Mixing transcutaneous vagal nerve stimulation and galvanic cutaneous stimulation to decrease simulator adaptation syndrome DOI Creative Commons
Germán Galvéz-García, Patricio Mena‐Chamorro, Tomás Espinoza-Palavicino

et al.

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 2, 2024

Purpose Simulator Adaptation Syndrome arises from a perceptual discordance between expected and actual motion, giving rise to symptoms such as nausea disorientation. This research focused on determining the benefit of Transcutaneous Vagal Nerve Stimulation (tVNS) Galvanic Cutaneous (GCS), where both were applied in conjunction, compared their administration isolation, decrease (SAS). Method A driving simulation study was proposed SAS, body balance, performance measured. These measurements taken during seven different stimulation scenarios with baseline condition without against tVNS GCS conditions. Results The main result showed that combination reduced SAS improved balance more successfully than isolation. Conclusion Similar neuromodulation temporoparietal junction is mitigate for (although additional explanations are discussed). Applying techniques simultaneously encouraged future interventions.

Language: Английский

The impact of transcutaneous vagus nerve stimulation on anterior cingulate cortex activity in a cognitive control task DOI Creative Commons
Özde Sönmez, Elfriede R Holstein, Sebastian Puschmann

et al.

Psychophysiology, Journal Year: 2025, Volume and Issue: 62(1)

Published: Jan. 1, 2025

Abstract Transcutaneous vagus nerve stimulation (tVNS) offers a non‐invasive method to enhance noradrenergic neurotransmission in the human brain, thereby increasing cognitive control. Here, we investigate if changes control induced by tVNS are mediated through locus coeruleus‐induced modifications of neural activity anterior cingulate cortex. Young healthy participants engaged simple task focusing on response inhibition and more complex that involved both working memory, inside magnetic resonance imaging scanner. The tasks were executed using randomized within‐subject design, with undergoing auricular sham separate sessions. significantly changed performance reflected greater propensity respond. Furthermore, observed significant increase cortex during under tVNS. Functional connectivity analyses revealed positive coupling between coeruleus cortex, however, this was not modulated findings suggest can modulate While these effects an impact key region conflict monitoring control, behavioral indicative shift bias rather than enhanced

Language: Английский

Citations

2

Transcutaneous Auricular Vagus Nerve Stimulation Enhances Emotional Processing and Long‐Term Recognition Memory: Electrophysiological Evidence Across Two Studies DOI Creative Commons
Carlos Ventura‐Bort, Manon Giraudier, Mathias Weymar

et al.

Psychophysiology, Journal Year: 2025, Volume and Issue: 62(3)

Published: March 1, 2025

ABSTRACT Recently, we found that continuous transcutaneous auricular vagus nerve stimulation (taVNS) facilitates the encoding and later recollection of emotionally relevant information, as indicated by differences in late positive potential (LPP), memory performance, ERP Old/New effect. Here, aimed to conceptually replicate extend these findings investigating effects different time‐dependent taVNS protocols. In Study 1, an identical paradigm our previous study was employed with interval (30‐s on/off). Participants viewed unpleasant neutral scenes on two consecutive days while receiving or sham completed a recognition test 1 week later. Replicating results, images encoded under taVNS, compared stimulation, elicited larger amplitudes earlier window LPP during encoding, well more pronounced differences. However, no performance were found. 2, followed up synchronizing cycle image presentation determine for off cycles. We could enhancing brain potentials (early differences) improved recollection‐based both images, independently cycle. Overall, results suggest increases electrophysiological correlates emotional retrieval time‐independent manner, substantiating nerve's role processing formation, opening new venues improving mnemonic processes clinical non‐clinical populations.

Language: Английский

Citations

1

Effects of Transcutaneous Auricular Vagus Nerve Stimulation on the P300: Do Stimulation Duration and Stimulation Type Matter? DOI Creative Commons
Manon Giraudier, Carlos Ventura‐Bort, Mathias Weymar

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 690 - 690

Published: July 10, 2024

Non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) has attracted increasing interest as a neurostimulation tool with potential applications in modulating cognitive processes such attention and memory, possibly through the modulation of locus–coeruleus noradrenaline system. Studies examining P300 brain-related component correlate noradrenergic activity, however, have yielded inconsistent findings, due to differences parameters, thus necessitating further investigation. In this event-related study involving 61 participants, therefore, we examined how changes taVNS specifically type (interval vs. continuous stimulation) duration, influence amplitudes during visual novelty oddball task. Although no effects were found over whole cluster time window P300, cluster-based permutation tests revealed distinct impact on response for small electrode cluster, characterized by larger observed easy targets (i.e., stimuli that are easily discernible from standards) following compared sham stimulation. Notably, our findings suggested significantly modulated showing (taVNS sham) hard standards interval We interaction duration target-related P300. While align previous research, investigation is warranted fully elucidate its utility reliable marker neuromodulation field.

