Development and Arealization of the Cerebral Cortex

Neuron, Journal Year: 2019, Volume and Issue: 103(6), P. 980 - 1004

Published: Sept. 1, 2019

Language: Английский

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Sensorimotor processing in the rodent barrel cortex

Nature reviews. Neuroscience, Journal Year: 2019, Volume and Issue: 20(9), P. 533 - 546

Published: July 31, 2019

Language: Английский

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Circuit organization of the rodent medial prefrontal cortex

Trends in Neurosciences, Journal Year: 2021, Volume and Issue: 44(7), P. 550 - 563

Published: May 7, 2021

Language: Английский

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Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle

Nature reviews. Neuroscience, Journal Year: 2021, Volume and Issue: 22(7), P. 389 - 406

Published: May 6, 2021

Language: Английский

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Neuropixels Opto: Combining high-resolution electrophysiology and optogenetics

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

High-resolution extracellular electrophysiology is the gold standard for recording spikes from distributed neural populations, and especially powerful when combined with optogenetics manipulation of specific cell types high temporal resolution. We integrated these approaches into prototype Neuropixels Opto probes, which combine electronic photonic circuits. These devices pack 960 electrical sites two sets 14 light emitters onto a 1 cm shank, allowing spatially addressable optogenetic stimulation blue red light. In mouse cortex, probes delivered high-quality recordings together optogenetics, differentially activating or silencing neurons at distinct cortical depths. striatum other deep structures, efficient optotagging, facilitating identification in parallel. represent an unprecedented tool recording, identifying, manipulating neuronal populations.

Language: Английский

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Lateral inhibition in V1 controls neural and perceptual contrast sensitivity

Nature Neuroscience, Journal Year: 2025, Volume and Issue: unknown

Published: March 3, 2025

Language: Английский

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Simultaneous multiplane imaging with reverberation two-photon microscopy

Nature Methods, Journal Year: 2020, Volume and Issue: 17(3), P. 283 - 286

Published: Feb. 10, 2020

Language: Английский

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Prefrontal deep projection neurons enable cognitive flexibility via persistent feedback monitoring

Cell, Journal Year: 2021, Volume and Issue: 184(10), P. 2750 - 2766.e17

Published: April 16, 2021

Language: Английский

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The human motor cortex microcircuit: insights for neurodegenerative disease

Nature reviews. Neuroscience, Journal Year: 2020, Volume and Issue: 21(8), P. 401 - 415

Published: June 18, 2020

Language: Английский

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The Synaptic Organization of Layer 6 Circuits Reveals Inhibition as a Major Output of a Neocortical Sublamina

Cell Reports, Journal Year: 2019, Volume and Issue: 28(12), P. 3131 - 3143.e5

Published: Sept. 1, 2019

The canonical cortical microcircuit has principally been defined by interlaminar excitatory connections among the six layers of neocortex. However, neurons in layer 6 (L6), a whose functional organization is poorly understood, form relatively rare synaptic with other neurons. Here, we show that vast majority parvalbumin inhibitory sublamina within L6 send axons through toward pia. These receive local inputs from both major types and stronger input thalamocortical afferents than do neighboring pyramidal distribution these interneurons their connectivity further support subdivision standard cortex. Positioned to integrate long-distance this sublayer, generate an output. findings call for revision microcircuit.

Language: Английский

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