Magnetic Nanoparticles: A Comprehensive Review from Synthesis to Biomedical Frontiers

Langmuir, Journal Year: 2024, Volume and Issue: 40(33), P. 17239 - 17269

Published: Aug. 12, 2024

Nanotechnology has opened new doors of exploration, particularly in materials science and healthcare. Magnetic nanoparticles (MNP), the tiny magnets, because their various properties, have potential to bring about radical changes field medicine. The distinctive surface chemistry, nontoxicity, biocompatibility, and, particular, inducible magnetic moment attracted a great deal interest morphological structures from variety scientific domains. This review presents concise overview MNPs crucial properties synthesis routes. It also aims highlight continuous methods available for MNP production. In recent years, use computational understanding behavior been on rise. Thus, we discuss numerical models developed understand how can be used hyperthermia targeting Circle Wilis. With increasing biomedical applications, it becomes necessary mechanisms toxicity, which are elucidated this review. focuses applications drug delivery, theranostics, MRI contrasting agents. We anticipate that article will broaden perspective help functionality applicability better.

Language: Английский

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Advancements of metallic nanoparticles: A promising frontier in cancer treatment

Science Progress, Journal Year: 2024, Volume and Issue: 107(4)

Published: Oct. 1, 2024

The incidence of cancer is increasing and evolving as a major source mortality. Nanotechnology has garnered considerable scientific interest in recent decades can offer promising solution to the challenges encountered with traditional chemotherapy. Nanoparticle utilization holds promise combating other diseases, offering exciting prospects for drug delivery systems medicinal applications. Metallic nanoparticles exhibit remarkable physical chemical properties, such their minute size, composition, structure, extensive surface area, rendering them versatile cost-effective. Research demonstrated significant beneficial impact on treatment, characterized by enhanced targeting abilities, gene activity suppression, improved efficiency. By incorporating ligands, functionalized metal ensure precise energy deposition within tumors, thereby augmenting treatment accuracy. Moreover, beyond therapeutic efficacy, serve valuable tools cell visualization, contributing diagnostic techniques. Utilizing allows simultaneous diagnosis while also facilitating controlled release, thus revolutionizing care. This narrative review investigates advancements types mechanisms cells, application clinical scenarios, potential toxicity medicine.

Language: Английский

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Antibacterial activity of green synthesized copper oxide nanoparticles against multidrug-resistant bacteria

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 23, 2024

Abstract Using plant extracts in the green synthesis of nanoparticles has become an environmentally acceptable approach. In our study, copper oxide (CuO NPs) were synthesized using ethanolic Azadirachta indica and Simmondsia chinensis . CuO NP formation was confirmed by change color UV‒visible spectroscopy NPs peaked at a wavelength 344 nm). TEM images semispherical shape NPs, with particle sizes ranging from 30.9 to 10.7 nm. The antibacterial activity these evaluated agar diffusion method against clinical isolates, including methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli , Pseudomonas aeruginosa Acinetobacter spp., Klebsiella pneumoniae Stenotrophomonas maltophilia minimum inhibitory concentration (MIC) ranged 62.5 125 µg/ml. contrast, antioxidant antibiofilm 31.1 92.2% 125–500 µg/ml 62.2–95%, respectively, –62.5 Our results that had IC50s 383.41 ± 3.4 402.73 1.86 250 µg/mL HBF4 cell line. Molecular docking studies suggested penicillin-binding protein 4 (PBP4) beta-lactamase proteins (OXA-48) strongly bind S. K. NPs. study confirms promising use treating pathogenic bacteria could be possible alternative antibiotics. This supports pharmaceutical healthcare sectors Egypt worldwide.

Language: Английский

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Eco-friendly synthesis of copper nanoparticles by using Ralstonia sp. and their antibacterial, anti-biofilm, and antivirulence activities

Biochemistry and Biophysics Reports, Journal Year: 2025, Volume and Issue: 42, P. 101978 - 101978

Published: March 13, 2025

Language: Английский

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Advances in nanoarchitectonics of metal-organic frameworks and metal-/metalloid-containing nanomaterials for antibacterial and antifungal applications

Applied Materials Today, Journal Year: 2024, Volume and Issue: 40, P. 102335 - 102335

Published: July 27, 2024

Language: Английский

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Biogenic CuO nanoparticles from Camellia sinensis and Pimpinella anisum plant extracts and their role as antimicrobial agents

Plant Nano Biology, Journal Year: 2025, Volume and Issue: 11, P. 100138 - 100138

Published: Jan. 25, 2025

Language: Английский

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Short and long wavelength laser pulse-dependent physicochemical properties of plasmonic metal nanocomposites: A comparative assessment

Nano-Structures & Nano-Objects, Journal Year: 2025, Volume and Issue: 41, P. 101451 - 101451

Published: Feb. 1, 2025

Language: Английский

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Phytofabrication of copper nanoparticles using Momordica cymbalaria fruit extract and their antibacterial, antioxidant and anti-inflammatory properties

Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100421 - 100421

Published: Feb. 1, 2025

Language: Английский

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The potential of Pteridophyte-derived metal nanoparticles in biomedical research: A comprehensive review

Materials Today Communications, Journal Year: 2025, Volume and Issue: 44, P. 112022 - 112022

Published: Feb. 25, 2025

Language: Английский

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Metal Nanoparticles Obtained by Green Hydrothermal and Solvothermal Synthesis: Characterization, Biopolymer Incorporation, and Antifungal Evaluation Against Pseudocercospora fijiensis

Nanomaterials, Journal Year: 2025, Volume and Issue: 15(5), P. 379 - 379

Published: Feb. 28, 2025

Nanoparticles (NPs) have generated significant interest in various fields due to the unique properties that materials exhibit at nanoscale. This study presents a comparative analysis of copper nanoparticles (Cu-NPs) and cobalt (Co-NPs) synthesized via conventional solvothermal green hydrothermal synthesis using ethylene glycol Medicago sativa extract, respectively. The showed higher efficiency for both Cu-NPs Co-NPs with yields 32.5% 26.7%, Characterization through UV-visible spectroscopy (UV-vis), Fourier-transform infrared (FTIR) atomic force microscopy (AFM) revealed while produced larger particles (76.5 nm Cu-NPs, 86.8 Co-NPs), method yielded smaller (53.8 67.7 Co-NPs) better control over particle size distribution spherical morphology, showing minimal agglomeration. UV-vis confirmed metal oxide formation, FTIR complex patterns NPs (green hydrothermal), indicating plant extract compounds. Antifungal evaluation against Pseudocercospora fijiensis complete inhibition 2000 ppm NP types, no mycelial growth after 30 days. When integrated into chitosan, rougher surfaces, scanning electron microscope (SEM) presence nanocomposites. provides insights an environmentally friendly process their microbiological applications future use organic agriculture.

Language: Английский

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