Language: Английский

Citations

4

Vagus Nerve Stimulation for Improvement of Vascular Cognitive Impairment DOI Creative Commons

E Ridengnaxi,

Yan Wang

Neuropsychiatric Disease and Treatment, Journal Year: 2024, Volume and Issue: Volume 20, P. 1445 - 1451

Published: July 1, 2024

Vagus nerve stimulation (VNS) is acknowledged as a highly effective therapy for various neurological conditions, including refractory epilepsy, depression, Alzheimer's disease (AD), migraine, and stroke. Presently, there an increasing focus on understanding the impact of VNS cognitive aspects. Numerous studies suggest that suppresses body's inflammatory response, leading to enhanced function in patients. Vascular impairment (VCI) severe dysfunction syndrome resulting from prolonged chronic cerebral hypoperfusion (CCH), where primary pathogenesis CCH-induced neuroinflammation. In this paper, we present comprehensive overview research advancements using treating VCI discuss improves patients by suppressing neuroinflammation, offering insights into potential novel approach addressing condition.

Language: Английский

Citations

3

Dual-task improvement of older adults after treadmill walking combined with blood flow restriction of low occlusion pressure: the effect on the heart–brain axis DOI Creative Commons
Yi-Ching Chen,

I-Ping Lo,

Yi-Ying Tsai

et al.

Journal of NeuroEngineering and Rehabilitation, Journal Year: 2024, Volume and Issue: 21(1)

Published: July 12, 2024

Abstract Objective This study explored the impact of one session low-pressure leg blood flow restriction (BFR) during treadmill walking on dual-task performance in older adults using neurovisceral integration model framework. Methods Twenty-seven participated 20-min sessions, either with BFR (100 mmHg cuff pressure both thighs) or without it (NBFR). Dual-task performance, measured through light-pod tapping while standing foam, and heart rate variability were compared. Results Following walking, reaction time ( p = 0.002) sway area 0.012) posture significantly reduced. Participants exhibited a lower mean < 0.001) higher 0.038) walking. Notably, also led to band-specific reductions regional brain activities (theta, alpha, beta bands, 0.05). The topology EEG network theta alpha bands became more star-like post-test after 0.005). Conclusion improves via vagally-mediated superior neural economy. approach has potential prevent age-related falls by promoting cognitive reserves.

Language: Английский

Citations

2

Can transcutaneous auricular vagus nerve stimulation mitigate vigilance loss? Examining the effects of stimulation at individualized versus constant current intensity DOI Creative Commons
Fernando Gabriel Luna, Juan Lupiáñez, Stefanie König

et al.

Psychophysiology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 21, 2024

Abstract According to the arousal model of vigilance, locus coeruleus‐norepinephrine (LC‐NE) system modulates sustained attention over long periods by regulating physiological arousal. Recent research has proposed that transcutaneous auricular vagus nerve stimulation (taVNS) indirect markers LC‐NE activity, although its effects on vigilance have not yet been examined. Aiming develop a safe and noninvasive procedure prevent failures in prolonged tasks, present study examined whether taVNS can mitigate loss while modulating activity. Following preregistered protocol ( https://osf.io/tu2xy/ ), 50 participants completed three repeated sessions randomized order, which either active at individualized intensity set participant, 0.5 mA for all participants, or sham taVNS, was delivered performing an attentional task (i.e., ANTI‐Vea). Changes salivary alpha‐amylase cortisol concentrations were measured as Self‐reports feelings associated with guessing rate active/sham conditions supported efficacy single‐blind procedure. Contrary our predictions, observed decrement modulated taVNS. Pairwise comparisons showed mitigation reduction across time. Interestingly, Spearman's correlational analyses some interindividual LC‐NE, evidenced positive associations between changes but We highlight relevance replicating extending outcomes, investigating further parameters other

Language: Английский

Citations

2

Effects of transcutaneous auricular vagus nerve stimulation and exploration of brain network mechanisms in children with high−functioning autism spectrum disorder: study protocol for a randomized controlled trial DOI Creative Commons
Ke Sun, Ying Li,

Zhenhang Zhai

et al.

Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15

Published: Feb. 5, 2024

Background Autism Spectrum Disorders (ASD) are a collection of neurodevelopmental diseases characterized by poor social interaction and communication, limited range interests, stereotyped behavior. High-functioning autism (HFA) indicates subgroup individuals with who possess cognitive and/or language skills that within the average to above-normal for their age. Transcutaneous auricular vagus nerve stimulation (taVNS) holds promise in children HFA. However, few studies have used randomized controlled trials validate effectiveness taVNS. Therefore, this study, we intend provide study protocol examine therapeutic effects taVNS diagnosed HFA investigate process brain network remodeling ASD using functional imaging techniques observe alterations large-scale neural networks. Methods design We planned employ randomized, double-blind experimental design, including 40 receiving sham real stimulation. will assess clinical scales perform examinations before after Additionally, include age- gender-matched healthy as controls conduct examinations. plan first Furthermore, impact on network. Discussion was low-risk, easy-to-administer, low-cost, portable option modulate system. may improve performance Changes properties be related efficacy Clinical trial registration http://www.chictr.org.cn , identifier ChiCTR2300074035.

Language: Английский

Citations

1

Cognitive Functions following Trigeminal Neuromodulation DOI Creative Commons
Beniamina Mercante, Paolo Enrico, Franca Deriu

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 11(9), P. 2392 - 2392

Published: Aug. 27, 2023

Vast scientific effort in recent years have been focused on the search for effective and safe treatments cognitive decline. In this regard, non-invasive neuromodulation has gained increasing attention its reported effectiveness promoting recovery of multiple domains after central nervous system damage. short review, we discuss available evidence supporting a possible effect trigeminal nerve stimulation (TNS). particular, ask that, while TNS widely successfully used treatment various neuropsychiatric conditions, as far research field is concerned, where does stand? The largest cranial nerve, conveying sensory information from face to nuclei, there thalamus up somatosensory cortex. On these bases, bottom-up mechanism proposed, positing that TNS-induced modulation brainstem noradrenergic may affect function brain networks involved cognition. Nevertheless, despite promising theories, date, use empowering and/or decline several challenges ahead it, mainly due little uniformity protocols. However, continues grow, standardization practice will allow data comparisons across studies, leading optimized protocols targeting specific circuitries, which may, turn, influence cognition designed manner.

Language: Английский

Citations

3

Effectiveness of Vagal Nerve Stimulation on Obsessive Compulsive Disorder Among Post Covid-19 Infected Individuals DOI Creative Commons

Padma Priya.R,

Vignesh Srinivasan, Prathap Suganthirababu

et al.

Indian Journal of Physiotherapy and Occupational Therapy - An International Journal, Journal Year: 2024, Volume and Issue: 18, P. 120 - 125

Published: Jan. 21, 2024

Background: COVID-19 has impacted everyday life and many people are affected by it. Regular Hand washing,maintaining hygiene, avoiding handshaking & face-to-face interaction, social distancing, quarantine areprecautionary measures which result in rapidly increasing depression anxiety among common populationand it results OCD.Purpose: This study aims to investigate the effectiveness of vagal nerve stimulation on obsessive compulsivedisorder post-covid 19 infected individuals.Methodology: A total 20 participants was selected using Purposive sampling technique based theinclusion exclusion criteria. Then, were allocated into 2 groups closed envelope methodand control group receive cognitive behavioural therapy for 30 minutes, 4 sessions/weekfor weeks. The experimental Transcutaneous auricular stimulation. stimulationwas given minutes,4sessions/week along with CBT.Result: With a p value 0.001, transcutaneous activation significantly reduced obsessivecompulsive disorder symptoms after 4weeks group.Conclusion: Study showed that effective reducingsymptoms OCD post covid-19 individuals.

Language: Английский

Citations

0

Can transcutaneous auricular vagus nerve stimulation mitigate vigilance loss? Examining the effects of stimulation at individualized vs. constant current intensity DOI Open Access
Fernando Gabriel Luna, Juan Lupiáñez, Stefanie König

et al.

Authorea (Authorea), Journal Year: 2024, Volume and Issue: unknown

Published: May 27, 2024

According to the arousal model of vigilance, locus coeruleus-norepinephrine (LC-NE) system modulates sustained attention over long periods by regulating physiological arousal. Recent research has proposed that transcutaneous auricular vagus nerve stimulation (taVNS) indirect markers LC-NE activity, although its effects on vigilance have not yet been examined. Aiming develop a safe and non-invasive procedure prevent failures in prolonged tasks, present study examined possibility mitigate loss stimulating via taVNS. Following pre-registered protocol (https://osf.io/tu2xy/), 50 participants completed three repeated-sessions randomized order which either active taVNS at individualized intensity set participant, 0.5 mA for all participants, or sham taVNS, was delivered while performing an attentional task (i.e., ANTI-Vea). Changes salivary alpha-amylase cortisol concentrations were measured as activity. Self-reports feelings associated with guessing rate active/sham conditions supported efficacy single-blind procedure. Contrary our predictions, observed decrement modulated Pairwise comparisons showed mitigation reduction across time. Interestingly, Spearman’s correlational analyses some inter-individual LC-NE, evidenced positive associations between changes but We highlight relevance replicating extending outcomes, investigating further parameters other

Language: Английский

Citations

0