Frontiers in Psychology,
Journal Year:
2024,
Volume and Issue:
15
Published: Oct. 2, 2024
Purpose
Simulator
Adaptation
Syndrome
arises
from
a
perceptual
discordance
between
expected
and
actual
motion,
giving
rise
to
symptoms
such
as
nausea
disorientation.
This
research
focused
on
determining
the
benefit
of
Transcutaneous
Vagal
Nerve
Stimulation
(tVNS)
Galvanic
Cutaneous
(GCS),
where
both
were
applied
in
conjunction,
compared
their
administration
isolation,
decrease
(SAS).
Method
A
driving
simulation
study
was
proposed
SAS,
body
balance,
performance
measured.
These
measurements
taken
during
seven
different
stimulation
scenarios
with
baseline
condition
without
against
tVNS
GCS
conditions.
Results
The
main
result
showed
that
combination
reduced
SAS
improved
balance
more
successfully
than
isolation.
Conclusion
Similar
neuromodulation
temporoparietal
junction
is
mitigate
for
(although
additional
explanations
are
discussed).
Applying
techniques
simultaneously
encouraged
future
interventions.
Psychophysiology,
Journal Year:
2025,
Volume and Issue:
62(1)
Published: Jan. 1, 2025
Abstract
Transcutaneous
vagus
nerve
stimulation
(tVNS)
offers
a
non‐invasive
method
to
enhance
noradrenergic
neurotransmission
in
the
human
brain,
thereby
increasing
cognitive
control.
Here,
we
investigate
if
changes
control
induced
by
tVNS
are
mediated
through
locus
coeruleus‐induced
modifications
of
neural
activity
anterior
cingulate
cortex.
Young
healthy
participants
engaged
simple
task
focusing
on
response
inhibition
and
more
complex
that
involved
both
working
memory,
inside
magnetic
resonance
imaging
scanner.
The
tasks
were
executed
using
randomized
within‐subject
design,
with
undergoing
auricular
sham
separate
sessions.
significantly
changed
performance
reflected
greater
propensity
respond.
Furthermore,
observed
significant
increase
cortex
during
under
tVNS.
Functional
connectivity
analyses
revealed
positive
coupling
between
coeruleus
cortex,
however,
this
was
not
modulated
findings
suggest
can
modulate
While
these
effects
an
impact
key
region
conflict
monitoring
control,
behavioral
indicative
shift
bias
rather
than
enhanced
Psychophysiology,
Journal Year:
2025,
Volume and Issue:
62(3)
Published: March 1, 2025
ABSTRACT
Recently,
we
found
that
continuous
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS)
facilitates
the
encoding
and
later
recollection
of
emotionally
relevant
information,
as
indicated
by
differences
in
late
positive
potential
(LPP),
memory
performance,
ERP
Old/New
effect.
Here,
aimed
to
conceptually
replicate
extend
these
findings
investigating
effects
different
time‐dependent
taVNS
protocols.
In
Study
1,
an
identical
paradigm
our
previous
study
was
employed
with
interval
(30‐s
on/off).
Participants
viewed
unpleasant
neutral
scenes
on
two
consecutive
days
while
receiving
or
sham
completed
a
recognition
test
1
week
later.
Replicating
results,
images
encoded
under
taVNS,
compared
stimulation,
elicited
larger
amplitudes
earlier
window
LPP
during
encoding,
well
more
pronounced
differences.
However,
no
performance
were
found.
2,
followed
up
synchronizing
cycle
image
presentation
determine
for
off
cycles.
We
could
enhancing
brain
potentials
(early
differences)
improved
recollection‐based
both
images,
independently
cycle.
Overall,
results
suggest
increases
electrophysiological
correlates
emotional
retrieval
time‐independent
manner,
substantiating
nerve's
role
processing
formation,
opening
new
venues
improving
mnemonic
processes
clinical
non‐clinical
populations.
Brain Sciences,
Journal Year:
2024,
Volume and Issue:
14(7), P. 690 - 690
Published: July 10, 2024
Non-invasive
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS)
has
attracted
increasing
interest
as
a
neurostimulation
tool
with
potential
applications
in
modulating
cognitive
processes
such
attention
and
memory,
possibly
through
the
modulation
of
locus–coeruleus
noradrenaline
system.
Studies
examining
P300
brain-related
component
correlate
noradrenergic
activity,
however,
have
yielded
inconsistent
findings,
due
to
differences
parameters,
thus
necessitating
further
investigation.
In
this
event-related
study
involving
61
participants,
therefore,
we
examined
how
changes
taVNS
specifically
type
(interval
vs.
continuous
stimulation)
duration,
influence
amplitudes
during
visual
novelty
oddball
task.
Although
no
effects
were
found
over
whole
cluster
time
window
P300,
cluster-based
permutation
tests
revealed
distinct
impact
on
response
for
small
electrode
cluster,
characterized
by
larger
observed
easy
targets
(i.e.,
stimuli
that
are
easily
discernible
from
standards)
following
compared
sham
stimulation.
