Objective:
The
neurocognitive
risk
mechanisms
predicting
divergent
outcomes
likely
differ
between
men
and
women
who
use
cannabis
recreationally.
Increasingly,
the
of
descriptive
distributions
including
ex-Gaussian
has
been
applied
to
draw
stronger
inferences
about
health
in
clinical
populations.
current
project
examines
whether
long
tail
reaction
times
(RTs)
a
distribution,
as
characterized
by
parameter
tau
which
may
represent
difficulty
with
regulation
arousal,
predicts
problematic
6
months
later
those
recreationally,
sex
moderates
these
prospective
associations.
Method:
Young
adults
(ages
18-30,
mean
age
20.5
years,
N
=159,
57.2%
women,
69.2%
Caucasian)
recreationally
used
either
occasionally
(at
least
once
per
month)
or
frequently
(three
more
week)
completed
Stroop
Color-Word
Task
at
baseline.
Ex-Gaussian
was
estimated
for
each
participant.
Self-report
hazardous
(CUDIT-R)
dysregulation
negative
(DERS)
positive
emotions
(DERS-Positive)
were
obtained
baseline
6-month
follow-up.
Results:
For
larger
baseline,
being
man
(but
not
woman)
associated
increased
regulating
concurrently
(b
=
-0.01,
F
(1,159)
5.48,
p
0.02),
six
-0.007,
4.42,
0.037)
after
controlling
use.
Conclusions:
Excessively
RTs
during
cognitive
performance
help
characterize
use,
contributes
understanding
between-sex
heterogeneity
pathways
towards
disorders.
Comprehensive Psychiatry,
Journal Year:
2024,
Volume and Issue:
130, P. 152460 - 152460
Published: Feb. 5, 2024
Addictions
have
recently
been
classified
as
substance
use
disorder
(SUD)
and
behavioral
addiction
(BA),
but
the
concept
of
BA
is
still
debatable.
Therefore,
it
necessary
to
conduct
further
neuroscientific
research
understand
mechanisms
same
extent
SUD.
The
present
study
used
machine
learning
(ML)
algorithms
investigate
neuropsychological
neurophysiological
aspects
addictions
in
individuals
with
internet
gaming
(IGD)
alcohol
(AUD).
We
developed
three
models
for
distinguishing
IGD
from
those
AUD,
healthy
controls
(HCs),
AUD
HCs
using
ML
algorithms,
including
L1-norm
support
vector
machine,
random
forest,
logistic
regression
(LR).
Three
distinct
feature
sets
were
model
training:
a
unimodal-electroencephalography
(EEG)
set
combined
sensor-
source-level
feature;
unimodal-neuropsychological
(NF)
included
sex,
age,
depression,
anxiety,
impulsivity,
general
cognitive
function,
multimodal
(EEG
+
NF)
set.
LR
classification
outperformed
other
(accuracy:
0.712).
important
features
selected
by
highlighted
that
group
had
differential
delta
beta
source
connectivity
between
right
intrahemispheric
regions
sensor-level
EEG
activities.
Among
NFs,
sex
age
good
performance.
Using
techniques,
we
demonstrated
similarities
differences
(a
BA)
SUD).
Journal of Behavioral Addictions,
Journal Year:
2024,
Volume and Issue:
13(1), P. 177 - 190
Published: March 7, 2024
The
high
prevalence
of
internet
addiction
(IA)
has
become
a
worldwide
problem
that
profoundly
affects
people's
mental
health
and
executive
function.
Empirical
studies
have
suggested
trait
anxiety
(TA)
as
one
the
most
robust
predictors
addictive
behaviors.
present
study
investigated
neural
socio-psychological
mechanisms
underlying
association
between
TA
IA.
Firstly,
we
tested
correlation
Then
longitudinal
influence
on
IA
using
linear
mixed
effect
(LME)
model.
Secondly,
connectome-based
predictive
modeling
(CPM)
was
employed
to
explore
neuromarkers
TA,
whether
identified
can
predict
Lastly,
stressful
life
events
default
mode
network
(DMN)
were
considered
mediating
variables
relationship
A
significant
positive
found
group
demonstrated
higher
across
time.
CPM
results
revealed
functional
connectivity
cognitive
control
emotion-regulation
circuits
DMN
significantly
correlated
with
TA.
Furthermore,
Notably,
all
validated
in
an
independent
sample.
mediation
mediated
Findings
facilitate
deeper
understanding
linking
provide
new
directions
for
developing
psychological
interventions.
Brain and Behavior,
Journal Year:
2025,
Volume and Issue:
15(3)
Published: Feb. 28, 2025
ABSTRACT
Purpose
The
relationship
between
attentional
bias
and
substance
use
patterns
cravings
in
addiction
is
well
documented.
However,
the
connections
relapse
remain
unclear.
