JCO Oncology Practice,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 10, 2025
PURPOSE
The
purpose
ot
this
study
was
to
assess
the
effectiveness
of
an
educational
video
compared
in-person
genetic
counseling
for
cancer
testing
candidates.
Genetic
risk
assessment
is
essential
tailoring
oncological
treatment,
identifying
individuals
at
higher
cancer,
implementing
risk-reduction
strategies,
and
enabling
family
cascade
testing.
Pretest
facilitates
individual’s
informed
decision
making
reduces
anxiety.
However,
availability
genetics
specialists
limited
in
constrained
resource
settings.
METHODS
We
conducted
a
randomized
controlled
noninferiority
clinical
trial
comparing
(intervention
arm)
with
(control
main
outcome
acceptance,
requiring
95%
CI
around
intervention
difference
be
less
than
(–)10
percentage
points
claim
noninferiority.
Secondary
outcomes
included
knowledge,
anxiety,
satisfaction.
RESULTS
250
participants
who
met
criteria
testing,
mean
age
47.9
years
(standard
deviation,
12.7);
86.4%
were
women.
All
both
arms
accepted
(difference
=
0%
[95%
CI,
–0.04%
0%];
P
1.0).
Knowledge
improved
groups:
score
increments
20
(95%
16
24;
<
.05)
control
arm
12
20;
arm.
Anxiety
scores
decreased:
–0.58
–0.09
–1.08;
.01)
–0.75
–0.42
–0.08;
Satisfaction
levels
97.5%
92.5%,
respectively
(
.34).
CONCLUSION
noninferior
improves
These
findings
support
using
videos
address
shortage
professionals.
Frontiers in Artificial Intelligence,
Journal Year:
2023,
Volume and Issue:
6
Published: Oct. 31, 2023
The
release
of
ChatGPT
has
initiated
new
thinking
about
AI-based
Chatbot
and
its
application
drawn
huge
public
attention
worldwide.
Researchers
doctors
have
started
the
promise
AI-related
large
language
models
in
medicine
during
past
few
months.
Here,
comprehensive
review
highlighted
overview
their
current
role
medicine.
Firstly,
general
idea
Chatbots,
evolution,
architecture,
medical
use
are
discussed.
Secondly,
is
discussed
with
special
emphasis
medicine,
architecture
training
methods,
diagnosis
treatment,
research
ethical
issues,
a
comparison
other
NLP
illustrated.
article
also
limitations
prospects
ChatGPT.
In
future,
these
will
immense
healthcare.
However,
more
needed
this
direction.
Interactive Technology and Smart Education,
Journal Year:
2023,
Volume and Issue:
21(2), P. 189 - 213
Published: March 27, 2023
Purpose
The
application
of
artificial
intelligence
chatbots
is
an
emerging
trend
in
educational
technology
studies
for
its
multi-faceted
advantages.
However,
the
existing
rarely
take
a
perspective
to
evaluate
contexts.
This
study
aims
bridge
research
gap
by
taking
review
literature
on
chatbots.
Design/methodology/approach
combines
bibliometric
analysis
and
citation
network
analysis:
through
visualization
keyword,
authors,
organizations
countries
based
clustering.
Findings
Educational
applications
are
still
rising
post-COVID-19
learning
environments.
Popular
issues
this
topic
include
technological
advancements,
students’
perception
effectiveness
different
Originating
from
similar
theoretical
foundations,
primarily
applied
language
education,
services
(such
as
information
counseling
automated
grading),
health-care
education
medical
training.
Diversifying
contexts
demonstrate
specific
purposes
using
but
confronted
with
some
common
challenges.
Multi-faceted
factors
can
influence
acceptance
education.
provides
extended
framework
facilitate
extending
chatbot
Research
limitations/implications
authors
have
acknowledge
that
subjected
limitations.
First,
search
was
core
collection
Web
Science,
which
did
not
studies.
Second,
only
included
published
English.
Third,
due
limitation
expertise,
could
comprehensively
interpret
implications
reporting
advancements.
intended
establish
significance
summarizing
evaluating
perspective.
