Environment International, Journal Year: 2024, Volume and Issue: 183, P. 108417 - 108417
Published: Jan. 1, 2024
The association of specific PM2.5 chemical constituents with childhood overweight or obesity (OWOB) remain unclear. Furthermore, the long-term impacts exposure on trajectory children's body mass index (BMI) have not been explored. We conducted a longitudinal study among 1,450,830 Chinese children aged 6-19 years from Beijing and Zhongshan in China during 2005-2018 to examine associations its incident OWOB risk. extracted five main component Tracking Air Pollution (TAP) dataset. Cox proportional hazards models were applied quantify exposure-response associations. further performed principal analysis (PCA) handle multi-collinearity used quantile g-computation (QGC) approach analyze mixtures. Additionally, we selected 125,863 at least 8 physical examination measurements combined group-based (GBTM) multinomial logistic regression explore BMI Z-score trajectories years. observed each interquartile range increment was significantly associated 5.1% increase risk (95% confidence Interval [CI]: 1.036-1.066). also found black carbon, sulfate, organic matter, often linked fossil combustion, had comparable larger estimates effect (HR = 1.139-1.153) than PM2.5. Exposure mass, nitrate, ammonium, matter carbon an increased odds being assigned persistent trajectory. Our findings provide evidence that mainly fuel combustion may perceptible influence China. Moreover, contributes lager trajectories.
Language: Английский
Citations
12L-Arginine and Nitric Oxide in Vascular Regulation—Experimental Findings in the Context of Blood Donation
Nutrients, Journal Year: 2025, Volume and Issue: 17(4), P. 665 - 665
Published: Feb. 13, 2025
This narrative review provides an analysis of the role nitric oxide (NO) and its precursors, particularly L-arginine, in vascular regulation health, with emphasis on findings from our experimental research animal models. NO serves as a critical mediator function, contributing to vasodilation, blood flow, prevention thrombosis. As primary precursor NO, L-arginine is essential for maintaining endothelial integrity, modulating mitochondrial reducing oxidative damage. synthesises data contextualises these within physiological challenges faced by donors, such repeated donation associated stress. It examines effects supplementation respiration, lipid peroxidation, microsomal oxidation different conditions, including differences age, gender, dietary interventions. The mechanisms which enhances production, improves elasticity, alleviates dysfunction caused reduced bioavailability are also investigated. By integrating insights existing literature, this perspective potential address specific needs donors. highlights importance personalised nutritional approaches enhancing donor recovery resilience. In addition, assesses wider implications mitigating stress preserving function. interplay between bioavailability, factors, adaptation donors highlighted, along identification current knowledge gaps recommendations future research. presenting both original evidence synthesis article therapeutic promoting health context donation.
Language: Английский
Citations
1Stimuli‐Responsive NO Delivery Platforms for Bacterial Infection Treatment
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(31)
Published: Aug. 22, 2024
The prevalence of drug-resistant bacterial infections has emerged as a grave threat to clinical treatment and global human health, presenting one the foremost challenges in medical care. Thus, there is an urgent imperative develop safe efficacious novel antimicrobial strategies. Nitric oxide (NO) recognized endogenous signaling molecule, which plays pivotal role numerous pathological processes. Currently, NO garnered significant interest antibacterial agent due its capability eradicate bacteria, disrupt biofilms, facilitate wound healing, all while circumventing emergence drug resistance. However, inherently unstable characteristic therapeutic gas renders controlled administration gases exceedingly challenging. Hence, this review, current challenge infection discussed; then it briefly elucidated mechanism comprehensively delineate recent advancements stimulus-responsive delivery platforms, along with their merits, obstacles, prospective avenues for application. This review offers guidance future NO-medicated anti-infection therapy hoped.
