Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Psychological Medicine, Journal Year: 2025, Volume and Issue: 55
Published: Jan. 1, 2025
Abstract To optimize the antidepressant efficacy of repetitive transcranial magnetic stimulation (rTMS), it is important to examine impact brain state during therapeutic rTMS. Evidence suggests that can modulate brain’s response stimulation, potentially diminishing if left uncontrolled or enhancing with inexpensive psychological other non-pharmacological methods. Thus, we conducted a PRISMA-ScR-based scoping review pool studies administering rTMS and PubMed Web Science databases were searched from inception 10 July 2024. Inclusion criteria: neuropsychiatric patients underwent rTMS; assessed depressive symptom severity; tasks interventions administered rTMS, did not include wash-out period. Of 8,442 studies, 20 combined aerobic exercise, bright light therapy, cognitive training reactivation, psychotherapy, sleep deprivation, psychophysical task. Meta-analyses using random effects models based on change scores standardized scales. The effect size was large for pretest-posttest comparisons (17 Hedges’ g = −1.91, (standard error) SE 0.45, 95% (confidence interval) CI −2.80 −1.03, p < 0.01); medium when compared active combinations sham plus methods (8 −0.55, 0.14, −0.82 −0.28, non-significant (4 0.96). Attempts administer show promise but have yet outperformed alone.
Language: Английский
Citations
0
Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Substance use disorders (SUDs) and Gambling Disorder (GD) are addictive diseases with a chronic course. Due to the limited efficacy of conventional treatments, there is growing interest in alternative approaches targeting altered neural circuits underlying these disorders. Deep Transcranial Magnetic Stimulation (dTMS) has emerged as promising neuromodulation technique capable reaching deep bilateral brain regions. However, no definite recommendation for its addiction treatment exists. This study systematically reviewed quantitatively analyzed dTMS effects SUDs GD. Following PRISMA guidelines, we screened four electronic databases up February 2024 selected relevant English-written original research articles. Seventeen papers were included systematic review. As only minority studies employed sham-controlled design, ran meta-analysis on subset 12 studies, computing pre-post real stimulation standardized mean change (SMCC) effect size, using self-reported craving scores dependent variable. The results showed significant large reducing (SMCC = - 1.26, 95% CI [-1.67, 0.86], p <.001). High heterogeneity across was found at both quantitative qualitative levels. Results provide preliminary evidence supporting effectiveness treatment. Current limitations future directions critically discussed, highlighting need further rigorous refine therapeutic potential develop consensus-based guidelines clinical application.
Language: Английский
Citations
0
Brain stimulation, Journal Year: 2024, Volume and Issue: 17(2), P. 434 - 443
Published: March 1, 2024
Transcranial direct current stimulation (tDCS) targeting the prefrontal cortex has emerged as a valuable tool in psychiatric research. Understanding impact of affective states, such stress at time stimulation, on efficacy tDCS is crucial for advancing interventions. Stress-primed tDCS, wherein used priming agent, potential to modulate neural plasticity and enhance cognitive functions, particularly emotional working memory. However, prior research using stress-primed focused solely non-emotional memory performance, yielding mixed results. In this sham-controlled study, we addressed gap by investigating effects bifrontal (active versus sham) both performance. The study was conducted 146 healthy individuals who were randomly assigned four experimental groups. Trier Social Stress Test (TSST) or control variant test induce state. results showed that significantly enhanced updating content memory, evidenced improved accuracy. Notably, no significant found These findings highlight importance an individual's state shaping their response especially context
Language: Английский
Citations
3
Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 13
Published: Jan. 9, 2023
Deep repetitive transcranial magnetic stimulation (Deep TMS™) was recently cleared by the FDA as a short-term treatment for smoking cessation. However, it is unknown which participants are more likely to benefit from treatment.We evaluated data published randomized controlled trial of 262 22-70 years old that led clearance characterize demographic and history factors moderate TMS efficacy. The current analysis included 75 completers in active group 94 sham group.We found younger than 40 had four times quit rate those older 40. Additionally, who following smoked 10 less non-quitters. Moreover, Caucasian two African-American participants. Strikingly, with 12 education 7 education.Three weeks has higher addiction younger, educated, extensive history. Participants older, may need longer course and/or combined modalities. Potential reasons be related challenges inducing neuronal modifications greater physical psychological dependence. Further investigation warranted.
