Iranian Polymer Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 20, 2024
Language: Английский
Iranian Polymer Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 20, 2024
Language: Английский
Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2024, Volume and Issue: unknown
Published: July 13, 2024
Language: Английский
Citations
11Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 220, P. 119234 - 119234
Published: July 18, 2024
Language: Английский
Citations
6Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114019 - 114019
Published: Jan. 1, 2025
Language: Английский
Citations
0Environmental Nanotechnology Monitoring & Management, Journal Year: 2025, Volume and Issue: unknown, P. 101061 - 101061
Published: March 1, 2025
Language: Английский
Citations
0Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 142209 - 142209
Published: March 1, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142648 - 142648
Published: March 1, 2025
Language: Английский
Citations
0Reaction Kinetics Mechanisms and Catalysis, Journal Year: 2025, Volume and Issue: unknown
Published: April 13, 2025
Language: Английский
Citations
0Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 39, P. 101321 - 101321
Published: Sept. 1, 2024
Language: Английский
Citations
3Topics in Catalysis, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 13, 2025
Language: Английский
Citations
0Journal of Nanotechnology, Journal Year: 2025, Volume and Issue: 2025(1)
Published: Jan. 1, 2025
Purpose: This study presents a novel and sustainable approach to cancer therapy by combining halloysite nanotubes (HNTs), green‐synthesized copper oxide (CuO) nanoparticles, curcumin (CUR). We demonstrate that the green synthesis of CuO when combined with CUR incorporated into HNTs, enhances delivery anticancer effects CUR. innovative complex could address some critical limitations current therapies such as poor pharmacokinetics drug resistance providing controlled release mechanism leveraging benefits combination therapy. Methods: synthesized using lemon peel extract used this formulate HNT (CHC). Comprehensive characterization was conducted UV‐visible spectroscopy, scanning electron microscopy‐energy‐dispersive X‐ray spectroscopy (SEM–EDX), diffraction (XRD), thermogravimetric analysis (TGA), Fourier‐transform infrared (FTIR). also examined kinetics formulation. In vitro experiments were performed evaluate on HMVII, HepG2, MCF‐7 cell lines. addition, an in silico docking assessment 10 ns molecular dynamics simulation determine interaction between HNTs. Results: The HNTs loaded showed loading efficiency 3%–5% encapsulation 15%–20%. Drug best described Hixson–Crowell model for CHC‐50 CHC‐20, R 2 = 0.9897 0.9900 respectively. CHC‐10 fit Higuchi ( 0.8838), while free Korsmeyer–Peppas 0.9212). formulations demonstrated significant across all tested lines, showing lowest IC 50 value 10.43 μg/mL. CHC exhibited enhanced maintained activity compared MCF‐7, HMVII lower IC50 values after UV exposure. Molecular revealed CUR–HNT binding score −3.803, remaining stable over simulation. Conclusion: demonstrates successful integration nanoparticles CUR‐loaded formulation, coupled complex’s stability, suggest potential improving treatment outcomes. innovative, addresses key therapies, potentially offering more effective patient‐friendly treatments reduced side effects. Our findings pave way further development targeted, environmentally conscious therapies.
Language: Английский
Citations
0