Language: Английский
Citations
8Selective and Accurate Detection of Nitrate in Aquaculture Water with Surface-Enhanced Raman Scattering (SERS) Using Gold Nanoparticles Decorated with β-Cyclodextrins
Sensors, Journal Year: 2024, Volume and Issue: 24(4), P. 1093 - 1093
Published: Feb. 7, 2024
A surface-enhanced Raman scattering (SERS) method for measuring nitrate nitrogen in aquaculture water was developed using a substrate of β-cyclodextrin-modified gold nanoparticles (SH-β-CD@AuNPs). Addressing the issues low sensitivity, narrow linear range, and relatively poor selectivity single metal SERS detection nitrogen, we combined with cyclodextrin supramolecular compounds to prepare AuNPs enveloped by cyclodextrin, which exhibits ultra-high activity. Subsequently, vanadium(III) chloride used convert ions into nitrite ions. The adsorption mechanism between reaction product benzotriazole (BTAH) o-phenylenediamine (OPD) on SH-β-CD@AuNPs studied through SERS, achieving simultaneous nitrogen. experimental results show that BTAH distinct characteristic peaks at 1168, 1240, 1375, 1600 cm
Language: Английский
Citations
6Impact of different lactic acid bacteria on nitrite degradation and quality of fermented carrot
International Journal of Food Science & Technology, Journal Year: 2024, Volume and Issue: 59(9), P. 6501 - 6512
Published: Aug. 2, 2024
Summary In this study, six groups of carrots were designed and fermented using Weissella paramensenteroides MbWp142 (WP), Levilactobacillus brevis GDMCC 1.773 (LS), Leuconostoc mesenteroides 1.774 (SE), mixed fermentation three lactic acid bacteria (WP + LS SE), pasteurisation group (BG) natural (CK). GC–MS results indicated that inoculation WP SE increased the types contents flavour substances such as alcohols, esters hydrocarbons. Compared with other experimental groups, peak nitrite value in was lower due to production organic acids by bacteria. Sensory evaluation revealed quality carrot superior those SE, SE. Therefore, used a starter for fermenting can enhance product reduce accumulation during fermentation.
Language: Английский
Citations
5Evaluation of potential human health risks arising from nitrate and fluoride in the groundwater of Aurangabad, Bihar using GIS and chemometric analysis
Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(8)
Published: July 2, 2024
Language: Английский
Citations
4Development of a rapid sensor system for nitrate detection in water using enhanced Raman spectroscopy
RSC Advances, Journal Year: 2025, Volume and Issue: 15(8), P. 5728 - 5736
Published: Jan. 1, 2025
Nitrate is a primary source of nitrogen pollution in aquatic environments, making timely monitoring its levels surface and drinking water essential for environmental protection public health. Conventional laboratory methods are time-consuming require specialized expertise, while chemical electrode-based online detection systems hindered by challenges-such as frequent calibration ion cross-interference-which limits their suitability long-term monitoring. To address these limitations, novel nitrate method, utilizing an enhanced Raman spectroscopy device, was developed to rapidly detect water. The incorporation optical feedback mechanism significantly improved sensitivity, achieving limit 2.89 mg per L N, with single sample analysis completed under one minute. Furthermore, compact portable system designed integrating the enhancement device handheld spectrometer, which successfully validated using real-world samples. proposed features streamlined user design user-friendly operation, offering innovative approach rapid early warning. It also provides foundation establishing continuous quality.
Language: Английский
Citations
0Nitric Oxide in the Hypnotizability-Related Interoception: A Scoping Review
International Journal of Clinical and Experimental Hypnosis, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 19
Published: March 10, 2025
Interoception - the sense of body includes perception visceral signals and its integration with many other information in central nervous system. Hypnotizability levels are associated interoceptive accuracy sensitivity, likely due to different insula gray matter volume, availability vascular nitric oxide during sensory cognitive tasks peripheral arteries brain. This theoretical review deals relevance possible hypnotizability-related at various system interoception and, consequently, physiological pathological conditions, such as emotion, sleep disturbance, eating behavior, cardiovascular illness. Moreover, suggests that hypnotic assessment could be a predictor efficacy therapies based on improvement interoception.
Language: Английский
Citations
0In Vitro, Ex Vivo, and In Vivo Evidence of Nitrate-Reducing Activity in Levilactobacillus brevis CD2: A Potential Tool for Oral and Systemic Health Applications
Foods, Journal Year: 2025, Volume and Issue: 14(9), P. 1512 - 1512
Published: April 26, 2025
Growing evidence supports the use of nitrate-reducing bacterial strains as probiotics to enhance benefits nitrate metabolism for both oral and systemic health. This study aimed test reductase activity Levilactobacillus brevis CD2 (DSM-27961/CNCM I-5566), a strain widely used starter culture in fermented foods recognized its multifaceted health-promoting probiotic properties. We also sought determine whether lysate enhances reduction ex vivo using six salivary samples from healthy subjects while evaluating potential influence on pH buffering capacity. Considering established link between lactate nitrite production, we assessed levels D-lactate after 3-hour incubation with or without Lv. brevis. The results indicate that exhibits significant intrinsic concentration-dependent activity. Additionally, treatment 3 h significantly increased generation across all saliva samples, further enhancement observed addition exogenous nitrates. improved capacity, particularly when combined nitrate. Furthermore, resulted reduced D-lactate. To support validate our vitro findings, evaluated individuals treated four weeks lozenges. Of note, indicated group showed increase capacity compared baseline placebo treatment. Overall, suggests acts probiotic, providing new insights into health complementing findings previous studies.
Language: Английский
Citations
0Evaluation of irrigation, drinking, and risk indices for water quality parameters of alpine lakes
Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(5)
Published: April 15, 2024
Language: Английский
Citations
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