Enhanced attention-related alertness following right anterior insular cortex neurofeedback training DOI Creative Commons
Jeanette Popovova, Reza Mazloum, Gianluca Macauda

et al.

iScience, Journal Year: 2024, Volume and Issue: 27(2), P. 108915 - 108915

Published: Jan. 20, 2024

Highlights•The anterior insular cortex is critically involved in attentional functioning•Healthy participants increased activity their rAIC using rt-fMRI neurofeedback•rAIC upregulation enhanced alertness during attention task•Behavioral effects persisted up to three months after neurofeedback trainingSummaryThe cortex, a central node of the salience network, plays critical role cognitive control and attention. Here, we investigated feasibility enhancing real-time fMRI training that targets right (rAIC). 56 healthy adults underwent two sessions. The experimental group received feedback from neural responses rAIC, while groups sham primary visual or no feedback. Cognitive functioning was evaluated before, immediately after, post-training. Our results showed only successfully rAIC. Furthermore, this attention-related training. findings provide evidence for potential as viable approach alertness, which could pave way non-invasive therapeutic strategies address conditions characterized by deficits.Graphical abstract

Language: Английский

Real-time fMRI neurofeedback training to improve eating behavior by self-regulation of the dorsolateral prefrontal cortex: A randomized controlled trial in overweight and obese subjects DOI
Simon H. Kohl, Ralf Veit, Maartje S. Spetter

et al.

NeuroImage, Journal Year: 2019, Volume and Issue: 191, P. 596 - 609

Published: Feb. 22, 2019

Language: Английский

Citations

72
A systematic review of fMRI neurofeedback reporting and effects in clinical populations DOI Creative Commons
Anita Tursic, Judith Eck, Michael Lührs

et al.

NeuroImage Clinical, Journal Year: 2020, Volume and Issue: 28, P. 102496 - 102496

Published: Jan. 1, 2020

Real-time fMRI-based neurofeedback is a relatively young field with potential to impact the currently available treatments of various disorders. In order evaluate evidence clinical benefits and investigate how consistently studies report their methods results, an exhaustive search fMRI in populations was performed. Reporting evaluated using limited number Consensus on reporting experimental design cognitive-behavioral (CRED-NF checklist) items, which was, together statistical power sensitivity calculation, used also existing measures. The 62 found investigated regulation abilities and/or wide range disorders, but small sample sizes were therefore unable detect effects. Most points from CRED-NF checklist adequately reported by majority studies, some improvements are suggested for group comparisons relations between success benefits. To establish as tool, more emphasis should be placed future larger determined through priori calculations standardization procedures reporting.

Language: Английский

Citations

64
A randomized, controlled trial of alpha-rhythm EEG neurofeedback in posttraumatic stress disorder: A preliminary investigation showing evidence of decreased PTSD symptoms and restored default mode and salience network connectivity using fMRI DOI Creative Commons
Andrew A. Nicholson, Tomas Ros,

Maria Densmore

et al.

NeuroImage Clinical, Journal Year: 2020, Volume and Issue: 28, P. 102490 - 102490

Published: Jan. 1, 2020

The default-mode network (DMN) and salience (SN) have been shown to display altered connectivity in posttraumatic stress disorder (PTSD). Restoring aberrant within these networks with electroencephalogram neurofeedback (EEG-NFB) has previously be associated acute decreases symptoms. Here, we conducted a double-blind, sham-controlled randomized trial of alpha-rhythm EEG-NFB participants PTSD (n = 36) over 20-weeks. Our aim was provide mechanistic evidence underlying clinical improvements by examining changes via fMRI. Methods: We randomly assigned primary diagnosis either the experimental group 18) or sham-control 18). collected resting-state fMRI scans pre- post-NFB intervention, for both groups. further compared baseline brain measures pre-NFB age-matched healthy controls 36). Results: With regard outcome measure severity, found significant main effect time absence × interaction. Nevertheless, significantly decreased severity scores NFB only, when comparing (dz 0.71) 3-month follow-up 0.77) measures. Interestingly, suggest shift towards normalization DMN SN only. Both performance were correlated group. Critically, remission rates higher (61.1%) as (33.3%). Conclusion: current study shows therapeutic that are known psychopathology no patient dropouts. This preliminary investigation merits research demonstrate fully efficacy an adjunctive therapy PTSD.

Language: Английский

Citations

61
Network-based fMRI-neurofeedback training of sustained attention DOI Creative Commons
Gustavo Santo Pedro Pamplona,

Jennifer Heldner,

Robert Langner

et al.

NeuroImage, Journal Year: 2020, Volume and Issue: 221, P. 117194 - 117194

Published: July 22, 2020

The brain regions supporting sustained attention (sustained network; SAN) and mind-wandering (default-mode DMN) have been extensively studied. Nevertheless, this knowledge has not yet translated into advanced brain-based training protocols. Here, we used network-based real-time functional magnetic resonance imaging (fMRI) to provide healthy individuals with information about current activity levels in SAN DMN. Specifically, 15 participants trained control the difference between DMN hemodynamic completed behavioral tests before after neurofeedback training. Through training, improved controlling differential SAN-DMN feedback signal, which was accomplished mainly through deactivating After were able apply learned self-regulation of signal even when no longer available (i.e., during transfer runs). group although improvement temporally limited rarely exceeded mere practice effects that controlled by a test-retest group. outcomes suggest potential become non-invasive non-pharmacological tool enhance mitigate specific deficits.

