BioNanoScience, Journal Year: 2024, Volume and Issue: 15(1)
Published: Dec. 10, 2024
Language: Английский
Journal of materials research/Pratt's guide to venture capital sources, Journal Year: 2025, Volume and Issue: unknown
Published: March 10, 2025
Language: Английский
Citations
0
Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)
Published: March 13, 2025
Nanomaterials (NMs), including nanoparticles (NPs), offer promising potential in achieving the European Commission's Green Deal goals of climate-neutral, zero-pollution and circular economy. Metal oxide NPs display antimicrobial properties, with efficacy also towards antimicrobial-resistant bacteria. Nevertheless, increasing manufacture, use unintended release NMs particularly aquatic compartments, raises concerns about their environmental sustainability safety non-target organisms. Within Safe Sustainable by Design framework, this study compares toxicity impacts sonochemically synthesized water-based CuO Zn-doped NPs. Zebrafish embryos were exploited a high-throughput developmental behavioral screening to investigate nanosafety. The Fish Embryo acute Toxicity test was used assess potential, while behaviour addressed tracking activity. Life Cycle Assessment (LCA) methodology implemented through OpenLCA software evaluate footprint synthesis. Our findings showed no significative lethality at tested concentrations (0.01–100 mg/L) (LC50 wCuO > 100 mg/L), exception ZnCuO mg/L = 123 mg/L). Sub-lethality occurred as delayed hatching, partially recovered Zn-doping, embryo development. LCA highlighted dominant role electricity (which represented 47 98% total impacts) copper acetate (37–94%) consumption synthesis, emphasizing importance optimizing energy chemical minimize burden. This research supports safe sustainable design nano-enabled antimicrobials underscores need for an approach comprehensive both risk assessment nanotechnology
Language: Английский
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BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)
Published: March 13, 2025
Language: Английский
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Journal of Chemical Technology & Biotechnology, Journal Year: 2025, Volume and Issue: unknown
Published: March 17, 2025
Abstract BACKGROUND Staphylococcus aureus presents a major public health and food safety challenge due to its ability thrive in various environments. Conventional methods, such as polymerase chain reaction enzyme‐linked immunosorbent assay, often suffer from limitations sensitivity specificity, highlighting the need for innovative detection strategies. RESULTS This study developed novel label‐free aptasensors S. using copper nanoparticles (CuNPs) platform. The CuNPs, characterized by size of 40 nm, spherical morphology, functional stability, served foundation biosensor. An iron‐regulated surface determinant protein A (IsdA)‐binding aptamer, specifically targeting IsdA , was conjugated CuNPs molecular recognition probe, while rhodamine 6G acted signal probe. In absence aptamer kept ‘gate’ on closed, preventing probe release. presence specific binding between pathogen triggered open, releasing generating fluorescence signal. demonstrated linear range (10–10 6 ) CFU mL −1 with limit 1 (correlation coefficient R 2 = 0.947). biosensor high stability reproducibility, ensuring consistent performance. Furthermore, application milk samples highlighted practical utility. CONCLUSION These findings establish CuNP‐based aptasensor promising tool sensitive reliable detection, potential applications monitoring health. © 2025 Society Chemical Industry (SCI).
Language: Английский
Citations
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Journal of Nanotheranostics, Journal Year: 2025, Volume and Issue: 6(2), P. 9 - 9
Published: March 23, 2025
Antibiotic resistance poses a significant global health challenge, undermining the effectiveness of conventional treatments and increasing mortality rates worldwide. Factors such as overuse misuse antibiotics in healthcare agriculture, along with poor infection control practices, have accelerated emergence resistant bacterial strains. The stagnation development new antibiotics, compounded by economic biological challenges, has necessitated alternative approaches to combat infections. Nanotechnology provides promising solution using nanoparticles (NPs), which bacteria through mechanisms like membrane disruption reactive oxygen species (ROS) generation. Metal-based silver zinc oxide possess intrinsic antimicrobial properties, while polymer- carbon-based enhance drug delivery biofilm penetration. Unlike operate multi-mechanistic pathways, reducing likelihood improving treatment efficacy. This review aims provide an updated, in-depth look at recent advances nanoparticle research targeting antibiotic resistance, discussing different types nanoparticles, action, current challenges opportunities. By exploring evolving role nanotechnology addressing this crisis, intends highlight potential for transform landscape infections inspire further into these innovative solutions.
