Food Bioscience, Journal Year: 2023, Volume and Issue: 57, P. 103466 - 103466
Published: Dec. 17, 2023
Language: Английский
Food Chemistry, Journal Year: 2024, Volume and Issue: 460, P. 140533 - 140533
Published: July 20, 2024
Language: Английский
Citations
5
Obesity Pillars, Journal Year: 2023, Volume and Issue: 7, P. 100070 - 100070
Published: May 18, 2023
Language: Английский
Citations
11
Chemistry Africa, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 18, 2025
Language: Английский
Citations
0
Obesity Pillars, Journal Year: 2025, Volume and Issue: unknown, P. 100172 - 100172
Published: March 1, 2025
This collaboration from the Obesity Medicine Association (OMA) and American College of Osteopathic Family Physicians (ACOFP) examines obesity management a primary care perspective. joint perspective is based upon scientific evidence, clinical experience authors, peer review by OMA ACOFP leadership. The goal to identify answer sentinel questions about perspective, utilizing evidence-based publications, guided expert experience. disease that contributes both biomechanical complications most common cardiometabolic abnormalities encountered in care. Barriers impede optimal patients with include failure recognize as disease, lack accurate diagnosis, insufficient access treatment resources, inadequate training, time, adequate reimbursement adverse impact bias, stigma, discrimination. physicians are often first line healthcare setting. affords early intervention opportunities prevent and/or treat overweight obesity. Patient enhanced when clinicians risks benefits anti-obesity medications bariatric procedures, well long-term follow-up. Practical tools regarding 4 pillars nutrition therapy, physical activity, behavior modification, medical interventions (anti-obesity surgery) may assist improve health lives living
Language: Английский
Citations
0
Diabetes Metabolic Syndrome and Obesity, Journal Year: 2025, Volume and Issue: Volume 18, P. 805 - 818
Published: March 1, 2025
Proteomics was used to study the effect of semaglutide on expression renal protein in obese mice, and looking for proteins that could improve prognosis Kidney Renal Clear Cell Carcinoma (KIRC). Thirty-six mice were randomly divided into normal-fat diet group (NFD), high-fat (HFD), plus intervention (HS). Collected serum, urine, kidney tissue samples, detected urinary protein/creatinine, blood glucose, lipid, inflammation, oxidative stress other related indicators. Different staining methods analyze pathological changes mice's kidneys. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis total kidneys mice. Finally, bioinformatics technology significantly different expressed (DEPs). The mechanism protecting phosphorylation, PPAR signaling pathway, thiamine, butyric acid tryptophan metabolism pathways. Moreover, increase Man1a1 Ntn4 while high-expression KIRC population had a better overall survival rate. Semaglutide regulate development by up-adjusting Ntn4.
Language: Английский
Citations
0
Obesity Pillars, Journal Year: 2023, Volume and Issue: 7, P. 100076 - 100076
Published: June 13, 2023
A common adiposopathic complication of obesity is type 2 diabetes mellitus. Healthful weight reduction in patients with can improve glucose metabolism and potentially promote remission However, weight-reduction increased adiposity impaired among mellitus compared to without Data for this review were derived from PubMed appliable websites. Among body fat, the mechanisms underlying those are multifactorial, include energy conservation (i.e., improved control reduced glucosuria), hyperinsulinemia (commonly found many mellitus), potential use obesogenic anti-diabetes medications, contributions multiple systems. Other factors age, sex, genetic/epigenetic predisposition, environments. Even though impairs adiposity, clinically meaningful improves sometimes remission. An illustrative approach mitigate due choosing medications that increase insulin sensitivity loss deprioritize exposure gain.
Language: Английский
Citations
10
Brazilian Journal of Science, Journal Year: 2024, Volume and Issue: 3(2), P. 66 - 81
Published: Feb. 1, 2024
Several genetic expressions have been involved in the development of cancer such as expression a ribosomal kinase S6 P90 (RSK-4). It is important to mention that some compounds LJH685, 2073047-06-8, and SL0101 can act RSK-4 inhibitors; however, its interaction with surface very confusing. The aim this research was evaluate twenty-nine steroid derivatives (1 29) using 6rv2 protein, 2073047-06-8 theoretical tools Dockingserver program. results showed differences aminoacid residues protein compared SL0101. Besides, inhibition constant for 1, 12, 14, 19 22 lower drug. In conclusion, could be good alternative inhibitors decrease cells growth.
Language: Английский
Citations
3
Obesity Pillars, Journal Year: 2022, Volume and Issue: 4, P. 100039 - 100039
Published: Oct. 25, 2022
Historically, many anti-obesity medications (AOMs) were withdrawn from development and/or the market due to safety concerns. Another challenge was that, with some exceptions, most of these AOMs had limited weight reducing efficacy. Approved often did not meet reduction expectations either clinicians, or their patients. Currently, newer approved and investigational achieve greater than older AOMs. This has prompted an emerging new "too much loss" highly effective (heAOM) - something think possible prior year 2020.
Language: Английский
Citations
16
Obesity Pillars, Journal Year: 2022, Volume and Issue: 4, P. 100041 - 100041
Published: Nov. 4, 2022
Language: Английский
Citations
14
Obesity Pillars, Journal Year: 2022, Volume and Issue: 4, P. 100044 - 100044
Published: Nov. 18, 2022
Language: Английский
Citations
14