Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration DOI Creative Commons
Hui Zhu, Ying Wang, Siyuan Xu

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Dec. 26, 2024

Language: Английский

Quantum Computing in the Realm of Neurosurgery DOI
Ali A. Mohamed, Emma Sargent, Camberly Moriconi

et al.

World Neurosurgery, Journal Year: 2024, Volume and Issue: 193, P. 8 - 14

Published: Oct. 21, 2024

Language: Английский

Citations

2
Piezoelectric silk fibroin nanofibers: structural optimization to enhance piezoelectricity and biostability for neural tissue engineering DOI

Lu Jin,

Youyi Tai, Jin Nam

et al.

Nano Energy, Journal Year: 2024, Volume and Issue: unknown, P. 110367 - 110367

Published: Oct. 1, 2024

Language: Английский

Citations

2
Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications DOI Open Access
Maksym Krutko, Holly M. Poling,

Andrew Bryan

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 19, 2024

Abstract This study investigates bioelectric stimulation’s role in tissue regeneration by enhancing the piezoelectric properties of tissue-engineered grafts using annealed poly(vinylidene fluoride-trifluoroethylene) (PVDF-TrFE) scaffolds. Annealing at temperatures 80°C, 100°C, 120°C, and 140°C was assessed for its impact on material physiological utility. Analytical techniques such as Differential Scanning Calorimetry (DSC), Fourier-Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD) revealed increased crystallinity with higher annealing temperatures, peaking β-phase content 140°C. Electron Microscopy (SEM) showed that scaffolds had enhanced lamellar structures, porosity, maximum response. Mechanical tests indicated improved elastic modulus, tensile strength, substrate stiffness, aligning these soft tissues. In vitro assessments Schwann cells demonstrated favorable responses, cell proliferation, contraction, extracellular matrix attachment. Additionally, genes linked to production, vascularization, calcium signaling were upregulated. The foreign body response C57BL/6 mice, evaluated through Hematoxylin Eosin (H&E) Picrosirius Red staining, no differences between scaffold groups, supporting potential future functional evaluation group repair.

Language: Английский

Citations

1
Advances in biomaterial-based tissue engineering for peripheral nerve injury repair DOI
Xinlei Yao,

Tong Xue,

B. Chen

et al.

Bioactive Materials, Journal Year: 2024, Volume and Issue: 46, P. 150 - 172

Published: Dec. 13, 2024

Language: Английский

Citations

1
Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration DOI Creative Commons
Hui Zhu, Ying Wang, Siyuan Xu

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Dec. 26, 2024

Language: Английский

Citations

1