Keratin-Positive Giant Cell-Rich Tumor: A Review and Update

Cancers, Journal Year: 2024, Volume and Issue: 16(10), P. 1940 - 1940

Published: May 20, 2024

Keratin-positive giant cell-rich tumor (KPGCT) is an extremely rare and recently described mesenchymal neoplasm that occurs in both soft tissue bone, frequently found young women. It has locally recurrent potential if incompletely excised but low risk for metastasis. KPGCT histologically similar to conventional cell tumors of shows the presence keratin-positive mononuclear cells. Interestingly, also shares some morphological features with xanthogranulomatous epithelial tumors. These two have been shown harbor HMGA2–NCOR2 fusion, arguing favor a single entity. Surgery treatment choice localized KPGCT. Therapeutic options advanced or metastatic disease are unknown. This review provides overview current knowledge on clinical presentation, pathogenesis, histopathology, In addition, we will discuss differential diagnosis this emerging

Language: Английский

Xanthogranulomatous epithelial tumors/keratin-positive giant cell–rich tumors involving the head and neck: report of seven cases and review of the literature

Virchows Archiv, Journal Year: 2024, Volume and Issue: 485(4), P. 605 - 613

Published: Aug. 20, 2024

Language: Английский