Advances in artificial intelligence for drug delivery and development: A comprehensive review

Computers in Biology and Medicine, Journal Year: 2024, Volume and Issue: 178, P. 108702 - 108702

Published: June 7, 2024

Language: Английский

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Microfluidics for personalized drug delivery

Drug Discovery Today, Journal Year: 2024, Volume and Issue: 29(4), P. 103936 - 103936

Published: Feb. 29, 2024

This review highlights the transformative impact of microfluidic technology on personalized drug delivery. Microfluidics addresses issues in traditional synthesis, providing precise control and scalability nanoparticle fabrication, platforms show high potential for versatility, offering patient-specific dosing real-time monitoring capabilities, all integrated into wearable technology. Covalent conjugation antibodies to nanoparticles improves bioactivity, driving innovations targeting. The integration microfluidics with sensor technologies artificial intelligence facilitates feedback autonomous adaptation delivery systems. Key challenges, such as droplet polydispersity fluidic handling, along future directions focusing reliability, are essential considerations advancing

Language: Английский

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Application of response surface and artificial neural network optimization approaches for exploring methylene blue adsorption using luffa fiber treated with sodium chlorite

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 58, P. 104778 - 104778

Published: Jan. 8, 2024

Language: Английский

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Next-Generation Therapeutic Antibodies for Cancer Treatment: Advancements, Applications, and Challenges

Molecular Biotechnology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 2, 2024

Language: Английский

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Size prediction of drug-loaded Polymeric (PLGA) microparticles prepared by microfluidics

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 98, P. 105776 - 105776

Published: June 1, 2024

Language: Английский

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Liposomes and Niosomes: New trends and applications in the delivery of bioactive agents for cancer therapy

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 124994 - 124994

Published: Nov. 1, 2024

Language: Английский

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Validation of Velocity in Microchannels with a Retention System due to Unevenness Manufactured by 3D Printing (SLA)

Defect and diffusion forum/Diffusion and defect data, solid state data. Part A, Defect and diffusion forum, Journal Year: 2025, Volume and Issue: 439, P. 243 - 260

Published: Feb. 20, 2025

Microfluidics is an efficient technology for controlling fluid movement in microchannels at extremely low speeds. The main advantage lies the significant reduction of samples and reagents, thereby reducing costs analysis times. Three devices with retention systems are introduced that manufactured through 3D printing (SLA) incorporating variations levels dimensions. Fluid velocity studied, considering factors such as channel width, length, rounding, height, shape. along reveals liquid devices' maximum point, ensuring more precise results microdevices.

Language: Английский

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Flow Pattern Identification and Detection in T-Junction Microchannels for Shear Thinning Non-Newtonian Fluids

Published: Jan. 1, 2025

Language: Английский

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Recent Advances and Challenges for Biological Materials in Micro/Nanocarrier Synthesis for Bone Infection and Tissue Engineering

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Roughly 1.71 billion people worldwide suffer from large bone abnormalities, which are the primary cause of disability. Traditional grafting procedures have several drawbacks that impair their therapeutic efficacy and restrict use in clinical settings. A great deal work has been done to create fresh, more potent strategies. Under these circumstances, a crucial technique for regeneration major lesions emerged: tissue engineering (BTE). BTE involves biomaterials can imitate natural design bone. To yet, no biological material able fully meet parameters perfect implantable material, even though varieties created investigated regeneration. Against this backdrop, researchers focused interest over past few years on subject nanotechnology nanostructures regenerative medicine. The ability nanoengineered particles overcome current constraints strategies─such as decreased cell proliferation differentiation, insufficient mechanical strength materials, production extrinsic factors required effective osteogenesis revolutionized field engineering. effects nanoparticles characteristics application materials main topics our review, summarizes most recent vitro vivo research context BTE.

Language: Английский

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Direct sensing of temperature dependence of electric field and conductivity of liquids using glass microelectrodes

AIP Advances, Journal Year: 2025, Volume and Issue: 15(4)

Published: April 1, 2025

In recent years, ionic current analyses for liquid environments have attracted significant attention. Ionic responses obtained from confined small spaces provide information and new findings the viewpoint of micro- nano-scales. Signals in such are weak often disturbed by noise, thus, measurement technique liquids has been an important issue. Herein, we developed a novel to directly measure electric field test section, which enables us determine electrical conductivity concentration. Upon scanning glass microelectrode, spatial distribution is visualized. this study, temperature dependence analyzed range 303 333 K, using LiCl, NaCl, KCl solutions. The relationship between field, conductivity, viscosity discussed. summary, microelectrode shown enable quantitative analysis physical properties spatially localized temperature-dependent quantities.

Language: Английский

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