Notably,
our
findings
suggested
significantly
modulated
showing
(taVNS
sham)
hard
standards
interval
We
interaction
duration
target-related
P300.
While
align
previous
research,
investigation
is
warranted
fully
elucidate
its
utility
reliable
marker
neuromodulation
field.
Neuropsychiatric Disease and Treatment,
Journal Year:
2024,
Volume and Issue:
Volume 20, P. 1445 - 1451
Published: July 1, 2024
Vagus
nerve
stimulation
(VNS)
is
acknowledged
as
a
highly
effective
therapy
for
various
neurological
conditions,
including
refractory
epilepsy,
depression,
Alzheimer's
disease
(AD),
migraine,
and
stroke.
Presently,
there
an
increasing
focus
on
understanding
the
impact
of
VNS
cognitive
aspects.
Numerous
studies
suggest
that
suppresses
body's
inflammatory
response,
leading
to
enhanced
function
in
patients.
Vascular
impairment
(VCI)
severe
dysfunction
syndrome
resulting
from
prolonged
chronic
cerebral
hypoperfusion
(CCH),
where
primary
pathogenesis
CCH-induced
neuroinflammation.
In
this
paper,
we
present
comprehensive
overview
research
advancements
using
treating
VCI
discuss
improves
patients
by
suppressing
neuroinflammation,
offering
insights
into
potential
novel
approach
addressing
condition.
Journal of NeuroEngineering and Rehabilitation,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: July 12, 2024
Abstract
Objective
This
study
explored
the
impact
of
one
session
low-pressure
leg
blood
flow
restriction
(BFR)
during
treadmill
walking
on
dual-task
performance
in
older
adults
using
neurovisceral
integration
model
framework.
Methods
Twenty-seven
participated
20-min
sessions,
either
with
BFR
(100
mmHg
cuff
pressure
both
thighs)
or
without
it
(NBFR).
Dual-task
performance,
measured
through
light-pod
tapping
while
standing
foam,
and
heart
rate
variability
were
compared.
Results
Following
walking,
reaction
time
(
p
=
0.002)
sway
area
0.012)
posture
significantly
reduced.
Participants
exhibited
a
lower
mean
<
0.001)
higher
0.038)
walking.
Notably,
also
led
to
band-specific
reductions
regional
brain
activities
(theta,
alpha,
beta
bands,
0.05).
The
topology
EEG
network
theta
alpha
bands
became
more
star-like
post-test
after
0.005).
Conclusion
improves
via
vagally-mediated
superior
neural
economy.
approach
has
potential
prevent
age-related
falls
by
promoting
cognitive
reserves.
Psychophysiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 21, 2024
Abstract
According
to
the
arousal
model
of
vigilance,
locus
coeruleus‐norepinephrine
(LC‐NE)
system
modulates
sustained
attention
over
long
periods
by
regulating
physiological
arousal.
Recent
research
has
proposed
that
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS)
indirect
markers
LC‐NE
activity,
although
its
effects
on
vigilance
have
not
yet
been
examined.
Aiming
develop
a
safe
and
noninvasive
procedure
prevent
failures
in
prolonged
tasks,
present
study
examined
whether
taVNS
can
mitigate
loss
while
modulating
activity.
Following
preregistered
protocol
(
https://osf.io/tu2xy/
),
50
participants
completed
three
repeated
sessions
randomized
order,
which
either
active
at
individualized
intensity
set
participant,
0.5
mA
for
all
participants,
or
sham
taVNS,
was
delivered
performing
an
attentional
task
(i.e.,
ANTI‐Vea).
Changes
salivary
alpha‐amylase
cortisol
concentrations
were
measured
as
Self‐reports
feelings
associated
with
guessing
rate
active/sham
conditions
supported
efficacy
single‐blind
procedure.
Contrary
our
predictions,
observed
decrement
modulated
taVNS.
Pairwise
comparisons
showed
mitigation
reduction
across
time.
Interestingly,
Spearman's
correlational
analyses
some
interindividual
LC‐NE,
evidenced
positive
associations
between
changes
but
We
highlight
relevance
replicating
extending
outcomes,
investigating
further
parameters
other
Frontiers in Psychiatry,
Journal Year:
2024,
Volume and Issue:
15
Published: Feb. 5, 2024
Background
Autism
Spectrum
Disorders
(ASD)
are
a
collection
of
neurodevelopmental
diseases
characterized
by
poor
social
interaction
and
communication,
limited
range
interests,
stereotyped
behavior.
High-functioning
autism
(HFA)
indicates
subgroup
individuals
with
who
possess
cognitive
and/or
language
skills
that
within
the
average
to
above-normal
for
their
age.
Transcutaneous
auricular
vagus
nerve
stimulation
(taVNS)
holds
promise
in
children
HFA.
However,
few
studies
have
used
randomized
controlled
trials
validate
effectiveness
taVNS.
Therefore,
this
study,
we
intend
provide
study
protocol
examine
therapeutic
effects
taVNS
diagnosed
HFA
investigate
process
brain
network
remodeling
ASD
using
functional
imaging
techniques
observe
alterations
large-scale
neural
networks.
