Real-Time fMRI Functional Connectivity Neurofeedback Reducing Repetitive Negative Thinking in Depression: A Double-Blind, Randomized, Sham-Controlled Proof-of-Concept Trial

Psychotherapy and Psychosomatics, Journal Year: 2023, Volume and Issue: 92(2), P. 87 - 100

Published: Jan. 1, 2023

Introduction: Repetitive negative thinking (RNT) is a cognitive process focusing on self-relevant and experiences, leading to poor prognosis of major depressive disorder (MDD). We previously identified that connectivity between the precuneus/posterior cingulate cortex (PCC) right temporoparietal junction (rTPJ) was positively correlated with levels RNT. Objective: In this double-blind, randomized, sham-controlled, proof-of-concept trial, we employed real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) delineate neural processes may be causally linked RNT could potentially become treatment targets for MDD. Methods: MDD-affected individuals were assigned either active (n = 20) or sham feedback group 19). measured by Ruminative Response Scale-brooding subscale (RRS-B) before 1 week after intervention. Results: Individuals in but not showed significant reduction RRS-B; however, greater PCC-rTPJ unrelated RRS-B. Exploratory analyses revealed retrosplenial (RSC)-rTPJ yielded more pronounced RRS-B group. Conclusions: RtfMRI-nf effective reducing Considering underlying mechanism rtfMIR-nf, RSC rTPJ part network (i.e., default mode network) might collectively affect intensity Understanding relationship organization targeted changes clinical metrics, such as RNT, has potential guide development mechanism-based

Language: Английский

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A framework for application of consumer neuroscience in pro-environmental behavior change interventions

Frontiers in Human Neuroscience, Journal Year: 2022, Volume and Issue: 16

Published: Sept. 15, 2022

Most consumers are aware that climate change is a growing problem and admit action needed. However, research shows consumers’ behavior often does not conform to their value orientations. This value-behavior gap due contextual factors such as price, product design, social norms well individual personal hedonic values, environmental beliefs, the workload capacity an can handle. Because of this conflict interest, have hard time identifying true drivers behavior, they either unaware or unwilling acknowledge processes at play. Therefore, consumer neuroscience methods might provide valuable tool uncover implicit measurements pro-environmental (PEB). Several studies already defined neurophysiological differences between green non-green individuals; however, intervention must be developed motivate PEB among consumers. Motivating with reward punishment will most likely get users engaged in via brain structures related system, amygdala, nucleus accumbens, (pre)frontal cortex, where information subsequent affective responses encoded. The intensity experience increased when consciously considering achieve it. makes goal-directed potential aim interventions. article provides extensive review neuroscientific evidence for attitude, decision-making light sustainability incentives Based on review, we unite current theories future directions exploit power conditioning promoting engagement.

Language: Английский

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Down-regulation of theta amplitude through neurofeedback improves executive control network efficiency in healthy children

International Journal of Psychophysiology, Journal Year: 2024, Volume and Issue: unknown, P. 112301 - 112301

Published: Jan. 1, 2024

Language: Английский

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Mapping the evolution of neurofeedback research: a bibliometric analysis of trends and future directions

Frontiers in Human Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: May 10, 2024

Introduction This study conducts a bibliometric analysis on neurofeedback research to assess its current state and potential future developments. Methods It examined 3,626 journal articles from the Web of Science (WoS) using co-citation co-word methods. Results The identified three major clusters: “Real-Time fMRI Neurofeedback Self-Regulation Brain Activity,” “EEG Cognitive Performance Enhancement,” “Treatment ADHD Using Neurofeedback.” highlighted four key “Neurofeedback in Mental Health Research,” “Brain-Computer Interfaces for Stroke Rehabilitation,” Youth,” “Neural Mechanisms Emotion with Advanced Neuroimaging. Discussion in-depth significantly enhances our understanding dynamic field neurofeedback, indicating treating improving performance. offers non-invasive, ethical alternatives conventional psychopharmacology aligns trend toward personalized medicine, suggesting specialized solutions mental health rehabilitation as growing focus medical practice.

Language: Английский

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fNIRS neurofeedback facilitates emotion regulation: Exploring individual differences over the ventrolateral prefrontal cortex

NeuroImage, Journal Year: 2025, Volume and Issue: 308, P. 121079 - 121079

Published: Feb. 8, 2025

The ventrolateral prefrontal cortex (VLPFC) plays a pivotal role in emotion regulation, yet the effectiveness of neurofeedback (NF) training targeting VLPFC remains uncertain, suggesting significant individual differences outcomes. In this study, we aimed to clarify these by enrolling 90 participants, randomly assigned either an experimental group or sham (n = 48/42). Participants underwent VLPFC-NF over eight sessions across two consecutive days, while those received random signals from functional near-infrared spectroscopy (fNIRS). To investigate variability, participants were further categorized as high low-efficacy groups based on their efficiency, determined regression slope activity sessions. Our results revealed reduction negative emotions and increased during regulation high-efficacy group, compared both group. Importantly, benefit reflected decreased negativity ratings, was predicted NF efficiency. Furthermore, enhancement fully mediated relationship between efficiency benefits. with higher exhibited greater engagement leading superior emotional Additionally, linked habitual use reappraisal strategies daily life. This study provides novel causal evidence that can effectively enhance highlighting importance findings suggest offers promising personalized intervention strategy for improving potential applications treating disorders. research underscores approaches, offering new avenues tailored therapeutic interventions future.