Language: Английский
Citations
5
Frontiers in Psychiatry, Journal Year: 2023, Volume and Issue: 14
Published: April 14, 2023
Addiction is a persistent, recurring condition characterized by repeated relapses despite the desire to control drug use or maintain sobriety. The attainment of abstinence hindered persistent maladaptive drug-associated memories, which drive drug-seeking and behavior. This article examines preliminary evidence supporting combination non-invasive brain stimulation (NIBS) techniques memory editing (or reconsolidation) interventions as add-on forms treatment for individuals with substance-related disorders (SUD). Studies have shown that NIBS can modestly reduce craving through improved cognitive other undetermined reasons. Memory reconsolidation, process previously consolidated trace be made labile again, potentially erase significantly weaken SUD memories underpinning propensity relapse. approach conveys enthusiasm while also emphasizing importance managing boundary conditions null results found on fear reconsolidation. Recent studies, align state-dependency activity-selectivity hypotheses, behavioral holds promise treating reducing self-reported physiological aspects craving. Effective long-term outcomes this procedure require better identification critical deeper understanding mechanisms underlying reconsolidation overcoming any destabilized memories. will enable personalized unique needs individual patients.
Language: Английский
Citations
5
Expert Review of Neurotherapeutics, Journal Year: 2024, Volume and Issue: 24(4), P. 343 - 360
Published: Feb. 13, 2024
Introduction Borderline personality disorder (BPD) is a severe mental characterized by emotion dysregulation, impulsivity, neuropsychological impairment, and interpersonal instability, presenting with multiple psychiatric comorbidities, functional disability reduced life expectancy due suicidal behaviors.
Language: Английский
Citations
1
The American Journal of Psychoanalysis, Journal Year: 2024, Volume and Issue: 84(2), P. 285 - 310
Published: June 1, 2024
Language: Английский
Citations
1
Brain Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 683 - 683
Published: July 8, 2024
Schizophrenia is a chronic psychiatric disorder severely affecting patients’ functioning and quality of life. Unlike positive symptoms, cognitive impairment negative symptoms cannot be treated pharmacologically represent consistent predictors the illness’s prognosis. Cognitive remediation (CR) interventions have been applied to target these symptoms. Brain stimulation also provides promising yet preliminary results in reducing whereas its effect on remains heterogeneous. Here, we combined intermittent theta burst (iTBS) with CR improve schizophrenia spectrum patients. One hundred eligible patients were invited, twenty-one participated. We randomized them into four groups, manipulating condition (real vs. sham) (no training training). delivered fifteen iTBS sessions over left dorsolateral prefrontal cortex for three weeks, followed (or not) by 50 min training. Consensus-based clinical assessment was administered at baseline after treatment, plus follow-ups occurring one, three, six months intervention. Mixed-model analyses run symptom scores. The findings highlighted marginal modulation improved isolated functions. herein discuss limitations strengths methodological approach.
Language: Английский
Citations
1
Psychiatric Clinics of North America, Journal Year: 2024, Volume and Issue: 47(2), P. 355 - 365
Published: March 15, 2024
Language: Английский
Citations
1
World Journal of Clinical Cases, Journal Year: 2024, Volume and Issue: 12(10), P. 1742 - 1749
Published: April 2, 2024
Speech disorders have a substantial impact on communication abilities and quality of life. Traditional treatments such as speech psychological therapies frequently demonstrate limited effectiveness patient compliance. Transcranial electrical stimulation (TES) has emerged promising non-invasive treatment to improve neurological functions. However, its in enhancing language functions serum neurofactor levels individuals with requires further investigation.
Language: Английский
Citations
1