Association of waist circumference with blood pressure and familial dietary habits in preschool children: a cross-sectional study in northeastern China

˜The œItalian Journal of Pediatrics/Italian journal of pediatrics, Journal Year: 2022, Volume and Issue: 48(1)

Published: April 1, 2022

Childhood obesity increases the risk of elevated blood pressure (BP) in children. Body mass index (BMI), waist circumference (WC) and waist-to-height ratio (WHtR) are traditional indices, but extent to which these indices associated with BP childhood remains debatable. Moreover, familial dietary environment plays an important role obesity, so it is necessary determine most relevant factors for prevent BP. Our study aimed identify that closely then independent those indices. A total 605 children aged 2 6 years, as well their parents, were involved this study. The weight, height, WC measured. Information on environments was obtained by questionnaires completed parents. BMI, WHtR standardized into z scores, categorical variables three defined BMI Category, Category Category. Logistic regression used analyse associations between all Multivariate linear logistic Parental birth eating wheat a staple food, appetite, speed, snacking while watching TV, parental encouragement eat diverse assortment foods drinking milk independently both males females. abdominal increased 1.375 times 1.631 females if appetite one level. If speed level, 1.165 0.905 Females who drank more than per week had 0.546 lower obesity. anthropometric parameter In addition genetics, some involving preference, habits feeding practice preschool

Language: Английский

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Uric acid could be a marker of cardiometabolic risk and disease severity in children with juvenile idiopathic arthritis

European Journal of Pediatrics, Journal Year: 2022, Volume and Issue: 182(1), P. 149 - 154

Published: Oct. 14, 2022

Language: Английский

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Pediatric vs. adult NAFLD to MAFLD transition: a welcome but tangled path

Exploration of Medicine, Journal Year: 2021, Volume and Issue: unknown

Published: Aug. 16, 2021

The term non-alcoholic fatty liver disease (NAFLD) appears unfitting both in adults and children. As obesity metabolic syndrome play a relevant pathogenic role, an international group of adults’ experts has proposed to rename this condition (dysfunction)-associated (MAFLD). While new more appropriate useful definition mostly been met with good reactions adults, it may present tangled path pediatrics. Here we further stress the recommendations North American European Societies for Pediatric Gastroenterology, Hepatology Nutrition that hyperechogenic child affected by or overweight chronically elevated enzymes should not be assumed have NAFLD only. Especially those patients who are classic age range particularly severe laboratory anomalies, other genetic, (inborn errors metabolism, IEM), endocrine, intestinal hepatic pediatric-onset conditions, fact excluded, when response weight loss trial is available. pediatric (PeFLD) three subtypes (1. contextual diagnosis IEM; 2. Metabolic liver; 3. unknown cause liver) recently aiming separate true MAFLD from IEM and/or above mentioned which rare considered individually but represent large collectively. Although cost-effectiveness ratio attitude still indeterminate, likely advantage early identification specifically treatable associated to/mimicking would rewarding.

Language: Английский

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Association between Hepatic Steatosis and Obstructive Sleep Apnea in Children and Adolescents with Obesity

Children, Journal Year: 2021, Volume and Issue: 8(11), P. 984 - 984

Published: Nov. 1, 2021

Owing to the increasing rate of pediatric obesity, its complications such as non-alcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) have become prevalent already in childhood. We aimed assess relationship between these two diseases a cohort children with obesity.We enrolled 153 obesity (mean age 10.5 ± 2.66, mean BMI 30.9 5.1) showing OSA. Subjects underwent laboratory evaluation, cardio-respiratory polysomnography (PSG), ultrasound.All subjects had clinical diagnosis OSA based on AHI > 1/h 8.0 5.9; range 2.21-19.0). Of these, 69 showed hepatic steatosis (62.3% mild, 20.3% moderate, 17.4% severe degree). A strong association ALT apnea/hypopnea index (AHI) was observed (p = 0.0003). This not confirmed after adjusting for 0.53). By subdividing our population according presence/absence steatosis, this found only group 0.009). As severity increased, significance compared absence became progressively stronger (all p < 0.0001).Hepatic seems drive levels, suggesting potential pathogenic role NAFLD.

Language: Английский

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The efficacy of L-carnitine in patients with nonalcoholic steatohepatitis and concomitant obesity

Lipids in Health and Disease, Journal Year: 2023, Volume and Issue: 22(1)

Published: July 12, 2023

Abstract Background In light of the high prevalence nonalcoholic fatty liver disease and obesity, treatment options for steatohepatitis are particular interest. The purpose study is to assess efficacy L-carnitine its effects on functional state liver, as well lipid carbohydrate metabolism in patients with concomitant obesity. Methods People control group followed a hypocaloric diet received 1 tablet simvastatin 20 mg once day 2 capsules essential phospholipids 600 three times 90 days. experimental 10 mL orally two Results normalized blood profile subjects, demonstrated by significant decrease levels total cholesterol, triglycerides, low-density lipoproteins, atherogenic index, insulin resistance. use obesity contributes steady reduction main clinical biochemical symptoms steatohepatitis. Conclusions produces positive metabolism.

Language: Английский

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