Methods
design
We
planned
employ
randomized,
double-blind
experimental
design,
including
40
receiving
sham
real
stimulation.
will
assess
clinical
scales
perform
examinations
before
after
Additionally,
include
age-
gender-matched
healthy
as
controls
conduct
examinations.
plan
first
Furthermore,
impact
on
network.
Discussion
was
low-risk,
easy-to-administer,
low-cost,
portable
option
modulate
system.
may
improve
performance
Changes
properties
be
related
efficacy
Clinical
trial
registration
http://www.chictr.org.cn
,
identifier
ChiCTR2300074035.
Biomedicines,
Journal Year:
2023,
Volume and Issue:
11(9), P. 2392 - 2392
Published: Aug. 27, 2023
Vast
scientific
effort
in
recent
years
have
been
focused
on
the
search
for
effective
and
safe
treatments
cognitive
decline.
In
this
regard,
non-invasive
neuromodulation
has
gained
increasing
attention
its
reported
effectiveness
promoting
recovery
of
multiple
domains
after
central
nervous
system
damage.
short
review,
we
discuss
available
evidence
supporting
a
possible
effect
trigeminal
nerve
stimulation
(TNS).
particular,
ask
that,
while
TNS
widely
successfully
used
treatment
various
neuropsychiatric
conditions,
as
far
research
field
is
concerned,
where
does
stand?
The
largest
cranial
nerve,
conveying
sensory
information
from
face
to
nuclei,
there
thalamus
up
somatosensory
cortex.
On
these
bases,
bottom-up
mechanism
proposed,
positing
that
TNS-induced
modulation
brainstem
noradrenergic
may
affect
function
brain
networks
involved
cognition.
Nevertheless,
despite
promising
theories,
date,
use
empowering
and/or
decline
several
challenges
ahead
it,
mainly
due
little
uniformity
protocols.
However,
continues
grow,
standardization
practice
will
allow
data
comparisons
across
studies,
leading
optimized
protocols
targeting
specific
circuitries,
which
may,
turn,
influence
cognition
designed
manner.
Indian Journal of Physiotherapy and Occupational Therapy - An International Journal,
Journal Year:
2024,
Volume and Issue:
18, P. 120 - 125
Published: Jan. 21, 2024
Background:
COVID-19
has
impacted
everyday
life
and
many
people
are
affected
by
it.
Regular
Hand
washing,maintaining
hygiene,
avoiding
handshaking
&
face-to-face
interaction,
social
distancing,
quarantine
areprecautionary
measures
which
result
in
rapidly
increasing
depression
anxiety
among
common
populationand
it
results
OCD.Purpose:
This
study
aims
to
investigate
the
effectiveness
of
vagal
nerve
stimulation
on
obsessive
compulsivedisorder
post-covid
19
infected
individuals.Methodology:
A
total
20
participants
was
selected
using
Purposive
sampling
technique
based
theinclusion
exclusion
criteria.
Then,
were
allocated
into
2
groups
closed
envelope
methodand
control
group
receive
cognitive
behavioural
therapy
for
30
minutes,
4
sessions/weekfor
weeks.
The
experimental
Transcutaneous
auricular
stimulation.
stimulationwas
given
minutes,4sessions/week
along
with
CBT.Result:
With
a
p
value
0.001,
transcutaneous
activation
significantly
reduced
obsessivecompulsive
disorder
symptoms
after
4weeks
group.Conclusion:
Study
showed
that
effective
reducingsymptoms
OCD
post
covid-19
individuals.
Authorea (Authorea),
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 27, 2024
According
to
the
arousal
model
of
vigilance,
locus
coeruleus-norepinephrine
(LC-NE)
system
modulates
sustained
attention
over
long
periods
by
regulating
physiological
arousal.
Recent
research
has
proposed
that
transcutaneous
auricular
vagus
nerve
stimulation
(taVNS)
indirect
markers
LC-NE
activity,
although
its
effects
on
vigilance
have
not
yet
been
examined.
Aiming
develop
a
safe
and
non-invasive
procedure
prevent
failures
in
prolonged
tasks,
present
study
examined
possibility
mitigate
loss
stimulating
via
taVNS.
Following
pre-registered
protocol
(https://osf.io/tu2xy/),
50
participants
completed
three
repeated-sessions
randomized
order
which
either
active
taVNS
at
individualized
intensity
set
participant,
0.5
mA
for
all
participants,
or
sham
taVNS,
was
delivered
while
performing
an
attentional
task
(i.e.,
ANTI-Vea).
Changes
salivary
alpha-amylase
cortisol
concentrations
were
measured
as
activity.
Self-reports
feelings
associated
with
guessing
rate
active/sham
conditions
supported
efficacy
single-blind
procedure.
Contrary
our
predictions,
observed
decrement
modulated
Pairwise
comparisons
showed
mitigation
reduction
across
time.
Interestingly,
Spearman’s
correlational
analyses
some
inter-individual
LC-NE,
evidenced
positive
associations
between
changes
but
We
highlight
relevance
replicating
extending
outcomes,
investigating
further
parameters
other