Language: Английский
Citations
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ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(14)
Published: April 1, 2025
Abstract A successful preparation of copper oxide nanoparticles (CuO NPs) by using aqueous leaves extract (PE) plant Combretum roxburghii Spreng. (C. Spreng.) and its application towards oxygen reduction reaction (ORR) are reported here. Aqueous PE was added portion wise into an stirred solution CuSO 4 .5H 2 O at ambient temperature to furnish CuO NPs particles. These prepared were characterized inductively coupled plasma atomic emission spectroscopy (ICP‐AES), Fourier transforms infrared (FTIR), ultraviolet‐visible (UV–vis) spectroscopy, X‑ray diffraction (XRD), scanning electron microscope (SEM), high resolution‐transmission microscopy (HR‐TEM), thermogravimetric analysis (TGA). ICP‐AES SEM mapping established the existence Cu in NPs. The size had been found range 2.06 6.20 nm with distorted spherical shape HR‐TEM. average determined HR‐TEM ∼4.23 nm. Solid residue obtained after evaporating water from is designated as (solid). Both (solid) layered on glassy carbon (GC) electrode form modified electrodes, GC/PE GC/CuO NPs, respectively. electrodes subjected cyclic voltammetry (CV) characterizations. It that displays decent electrocatalytic efficiency for ORR. also exhibits outstanding working constancy (up 1000 CV cycles).
Language: Английский
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Next research., Journal Year: 2025, Volume and Issue: unknown, P. 100356 - 100356
Published: April 1, 2025
Language: Английский
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Environmental Progress & Sustainable Energy, Journal Year: 2025, Volume and Issue: unknown
Published: April 25, 2025
Abstract There are various physical and chemical techniques for the synthesis of nanoparticles. However, green nanoparticles, particularly biosynthesis metal nanoparticles using plants, has garnered significant interest from researchers worldwide. In addition to being an environmentally safe technique, offers numerous biological applications, including antifungal, antiviral, antibacterial, wound healing, antioxidant, antitumor properties. Ephedra (ma‐huang) is a valuable resource phytochemical components that have pharmaceutical effects, such as phenolic compounds, reducing sugars, flavonoids, alkaloids, tannins, saponins. These which possess antimicrobial antioxidant attracted attention stabilizing agents facilitate metallic oxide Various silver, gold, copper, selenium, arsenic, zinc, been synthesized extracts, demonstrating This study aims investigate utilizing different species plant explore their applications.
Language: Английский
Citations
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Advances in bioinformatics and biomedical engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 93 - 102
Published: Feb. 14, 2025
Copper nanoparticles (CuNPs) have garnered significant attention in recent years due to their unique physicochemical properties, including high surface area, quantum effects, and size-dependent optical, electrical, catalytic characteristics. Cu NPs are valued for efficiency oxidation reduction reactions, enhanced by large area. Their cost-effectiveness compared other noble metals like gold silver makes them a viable choice industrial applications. However, challenges such as agglomeration stability remain, necessitating the use of support materials alumina, graphene oxide, titanium dioxide improve durability performance. This review explores synthesis methods NPs, highlights applications water treatment using advanced Cu-based nanoparticles. The synergy between copper various enhances performance offers promising solutions environmental challenges.
Language: Английский
Citations
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Luminescence, Journal Year: 2024, Volume and Issue: 39(10)
Published: Oct. 1, 2024
Abstract The biosynthesis of nanoparticles is a crucial research area aimed at developing innovative, cost‐effective, and eco‐friendly synthesis techniques for various applications. Herein, we synthesized copper oxide (CuNPs) using Couroupita guianensis flower extract via simple green method. These CuNPs demonstrate promising antimicrobial activity anticancer against A549 nonsmall cell lung cancer (NSCLC) cells. We comprehensively characterized the UV spectrum, XRD, FTIR, SEM, EDS analyses. antibacterial anticancerous performance attributed to their spherical‐like morphology, which enhances effective interaction with bacterial Moreover, proved in inactivating Escherichia coli , achieving 2%, 52%, 99% inactivation 0, 30, 60 min, respectively, Listeria monocytogenes 1%, 48%, 98% under visible light. Furthermore, exhibited significant NSCLC cells, viability reductions 10%, 30%, 50%, 70%, 83%, 91% concentrations 25, 50, 100, 150, 200, 250 μg/mL, respectively. potential biomedical
Language: Английский
Citations
1