Metal coordination bond and rough interface enhanced triboelectric nanogenerator aiming for multiple complex conditions DOI

Zhenyang Li,

Chenyu Li,

Yue Xiao

et al.

Nano Energy, Journal Year: 2024, Volume and Issue: unknown, P. 110532 - 110532

Published: Dec. 1, 2024

Language: Английский

Biosynthetic small molecule antigens mimics medicated lateral flow immunoassay for mycotoxin Fumonisin B1 using nanobody fusion proteins DOI

Chong Cai,

Yuheng Xia,

Yuanzhen Guo

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 487, P. 137194 - 137194

Published: Jan. 11, 2025

Language: Английский

Citations

2
Multifunctional Hydrogel Microneedles (HMNs) in Drug Delivery and Diagnostics DOI Creative Commons
Hossein Omidian, Sumana Dey Chowdhury

Gels, Journal Year: 2025, Volume and Issue: 11(3), P. 206 - 206

Published: March 15, 2025

Hydrogel microneedles (HMNs) have emerged as a transformative platform for minimally invasive drug delivery and biosensing, offering enhanced bioavailability, controlled release, real-time biomarker detection. By leveraging swelling hydrogels, nanomaterial integration, stimuli-responsive properties, HMNs provide precision medicine capabilities across diverse therapeutic diagnostic applications. However, challenges remain in mechanical stability, hydrogel-based MNs must balance flexibility with sufficient strength skin penetration. Drug retention release require optimization to prevent premature diffusion ensure sustained effects. Additionally, biosensing accuracy is influenced by variability interstitial fluid extraction signal transduction. Clinical translation hindered regulatory hurdles, scalability concerns, the need extensive safety validation human trials. This review critically examines key materials, fabrication techniques, functional testing frameworks of while addressing these limitations. Furthermore, we explore future research directions smart wearable MNs, AI-assisted hybrid drug–device platforms optimize transdermal medicine. Overcoming barriers will drive clinical adoption HMNs, paving way next-generation patient-centered therapeutics diagnostics.

Language: Английский

Citations

1
Innovative Nanozyme-Based Detection Methods for Biomarkers in Interstitial Fluid DOI

Jiuhong Zhao,

Junjie Tian, Xiaoyu Zhang

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118248 - 118248

Published: April 1, 2025

Language: Английский

Citations

0
Metal coordination bond and rough interface enhanced triboelectric nanogenerator aiming for multiple complex conditions DOI

Zhenyang Li,

Chenyu Li,

Yue Xiao

et al.

Nano Energy, Journal Year: 2024, Volume and Issue: unknown, P. 110532 - 110532

Published: Dec. 1, 2024

Language: Английский

Citations

0