Conventional and innovative approaches to black fungi control for stone heritage preservation DOI Creative Commons
Domenico Celi, Massimiliano Marvasi, Brunella Perito

et al.

IUBMB Life, Journal Year: 2025, Volume and Issue: 77(3)

Published: March 1, 2025

Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups microorganisms causing deterioration outdoor exposed stone monuments mainly due to formation dark spots patches leading darkening their surface, cracking, bio-pitting. among stress-resistant organisms on Earth, known for remarkable ability withstand solar radiation, desiccation, extreme temperature fluctuations, which has led widespread distribution across globe. These features make very difficult remove restrict, representing challenge restorers. Despite number scientific works about isolation ecology, little is response antimicrobial treatments. Conventional biocides remain used treatment control biodeterioration artworks. In recent years, interest in alternative safer treatments risen conservation strategies. The efficacy against evaluated is, however, still low. aim this review assess existing studies regarding both conventional innovative This will encompass in-depth examination methodologies application evaluation Furthermore, we highlight future research directions that contribute more informed selection effective anti-BMF interventions preservation. We underscore significance pioneering, environmentally low-impact solutions.

Language: Английский

Carvacrol and thymol effect in vapor phase on Escherichia coli and Salmonella serovar Typhimurium growth inoculated in a fresh salad DOI Creative Commons
Teresa Soledad Cid-Pérez,

Ricardo Munguía-Pérez,

Guadalupe Virginia Nevárez‐Moorillón

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(9), P. e29638 - e29638

Published: April 16, 2024

This study aimed to evaluate the antimicrobial effect of thymol and carvacrol in inhibiting

Language: Английский

Citations

5
Thymol, a Monoterpenoid within Polymeric Iodophor Formulations and Their Antimicrobial Activities DOI Open Access
Zehra Edis, Samir Haj Bloukh

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(9), P. 4949 - 4949

Published: May 1, 2024

Antimicrobial resistance (AMR) poses an emanating threat to humanity’s future. The effectiveness of commonly used antibiotics against microbial infections is declining at alarming rate. As a result, morbidity and mortality rates are soaring, particularly among immunocompromised populations. Exploring alternative solutions, such as medicinal plants iodine, shows promise in combating resistant pathogens. Such antimicrobials could effectively inhibit proliferation through synergistic combinations. In our study, we prepared formulation consisting Aloe barbadensis Miller (AV), Thymol, iodine (I2), polyvinylpyrrolidone (PVP). Various analytical methods including SEM/EDS, UV-vis, Raman, FTIR, XRD were carried out verify the purity, composition, morphology AV-PVP-Thymol-I2. We evaluated inhibitory effects this 10 selected reference strains using impregnated sterile discs, surgical sutures, gauze bandages, face masks, KN95 masks. antimicrobial properties AV-PVP-Thymol-I2 assessed disc diffusion comparison with two common antibiotics. 25-month-old exhibited slightly lower zones, indicating changes sustained-iodine-release reservoir. Our findings confirm potent antifungal antibacterial agent strains, demonstrating strong action on cotton These results enable potential use promising wound spray-on contact-killing agent.

Language: Английский

Citations

5
Antibacterial Potential of Essential Oils and Silver Nanoparticles against Multidrug-Resistant Staphylococcus pseudintermedius Isolates DOI Creative Commons
Gabriele Meroni, Giulia Laterza, Alexios Tsikopoulos

et al.

Pathogens, Journal Year: 2024, Volume and Issue: 13(2), P. 156 - 156

Published: Feb. 9, 2024

Staphylococcus pseudintermedius is an emergent zoonotic agent associated with multidrug resistance (MDR). This work aimed to describe the antibacterial activity of four essential oils (EOs) and silver nanoparticles (AgNPs) against 15 S. strains isolated from pyoderma. The EOs, namely Rosmarinus officinalis (RO), Juniperus communis (GI), Citrus sinensis (AR), Abies alba (AB), AgNPs were used alone in combination determine Minimum Inhibitory Concentration (MIC) Bactericidal (MBC). All MDR methicillin-resistant. Among antibiotic cohort, only rifampicin, doxycycline, amikacin effective. EOs’ chemical analysis revealed 124 compounds belonging various classes. Of them, 35 found AR, 75 AB, 77 GI, 57 RO. monoterpenic fraction prevailed over sesquiterpenic all EOs. When EOs tested alone, AB showed lowest MIC followed by RO (with values ranging 1:128 1:2048). MBC increased following order: 1:512 for 10.74 mg/L ± 4.23 261.05 172.74. In conclusion, could limit use antibiotics or improve efficacy conventional therapies.

Language: Английский

Citations

4
Thymol as Starting Material for the Development of a Biobased Material with Enhanced Antimicrobial Activity: Synthesis, Characterization, and Potential Application DOI Creative Commons
Giovana A. Parolin, Vitor Gonçalves Vital, Suzan Pantaroto de Vasconcellos

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 1010 - 1010

Published: Feb. 26, 2024

A biobased material, polythymol (PTF), was prepared using thymol, a monoterpene obtained from the essential oil of Thymus vulgaris (Lamiaceae), as starting material with aim enhancing antimicrobial properties this natural product. Initially, different processes were performed in order to optimize reaction conditions obtain macromolecule high purity and yield. PTF characterized techniques, such NMR, infrared, UV-Vis, thermogravimetric analyses. The activity both thymol evaluated against microorganisms, including S. aureus, E. coli, P. aeruginosa, C. albicans. MIC values showed higher potential for than monomer thymol—for example, aureus (500 31.5 µg·mL−1 PTF, respectively). Therefore, results show that polymerization afforded more active biomaterial monomeric compound (thymol), suggesting is an important biomaterial.

