difficult achieve PVDF homopolymers without high‐pressure crystallization. We have discovered high‐power ultrasonication effectively induce SC improve its performance. Finally, we envision mechanism also applicable for other such odd‐numbered nylons biopolymers.
Language: Английский
Citations
8
Bioengineering, Journal Year: 2024, Volume and Issue: 11(8), P. 776 - 776
Published: July 31, 2024
The regenerative capacity of the peripheral nervous system is limited, and nerve injuries often result in incomplete healing poor outcomes even after repair. Transection that induce a gap necessitate microsurgical intervention; however, current gold standard repair, autologous graft, frequently results functional recovery. Several interventions have been developed to augment surgical repair nerves, application biomaterials, local delivery bioactive substances, electrical stimulation, allografts are among most promising approaches enhance innate across gap. Biocompatible polymers with optimized degradation rates, topographic features, other functions provided by their composition incorporated into novel conduits (NCs). Many these allow for drugs, neurotrophic factors, whole cells locally sites, mitigating adverse effects limit systemic use. stimulation repaired nerves perioperative period has shown benefits recovery human trials, biomaterials show promise preclinical models. use acellular (ANAs) circumvents morbidity donor harvest necessitated autografts, improvements tissue-processing techniques may more readily available cost-effective options. Each aid neural regeneration when applied independently, differing forms, benefits, methods present ample opportunity synergistic combination.
Language: Английский
Citations
8
Advanced Materials Technologies, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Abstract Piezoelectric composites have received widespread attentions in the fields of biomedicine and vitro wearable devices due to their ability convert mechanical forces into charge signals. The preparation piezoelectric with complex structures through 3D printing technology can not only effectively improve output, but also enable customized therapeutic applications. This paper first introduces types reviews commonly used preparation, analyzing advantages disadvantages each technology. Then, state‐of‐the‐art biomedical applications composites, including drug sustained‐release, wound healing promotion, bone tissue cells growth promoting, neurorehabilitation stimulating, ultrasonic diagnosis, vivo biosensing sensing, are emphasized. Finally, main factors affecting printed outlooked, an in‐depth discussion on challenges toward analyzed. review is believed provide some fundamental knowledge composites.
Language: Английский
Citations
7
Polymer Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 15, 2024
Conventional plastics pose significant environmental and health risks across their life cycle, driving intense interest in sustainable alternatives. Among these, polyhydroxyalkanoates (PHAs) stand out for biocompatibility, degradation characteristics, diverse applications. Yet, challenges like production cost, scalability, limited chemical variety hinder widespread adoption, impacting material selection design. This review examines PHA research through the lens of classical materials tetrahedron, exploring property-structure-processing-performance (PSPP) relationships. By analyzing recent literature addressing current limitations, we gain valuable insights into development. Despite challenges, remain optimistic about role PHAs transitioning towards a circular plastic economy, emphasizing need further to unlock full potential.
Language: Английский
Citations
4
Molecules, Journal Year: 2025, Volume and Issue: 30(1), P. 179 - 179
Published: Jan. 4, 2025
Conducting polymers represent a crucial class of functional materials with widespread applications in diverse fields. Among these, poly(3,4-ethylenedioxythiophene) (PEDOT) and its derivatives have garnered significant attention due to their distinctive optical, electronic, magnetic properties, as well exceptional tunability. These properties often exhibit intricate interdependencies, manifesting synergistic, concomitant, or antagonistic relationships. In optics, PEDOTs are renowned for high transparency unique photoelectric responses. From an electrical perspective, they display conductivity, thermoelectric, piezoelectric performance, along notable electrochemical activity stability, enabling wide array electronic applications. terms demonstrate outstanding electromagnetic shielding efficiency microwave absorption capabilities. Moreover, these can be precisely tailored through molecular structure modifications, chemical doping, composite formation suit various application requirements. This review systematically examines the mechanisms underlying optoelectromagnetic PEDOTs, highlights tunability, outlines prospective research directions. By providing critical theoretical insights technical references, this aims advance landscape PEDOTs.
Language: Английский
Citations
0