This
systematic
review
aims
to
examine
synthesize
longitudinal
studies
on
relapse.
Methods
Following
PRISMA
guidelines,
databases
including
PubMed,
Web
of
Science,
EBSCO,
Scopus
were
searched,
yielding
1992
articles.
Ultimately,
13
included
this
review.
Studies
evaluated
coded
using
a
tool
developed
by
researchers.
includes
that
explore
associations
related
alcohol
other
psychoactive
substances.
Results
Findings
inconsistent.
with
larger
sample
sizes
demonstrated
significant
Generally,
lack
clear
definition
relapse,
varied
assessment
methods,
differences
implementation
tasks
contributed
conflicting
results.
Conclusion
findings
provide
valuable
insights
for
professionals
field
researchers
focusing
bias.
Further
research
necessary
elucidate
emphasizing
need
definitions
reliable
methods
evaluate
both
In
addition,
investigating
impact
modification
outcomes
would
be
beneficial.
Addictive Behaviors Reports,
Journal Year:
2024,
Volume and Issue:
20, P. 100559 - 100559
Published: June 28, 2024
Drinking
motives
and
neurocognition
play
significant
roles
in
predicting
alcohol
use.
There
is
limited
research
examining
how
relief-driven
drinking
interact
with
use,
which
would
help
to
elucidate
the
neurocognitive-motivational
profiles
most
susceptible
harmful
drinking.
This
study
investigated
interactions
between
(response
inhibition
cognitive
flexibility)
drinking,
problem
Participants
completed
Alcohol
Use
Disorders
Identification
Test
–
Consumption
items
(AUDIT-C)
measure
behaviour,
online
tasks,
including
Value-Modulated
Attentional
Capture
Reversal
Task
(VMAC-R)
Stop
Signal
(SST).
The
sample
(N
=
368)
were
individuals
who
drink
alcohol,
included
a
subsample
52)
problematic
as
defined
by
self-identifying
having
primary
problem.
assessed
using
binary
coping
question
overall
sample,
Habit,
Reward,
Fear
Scale
(HRFS)
subsample.
Moderation
analyses
conducted
investigate
whether
flexibility
response
moderated
relationships
Cognitive
relationship
(overall
sample:
β
13.69,
p
0.017;
subsample:
1.45,
0.013).
Greater
associated
heavier
for
low
flexibility.
was
no
interaction
motives.
Relief-driven
inflexibility
drive
understanding
of
these
mechanisms
may
develop
more
targeted
effective
interventions
reducing
Journal of Behavioral Addictions,
Journal Year:
2024,
Volume and Issue:
13(3), P. 823 - 840
Published: Aug. 14, 2024
Abstract
Background
and
aims
Cognitive
control
reward-related
abnormalities
are
centrally
implicated
in
addiction.
However,
findings
from
longitudinal
studies
addressing
neurocognitive
predictors
of
addictive
behaviors
mixed.
Further,
little
work
has
been
conducted
predicting
non-substance-related
behaviors.
Our
study
aimed
to
assess
substance
non-substance
a
community
sample,
systematically
evaluating
each
function's
independent
influence
on
behavior.
Methods
Australians
(
N
=
294;
51.7%
female;
M[SD]
age
24.8[4.7]
years)
completed
online
tasks
surveys
at
baseline
3-month
follow-up.
Self-report
scales
assessed
problematic
alcohol
use,
eating
(AE),
pornography
use
(PPU),
internet
(PUI)
3-
6-month
follow-ups.
Linear
regressions
with
bootstrapping
for
behavior
across
period.
Results
Neurocognition
did
not
predict
AE
or
PUI
severity
Less
delay
discounting
predicted
higher
PPU
follow-up
β
−0.16,
p
0.005).
Poorer
performance
monitoring
0.004),
more
attentional
capture
3-months
0.14,
0.033).
−0.14,
0.003)
less
risk-taking
under
ambiguity
−0.11,
0.029)
All
were
small
effect
size.
None
the
variables
use.
Discussion
conclusions
We
unable
identify
core
set
specific
functions
that
reliably
multiple
types.
our
indicate
both
cognitive
different
ways.
Findings
suggest
there
may
be
partially
distinct
mechanisms
contributing
addiction
depending
The Canadian Journal of Psychiatry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 5, 2024
Impairments
in
impulse
control
and
related
neurocognitive
functioning
have
been
well
documented
both
substance
use
mental
disorder
populations.
While
high
impulsivity
other
executive
dysfunction
linked
to
negative
treatment
outcomes
these
populations,
no
study
date
has
examined
their
clinical
relevance
among
individuals
with
co-occurring
disorders
(or
concurrent
[CD]).
Objective
This
investigated
working
memory
CD
inpatients
across
compared
controls.