Language: Английский

Citations

55
Effect of Neurofeedback Facilitation on Poststroke Gait and Balance Recovery DOI Creative Commons
Masahito Mihara,

Hiroaki Fujimoto,

Noriaki Hattori

et al.

Neurology, Journal Year: 2021, Volume and Issue: 96(21)

Published: April 21, 2021

To test the hypothesis that supplementary motor area (SMA) facilitation with functional near-infrared spectroscopy-mediated neurofeedback (fNIRS-NFB) augments poststroke gait and balance recovery, we conducted a 2-center, double-blind, randomized controlled trial involving 54 Japanese patients using 3-meter Timed Up Go (TUG) test.Patients subcortical stroke-induced mild to moderate disturbance more than 12 weeks from onset underwent 6 sessions of SMA during gait- balance-related imagery fNIRS-NFB. Participants were randomly allocated intervention (28 patients) or placebo (sham: 26 patients). In group, fNIRS signal contained participants' cortical activation information. The primary outcome was TUG improvement 4 postintervention.The group showed greater in (12.84 ± 15.07 seconds, 95% confidence interval 7.00-18.68) sham (5.51 7.64 2.43-8.60; difference 7.33 CI 0.83-13.83; p = 0.028), even after adjusting for covariates (group × time interaction; F1.23,61.69 4.50, 0.030, partial η2 0.083). Only significantly increased imagery-related enhancement resting-state connectivity between ventrolateral premotor area. Adverse effects associated fNIRS-mediated absent.SMA may augment recovery by modulating its related network.This study provides Class III evidence stroke, improves (UMIN000010723 at UMIN-CTR; umin.ac.jp/english/).

Language: Английский

Citations

50
Neurofeedback and the Aging Brain: A Systematic Review of Training Protocols for Dementia and Mild Cognitive Impairment DOI Creative Commons
Lucas R. Trambaiolli, Raymundo Cassani,

David M. A. Mehler

et al.

Frontiers in Aging Neuroscience, Journal Year: 2021, Volume and Issue: 13

Published: June 9, 2021

Dementia describes a set of symptoms that occur in neurodegenerative disorders and is characterized by gradual loss cognitive behavioral functions. Recently, non-invasive neurofeedback training has been explored as potential complementary treatment for patients suffering from dementia or mild impairment. Here we systematically reviewed studies protocols based on electroencephalography functional magnetic resonance imaging these groups patients. From total 1,912 screened studies, 10 were included our final sample ( N = 208 independent participants experimental 81 the control completing primary endpoint). We compared clinical efficacy across evaluated their designs reporting quality. In most showed improved scores different tests. However, data randomized controlled trials remains scarce, evidence standardized metrics still inconclusive. light recent meta-research developments field beyond, quality practices individual are reviewed. conclude with recommendations best future investigate effects

Language: Английский

Citations

45
Real-time fMRI neurofeedback as a new treatment for psychiatric disorders: A meta-analysis DOI Creative Commons

Pamela Pindi,

Josselin Houenou, Camille Piguet

et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2022, Volume and Issue: 119, P. 110605 - 110605

Published: July 16, 2022

Language: Английский

Citations

37
Real-time fMRI for brain-computer interfacing DOI
Bettina Sorger, Rainer Goebel

Handbook of clinical neurology, Journal Year: 2020, Volume and Issue: unknown, P. 289 - 302

Published: Jan. 1, 2020

Language: Английский

Citations

41
Real-Time Functional MRI in the Treatment of Mental Health Disorders DOI
Vincent Taschereau‐Dumouchel, Cody A. Cushing, Hakwan Lau

et al.

Annual Review of Clinical Psychology, Journal Year: 2022, Volume and Issue: 18(1), P. 125 - 154

Published: Jan. 21, 2022

Multiple mental disorders have been associated with dysregulation of precise brain processes. However, few therapeutic approaches can correct such specific patterns activity. Since the late 1960s and early 1970s, many researchers hoped that this feat could be achieved by closed-loop imaging approaches, as neurofeedback, aim to modulate activity directly. neurofeedback never gained mainstream acceptance in health, part due methodological considerations. In review, we argue that, when contemporary guidelines are followed, is one intervention methods psychology assessed double-blind placebo-controlled trials. Furthermore, using new advances machine learning statistics, it now possible target very for purposes. We review recent literature functional magnetic resonance discuss current future applications health.

Language: Английский

Citations

26
Closed-loop neuromodulation for studying spontaneous activity and causality DOI Creative Commons
Michal Ramot, Alex Martin

Trends in Cognitive Sciences, Journal Year: 2022, Volume and Issue: 26(4), P. 290 - 299

Published: Feb. 20, 2022

Language: Английский

Citations

25