Originality/value
identifies
publication
trends
It
bridges
caused
previous
neglection
treating
interconnected
whole
characteristics.
major
encouraged
further
applications.
also
proposes
consider
covers
three
critical
components
integration
when
future
researchers
instructors
apply
new
JAMA Oncology,
Journal Year:
2024,
Volume and Issue:
10(7), P. 956 - 956
Published: May 16, 2024
Artificial
intelligence
(AI)
chatbots
pose
the
opportunity
to
draft
template
responses
patient
questions.
However,
ability
of
generate
based
on
domain-specific
knowledge
cancer
remains
be
tested.
Journal of Genetic Counseling,
Journal Year:
2022,
Volume and Issue:
31(5), P. 1219 - 1230
Published: May 26, 2022
Abstract
Successful
proband‐mediated
family
communication
and
subsequent
cascade
genetic
testing
uptake
requires
interventions
that
present
information
clearly,
in
sufficient
detail,
with
medical
authority.
To
facilitate
for
patients
receiving
clinically
actionable
results
via
the
MyCode®
Community
Health
Initiative,
a
Family
Sharing
Tool
(FST)
chatbot
were
developed.
FST
is
an
electronic
mechanism
allowing
to
share
test
relatives
chatbot.
The
describes
proband's
result,
associated
disease
risks,
recommended
management
captures
whether
user
blood
relative
or
caregiver,
sex,
relationship
proband.
among
probands
was
tracked
from
August
2018
through
February
2020.
Cascade
collected
laboratories
as
number
of
cascades
per
Fifty‐eight
percent
(316/543)
consented
FST;
42%
(227/543)
declined.
Receipt
preferences
patient
health
record
(EHR)
portal
(52%),
email
(29%),
text
(19%).
Patient
EHR
users
(
p
<
0.001)
younger
more
likely
consent
0.001).
deployed
308
probands.
Fifty‐nine
(183/308)
opened;
those,
56%
(102/183)
used
send
relatives.
These
102
shared
377
Sixty‐two
(235/377)
these,
69%
(161/235)
started,
57%
(92/161)
completed
significantly
greater
who
M
=
2.34
cascades,
SD
2.10)
than
declined
1.40
0.82,
Proband
age
not
significant
predictor
uptake.
Further
work
needed
better
understand
factors
impacting
proband
use
chatbots.
International Journal of General Medicine,
Journal Year:
2023,
Volume and Issue:
Volume 16, P. 1591 - 1602
Published: May 1, 2023
Background:
Few
reports
have
investigated
chatbots
in
patient
care.
We
aimed
to
assess
the
current
applications,
limitations,
and
challenges
literature
on
employed
oncological
Methods:
queried
PubMed
database
through
April
2022
included
studies
that
use
of
different
phases
The
search
used
five
combinations
specific
terms
"chatbot",
"cancer",
"oncology",
"conversational
agent".
Inclusion
criteria
were
chatbot
any
aspect
care—prevention,
education,
treatment,
surveillance.
Results:
initial
yielded
196
records,
21
which
met
inclusion
criteria.
identified
mostly
focused
breast
ovarian
cancer
(n=8),
with
second
most
common
being
cervical
(n=3).
Good
satisfaction
was
reported
among
14
chatbots.
applications
screening,
prevention,
risk
stratification,
monitoring,
management.
Of
12
examining
efficacy
care
via
chatbot,
9
demonstrated
improvements
compared
standard
Conclusion:
Chatbots
for
date
demonstrate
high
user
satisfaction,
many
shown
improving
patient-centered
communication,
accessibility
cancer-related
information,
access
Currently,
are
primarily
limited
by
need
extensive
user-testing
iterative
improvement
before
widespread
implementation.
Keywords:
conversational
agent,
artificial
intelligence,
AI,
cancer,
oncology
American Journal of Medical Genetics Part C Seminars in Medical Genetics,
Journal Year:
2023,
Volume and Issue:
193(3)
Published: July 28, 2023
Abstract
The
transition
from
analog
to
digital
technologies
in
clinical
laboratory
genomics
is
ushering
an
era
of
“big
data”
ways
that
will
exceed
human
capacity
rapidly
and
reproducibly
analyze
those
data
using
conventional
approaches.
Accurately
evaluating
complex
molecular
facilitate
timely
diagnosis
management
genomic
disorders
require
supportive
artificial
intelligence
methods.