Language: Английский

Citations

4
Flow cytometry: Unravelling the real antimicrobial and antibiofilm efficacy of natural bioactive compounds DOI
Valeria Poscente, Luciana Di Gregorio, Manuela Costanzo

et al.

Journal of Microbiological Methods, Journal Year: 2024, Volume and Issue: 222, P. 106956 - 106956

Published: May 15, 2024

Language: Английский

Citations

4
Fabrication, characterization, and application of complex essential oils loaded bilayer films using PLA and pickering emulsions with SPI-chitosan nanoparticles as solid support DOI
Liangliang Zhang, Yi Hou, Saisai Feng

et al.

Food Packaging and Shelf Life, Journal Year: 2025, Volume and Issue: 47, P. 101426 - 101426

Published: Jan. 1, 2025

Language: Английский

Citations

0
Essential Oils as Antimicrobials against Acinetobacter baumannii: Experimental and Literature Data to Definite Predictive Quantitative Composition–Activity Relationship Models Using Machine Learning Algorithms DOI
Roberta Astolfi, Alessandra Oliva, Antonio Raffo

et al.

Journal of Chemical Information and Modeling, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Essential oils (EOs) exhibit a broad spectrum of biological activities; however, their clinical application is hindered by challenges, such as variability in chemical composition and chemical/physical instability. A critical limitation the lack consistency across EO samples, which impedes standardization. Despite this, evidence suggests that EOs with differing profiles often display similar (micro)biological activities, raising possibility standardizing based on effects rather than composition. This study explored relationship between antibacterial activity against carbapenem-resistant Acinetobacter baumannii. dataset comprising 82 known minimal inhibitory concentration values was compiled using both experimental results literature data sourced from AI4EssOil database (https://www.ai4essoil.com). Machine learning classification algorithms including Support Vector Machines, Random Forest, Gradient Boosting, Decision Trees, K-Nearest Neighbors were employed to generate quantitative composition–activity models. Model performance assessed internal external prediction accuracy metrics Matthews correlation coefficient primary evaluation metrics. Features importance analysis, Skater methodology, identified key components influencing activity. The single limonene, eucalyptol, alpha-pinene, linalool, beta-caryophyllene, nerol, beta-pinene, neral, carvacrol highlighted efficacy. predictive capacity ML models validated test set freshly extracted chemically characterized EOs. demonstrated 91% for new strong observed predicted features six selected pure compounds (limonene, carvacrol, thymol). Additionally, machine approach extended cytotoxicity 3T3-Swiss fibroblasts 61 analysis revealed potential design high low through blending or selective enrichment components. These findings pave way biologically standardized EOs, enabling rational optimization applications.

Language: Английский

Citations

0
Ecologically benign synthesis of thyme polyphenolic bioactive compounds loaded Poly(vinyl Alcohol)/Sodium Alginate sponges for sustainable point-of-use applications. Characterization and inactivation of waterborne pathogens in water disinfection DOI
Hany M. Abd El‐Lateef, Mai M. Khalaf, Mustapha Taleb

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 115704 - 115704

Published: Feb. 1, 2025

Language: Английский

Citations

0
Enhanced Pathogen Control Through Thymol and Carvacrol Nanoemulsions: A Microfluidization Approach DOI Creative Commons
Yeşim Özoğul, Gokcem Tonyali Karsli, Hatice Yazgan

et al.

Food and Bioprocess Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 17, 2025

Language: Английский

Citations

0
Antibacterial and Biodegradable PLA-based Nanofibers Loaded with Natural Phenolic Monoterpenes for Sustainable Biomedical or Food Application DOI Creative Commons
Lucie Bartošová, Magda Janalí­ková, Jana Sedlaříková

et al.

New Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Antibacterial biodegradable PLA-based nanofibers loaded with phenolic monoterpenes - thymol, eugenol, carvacrol, and cinnamaldehyde, were prepared by electrospinning. The effect of bioactive molecule on the surface, thermal, morphological, biological properties has been investigated about potential pharmaceutical food processing applications. Fiber diameters ranged from 320nm for PLA fibrous mat up to 480nm membrane 6% thymol. All active exhibited hydrophobic surfaces a slightly decreasing contact angle after incorporation phenols. Antimicrobial testing proved strong efficiency against Escherichia coli Staphylococcus aureus, depending specific type content compound. A significant biofilm formation reduction was revealed tested microorganisms. Modification fibers molecules did not significantly affect biodegradation kinetics in comparison samples their absence. This study demonstrates high newly developed PLA-based/phenol nanofibrous membranes use as antibacterial antifouling systems applicable wound dressings packaging.

Language: Английский

Citations

0