Language: Английский

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Spinal and corticospinal excitability changes with voluntary modulation of motor cortex oscillations

NeuroImage, Journal Year: 2025, Volume and Issue: 311, P. 121156 - 121156

Published: April 7, 2025

The aim of this study was to investigate the effects EEG neurofeedback (NF)-induced modulation sensorimotor alpha (i.e., mu) rhythm on spinal and corticospinal tract (CST) excitability. Forty-three healthy volunteers participated in 3 sessions EEG-NF for upregulation (N=24) or downregulation (N=19) individual oscillations at central location Cz. Spinal excitability studied before during NF using H-reflex soleus muscle, CST tested after NF, through Motor-Evoked Potential (MEP) tibialis anterior muscle. Mu extracted current source density. Differences MEP during/after were analysed repeated measures analysis. relationship with motor cortexcortical estimated linear regression between change MEP/H-reflex, power mu upper portion rhythm, muh. changes significantly correlated muh (p-value < 0.044, |r|>0.42), while broad 0.04, |r|> 0.43). While no distinct effect versus found, correlations indicate an inverted U-shape cortical subcortical trends spinal/CST preserved when participants grouped by success task, outcome, indicating that net Cz weighs more than task attempted accomplish. consistent direction correlation both MEP, H-reflex, indicates modifications activity are associated adaptations lasting beyond session, evidencing neuroplasticity. Together found amplitude change, results provide support further research clinical implementation induce CNS plasticity, a prerequisite effective neural rehabilitation.

Language: Английский

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Enhancing creativity with covert neurofeedback: causal evidence for default-executive network coupling in creative thinking

Cerebral Cortex, Journal Year: 2025, Volume and Issue: 35(4)

Published: April 1, 2025

Abstract Creativity neuroscience has consistently reported increased functional connectivity between the default mode network and executive control supports creative cognition, potentially reflecting coordination of generative evaluative cognitive processes. However, evidence been purely correlational—no causal demonstrations show that network–executive interaction specifically drives performance. We sought for coupling in thinking using near-infrared spectroscopy–brain neurofeedback, which can endogenously modify through reinforcement learning. Importantly, we employed covert where participants were unaware specific brain activity being trained, allowing unbiased evaluation neural impacts. In a default-executive neurofeedback condition (n = 15), entrained medial prefrontal cortex dorsolateral cortex, hubs network, respectively. compared this with default-motor entraining supplementary motor area. Approximately 24 h later, led to during task (generating object uses), extending broader regions. Behaviorally, observed double dissociation: The default–executive idea originality, while improved go/no-go reaction times. thus provide first causally enhances

Language: Английский

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Whole-brain mechanism of neurofeedback therapy: predictive modeling of neurofeedback outcomes on repetitive negative thinking in depression

Translational Psychiatry, Journal Year: 2024, Volume and Issue: 14(1)

Published: Sept. 4, 2024

Language: Английский

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Successful modulation of temporoparietal junction activity and stimulus-driven attention by fNIRS-based neurofeedback—A randomized controlled proof-of-concept study

Imaging Neuroscience, Journal Year: 2023, Volume and Issue: 1, P. 1 - 26

Published: Aug. 18, 2023

Abstract The right temporoparietal junction (rTPJ) is a core hub in neural networks associated with reorienting of attention and social cognition. However, it remains unknown whether participants can learn to actively modulate their rTPJ activity via neurofeedback. Here, we explored the feasibility functional near-infrared spectroscopy (fNIRS)-based neurofeedback modulating its effect on functions such as visual perspective taking. In bidirectional regulation control group design, 50 healthy were reinforced either up- or downregulate activation over 4 days training. Both groups showed an increase from beginning training but only upregulation maintained this effect, while downregulation decline initial activation. This suggests learning exclusively, making challenging draw definitive conclusions about effectiveness observed group-specific effects behavioral level. We found significant x time interaction performance task changes, decreased reaction times (RTs) increased RTs across all conditions after Those low baseline greater improvements. perspective-taking task, however, that non-group-specific. These findings demonstrate fNIRS-based feasible method preliminary evidence neurophysiologically specific effects, thus paving way for future applications non-invasive modulation neuropsychiatric disorders.

Language: Английский

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Single Exercise for Core Symptoms and Executive Functions in ADHD: A Systematic Review and Meta-Analysis

Journal of Attention Disorders, Journal Year: 2023, Volume and Issue: 28(4), P. 399 - 414

Published: Dec. 29, 2023

Objectives: A systematic review and meta-analysis of studies single exercise on core symptoms executive function in adolescents with ADHD. Methods: Four databases were searched for the effects functioning Results: Thirteen included, a session had small effect-size improvements ADHD: 10 to 13 year olds early adolescent–elementary school years 18 24 late adolescent–college years. Moderate-intensity continuous training, high-intensity interval sessions less than 30 minutes, minutes more significantly improved cycling attention, inhibition, substance use, pre-study abstinence. Conclusions: an overall ameliorative effect

Language: Английский

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