Methods
Patients
(
N
=
56,
M
age
38.2,
SD
11.7,
17F)
healthy
controls
50,
31.9,
10.0,
25F)
completed
a
battery
of
self-report
questionnaires
behavioural
tasks
assessing
(response
inhibition,
delay
discounting,
reflection,
decision-making).
were
assessed
within
2
weeks
admission
(baseline)
at
6
months
(follow-up).
Controls
single
session
baseline.
Patient
demographics,
diagnostic
status,
outcome
(discharge
or
without
medical
advice)
retrieved
from
records.
Results
Group
differences
demographics
probed
for
inclusion
as
covariates.
At
baseline,
patients
had
greater
self-reported
on
the
UPPS-P
(negative
positive
urgency)
BIS
(motor
non-planning),
discounting
than
Among
patients,
there
was
association
between
adherence
memory,
self-report,
impulsivity,
change
observed
baseline
follow-up.
Conclusions
is
first
assess
context
treatment.
exhibited
choice-based
various
measures.
The
absence
treatment-related
changes
suggests
that
conventional
treatments
may
be
neglecting
target
potentially
key
areas
functioning.
Further
research
needed
examine
how
affects
functions
CD,
impact
outcomes.
Addictive Behaviors,
Journal Year:
2023,
Volume and Issue:
150, P. 107904 - 107904
Published: Nov. 7, 2023
Neurocognitive
deficits
have
been
implicated
as
transdiagnostic
risk
markers
of
substance
use
disorders.
However,
these
yet
to
be
comprehensively
evaluated
in
other,
non-substance
addictions.
In
a
large,
general
community
sample
(N
=
475)
the
present
study
neurocognitive
correlates
problem
alcohol
and
three
non-substance-related
addictive
behaviors:
eating
(AE),
problematic
pornography
(PPU),
internet
(PUI),
identify
potential
shared
distinct
correlates.
A
Australian
residents
(54.4
%
female
M[SD]
age
32.4[11.9]
years)
completed
comprehensive
online
assessment
tasks
tapping
into
eight
expert-endorsed
domains
purportedly
associated
with
addiction.
Multiple
linear
regressions
bootstrapping
were
used
examine
associations
among
each
behavior
interest
neurocognition,
trait
impulsivity,
compulsivity,
well
key
covariates.
Neurocognition
was
differentially
behavior.
None
significantly
or
AE
(p
>.05),
poorer
performance
monitoring
higher
levels
PPU
PUI
(β
-0.10,
p
=.049;
β
-0.09,
=.028),
preference
for
delayed
gratification
more
severe
=.025).
Our
findings
theoretical
implications
how
we
understand
addiction
suggest
need
nuanced
approach
studying
behaviors
that
take
account
underlying
mechanisms
type
BMC Psychiatry,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Jan. 26, 2024
Abstract
Background
A
significant
number
of
individuals
with
alcohol
use
disorder
remain
unresponsive
to
currently
available
treatments,
which
calls
for
the
development
new
alternatives.
In
parallel,
psilocybin-assisted
therapy
has
recently
yielded
promising
preliminary
results.
Building
on
extant
findings,
proposed
study
is
set
evaluate
feasibility
and
clinical
efficacy
when
incorporated
as
an
auxiliary
intervention
during
inpatient
rehabilitation
severe
disorder.
Moreover,
it
intends
pinpoint
modifications
in
two
core
neurocognitive
systems
underscored
by
dual-process
models
addiction.
Methods
this
double-blind,
randomized,
placebo-controlled,
7-month
parallel-group
phase
II
superiority
trial,
62
participants
aged
21–64
years
will
be
enrolled
undergo
part
a
4-week
The
experimental
group
receive
high
dose
psilocybin
(30
mg),
whereas
control
active
placebo
(5
both
within
context
brief
standardized
psychotherapeutic
drawing
from
key
elements
acceptance
commitment
therapy.
primary
outcome
between-group
difference
regarding
change
percentage
heavy
drinking
days
baseline
four
weeks
posthospital
discharge,
while
safety
metrics
also
reported
outcomes.
Key
secondary
assessments
include
differences
terms
changes
(1)
behavior
parameters
up
six
months
(2)
symptoms
depression,
anxiety,
trauma,
global
functioning,
(3)
neuroplasticity
mechanisms
associated
addiction,
(4)
psychological
processes
alcohol-related
parameters.
Discussion
discussion
outlines
issues
that
might
arise
our
design.
Trial
registration
EudraCT
2022-002369-14
NCT06160232.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(17), P. 3718 - 3718
Published: Aug. 25, 2023
Eating
disorders
(EDs)
are
mental
health
diseases
characterized
by
dysfunctional
eating
patterns,
including
restrictive
eating,
avoidance
of
foods,
binge
and
compensative
behaviors
to
avoid
weight
increases
promote
thinness
(purging,
vomiting,
laxative/diuretics
misuse,
compulsive
exercise)
[...].