These
are
already
being
introduced
into
identify
variants
DNA
sequencing
data,
predict
the
effects
on
protein
structure
function
inform
interpretation
pathogenicity,
link
phenotype
ontologies
genetic
identified
through
exome
or
genome
help
clinicians
reach
diagnostic
answers
faster,
correlate
with
tumor
staging
treatment
approaches,
utilize
natural
language
processing
critical
published
medical
literature
during
analysis
use
interactive
chatbots
individuals
who
qualify
for
testing
provide
pre‐test
post‐test
education.
With
careful
ethical
development
validation
genomics,
these
advances
expected
significantly
enhance
abilities
geneticists
translate
clearly
synthesized
information
managing
care
their
patients
at
scale.
Journal of the American Medical Informatics Association,
Journal Year:
2024,
Volume and Issue:
31(10), P. 2271 - 2283
Published: June 14, 2024
To
evaluate
the
efficacy
of
ChatGPT
4
(GPT-4)
in
delivering
genetic
information
about
BRCA1,
HFE,
and
MLH1,
building
on
previous
findings
with
3.5
(GPT-3.5).
focus
assessing
utility,
limitations,
ethical
implications
using
medical
settings.
Universal Access in the Information Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 10, 2024
Abstract
Healthcare
is
one
of
the
most
important
sectors
our
society,
and
during
COVID-19
pandemic
a
new
challenge
emerged—how
to
support
people
safely
effectively
at
home
regarding
their
health-related
problems.
In
this
regard
chatbots
or
conversational
agents
(CAs)
play
an
increasingly
role,
are
spreading
rapidly.
They
can
enhance
not
only
user
interaction
by
delivering
quick
feedback
responses,
but
also
hospital
management,
thanks
several
features.
Considerable
research
focused
on
making
CAs
more
reliable,
accurate,
robust.
However,
critical
aspect
how
make
them
inclusive,
in
order
users
unfamiliar
with
technology,
such
as
elderly
disabilities.
study,
we
investigate
current
use
healthcare,
exploring
evolution
over
time
inclusivity.
The
study
was
carried
out
four
digital
libraries
(ScienceDirect,
IEEE
Xplore,
ACM
Digital
Library,
Google
Scholar)
articles
published
last
5
years,
total
21
describing
implemented
actually
used
eHealth
clinical
area.
results
showed
notable
improvement
few
years
highlight
some
design
issues,
including
poor
attention
inclusion.
Based
findings,
recommend
different
kind
approach
for
implementing
inclusive
accessibility-by-design
approach.
Current Oncology,
Journal Year:
2025,
Volume and Issue:
32(3), P. 145 - 145
Published: March 2, 2025
The
Artificial
Intelligence
Patient
Librarian
(AIPL)
was
designed
to
meet
the
psychosocial
and
supportive
care
needs
of
Metastatic
Breast
Cancer
(MBC)
patients
with
HR+/HER2−
subtypes.
AIPL
provides
conversational
patient
education,
answers
user
questions,
offers
tailored
online
resource
recommendations.
This
study,
conducted
in
three
phases,
assessed
AIPL’s
impact
on
patients’
ability
manage
their
advanced
disease.
In
Phase
1,
educational
content
adapted
for
chatbot
delivery,
over
100
credible
resources
were
annotated
using
a
Convolutional
Neural
Network
(CNN)
drive
2
involved
42
participants
who
completed
pre-
post-surveys
after
two
weeks.
surveys
measured
activation
Activation
Measure
(PAM)
tool
evaluated
experience
System
Usability
Scale
(SUS).
3
included
focus
groups
explore
experiences
depth.
Of
participants,
36
10
participating
groups.
Most
aged
40–64.
PAM
scores
showed
no
significant
differences
between
pre-survey
(mean
=
59.33,
SD
5.19)
post-survey
59.22,
6.16),
while
SUS
indicated
good
usability.
Thematic
analysis
revealed
four
key
themes:
basic
wellness
health
guidance,
limited
support
managing
relationships,
condition-specific
medical
information,
is
unable
offer
hope
patients.
Despite
showing
PAM,
possibly
due
high
baseline
activation,
demonstrated
usability
met
information
needs,
particularly
newly
diagnosed
MBC
Future
iterations
will
incorporate
large
language
model
(LLM)
provide
more
comprehensive
personalized
assistance.