Stimuli-activatable nanomedicine meets cancer theranostics

Theranostics, Journal Year: 2023, Volume and Issue: 13(15), P. 5386 - 5417

Published: Jan. 1, 2023

Stimuli-activatable strategies prevail in the design of nanomedicine for cancer theranostics.Upon exposure to endogenous/exogenous stimuli, stimuli-activatable could be self-assembled, disassembled, or functionally activated improve its biosafety and diagnostic/therapeutic potency.A myriad tumor-specific features, including a low pH, high redox level, overexpressed enzymes, along with exogenous physical stimulation sources (light, ultrasound, magnet, radiation) have been considered nano-medicinal products.Recently, novel stimuli explored elegant designs emerged nanomedicine.In addition, multi-functional theranostic has employed imaging-guided image-assisted antitumor therapy.In this review, we rationalize development clinical pressing needs.Stimuli-activatable self-assembly, disassembly functional activation approaches developing realize better efficacy are elaborated state-of-the-art advances their structural detailed.A reflection, status, future perspectives provided.

Language: Английский

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Green Synthesis of Cobalt Ferrite Nanoparticles: An Emerging Material for Environmental and Biomedical Applications

Journal of Nanomaterials, Journal Year: 2023, Volume and Issue: 2023, P. 1 - 15

Published: Feb. 6, 2023

Research and utilization of nanotechnology are growing exponentially in every aspect life. The constant growth applications for magnetic nanoparticles, specifically nanoferrites, attracted many researchers. Among them, nanocobalt ferrite is the most crucial studied nanoparticle. Environmentally benign synthetic methods became necessary to minimize environmental occupational hazards. Green synthesis approaches science technology now widely applied nanomaterials. Herein, we reviewed recent advances synthesizing ferrites their composites using various scientific search engines. Subsequently, were discussed, such as (treatment water/wastewater, photocatalytic degradation dyes, nanosorbent remediation) biomedical (nanobiosensors cancer diagnosis at primary stage, effective targeted drug delivery, resonance imaging, hyperthermia, potential candidates against microbial infections). This review offers comprehensive knowledge on how choose appropriate natural resources green benefits this approach compared conventional methods.

Language: Английский

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The Use of Metallic Nanoparticles in Wound Healing: New Perspectives

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(23), P. 15376 - 15376

Published: Dec. 6, 2022

Chronic wounds represent a challenge for the health area, as they directly impact patients' quality of life and threat to public global economy due their high cost treatment. Alternative strategies must be developed cost-effective targeted In this scenario, emerging field nanobiotechnology may provide an alternative platform develop new therapeutic agents chronic wound healing process. This manuscript aims demonstrate that application metallic nanoparticles (gold, silver, copper, zinc oxide) opened chapter in treatment wounds, have different properties such drug delivery, antimicrobial activity, acceleration. Furthermore, (NPs) produced through green synthesis ensure less toxicity biological tissues, greater safety applicability, other than adding effects NPs with those extracts.

Language: Английский

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Biomedical applications of biodegradable polycaprolactone-functionalized magnetic iron oxides nanoparticles and their polymer nanocomposites

Colloids and Surfaces B Biointerfaces, Journal Year: 2023, Volume and Issue: 227, P. 113342 - 113342

Published: May 11, 2023

Language: Английский

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Preparation of pH-responsive magnetic nanocomposite hydrogels based on k-carrageenan/chitosan/silver nanoparticles: Antibacterial carrier for potential targeted anticancer drug delivery

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 246, P. 125546 - 125546

Published: June 23, 2023

Language: Английский

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A Comprehensive Review on the Synthesis and Therapeutic Potential of Cobalt Ferrite (CoFe₂O₄) Nanoparticles

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 1, 2025

Abstract The field of nanotechnology is witnessing a remarkable surge in research and applications across various domains, showcasing exponential growth. Considerable progress has been made the advancement novel techniques for synthesis magnetic nanoparticles (MNPs) with enhanced features. Within this realm, spinel nanoferrites have gained attention due to their significant characteristics, such as increased responsiveness, improved stability biological environments, ease synthesis, surface modification capabilitiesmaking them highly applicable diverse domains. Cobalt ferrite are considered one most investigated MNPs within range. Owing distinct physical, chemical, properties, CoFe₂O₄ NPs emerged potential candidates realm biomedical applications, highlighting suitability innovative healthcare solutions. For considerable period, limited effectiveness current cancer treatment methods chemotherapy radiotherapy posed many challenges side effects. This prompted need development new technologies by incorporating functional nanomaterials that showed substantial efficacy effective strategies treating cancer. comprehensive review, therefore, introduces prominent synthesizing these ferrites particularly focusing on anticancerand antibacterial properties exhibited cobalt nanoparticles.

Language: Английский

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Investigation of magnetic and structural properties of Dy-substituted Mn-Zn ferrite nanoparticles for hyperthermia applications

Journal of Sol-Gel Science and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Language: Английский

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Recent advances in zinc ferrite (ZnFe₂O₄) based nanostructures for magnetic hyperthermia applications

Chemical Communications, Journal Year: 2023, Volume and Issue: 59(81), P. 12065 - 12090

Published: Jan. 1, 2023

Zinc ferrite based nanostructures for magnetic hyperthermia applications.

Language: Английский

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Green synthesis of cobalt ferrite and Mn doped cobalt ferrite nanoparticles: Anticancer, antidiabetic and antibacterial studies

Journal of Trace Elements in Medicine and Biology, Journal Year: 2023, Volume and Issue: 80, P. 127292 - 127292

Published: Aug. 27, 2023

Language: Английский

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Assessment of chitosan-coated zinc cobalt ferrite nanoparticle as a multifunctional theranostic platform facilitating pH-sensitive drug delivery and OCT image contrast enhancement

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 654, P. 123999 - 123999

Published: March 13, 2024

Language: Английский

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