The Personal Health Applications of Machine Learning Techniques in the Internet of Behaviors

Sustainability, Journal Year: 2023, Volume and Issue: 15(16), P. 12406 - 12406

Published: Aug. 15, 2023

With the swift pace of development artificial intelligence (AI) in diverse spheres, medical and healthcare fields are utilizing machine learning (ML) methodologies numerous inventive ways. ML techniques have outstripped formerly state-of-the-art practices, yielding faster more precise outcomes. Healthcare practitioners increasingly drawn to this technology their initiatives relating Internet Behavior (IoB). This area research scrutinizes rationales, approaches, timing human adoption, encompassing domains Things (IoT), behavioral science, edge analytics. The significance applications based on IoB stems from its ability analyze interpret copious amounts complex data instantly, providing innovative perspectives that can enhance outcomes boost efficiency IoB-based procedures thus aid diagnoses, treatment protocols, clinical decision making. As a result inadequacy thorough inquiry into employment ML-based approaches context using for applications, we conducted study subject matter, introducing novel taxonomy underscores need employ each method distinctively. objective mind, classified cutting-edge solutions challenges five categories, which convolutional neural networks (CNNs), recurrent (RNNs), deep (DNNs), multilayer perceptions (MLPs), hybrid methods. In order delve deeper, systematic literature review (SLR) examined critical factors, such as primary concept, benefits, drawbacks, simulation environment, datasets. Subsequently, highlighted pioneering studies issues. Moreover, several related implementation medicine been tackled, thereby gradually fostering further endeavors health studies. Our findings indicated Tensorflow was most commonly utilized setting, accounting 24% proposed by researchers. Additionally, accuracy deemed be crucial parameter majority papers.

Language: Английский

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The Role of Cytokines in the Pathogenesis of Schizophrenia

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(17), P. 3849 - 3849

Published: Aug. 27, 2021

Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling body evidence implicates immunologic dysfunction as the key element in its pathomechanism. Cytokines, whose altered levels have been increasingly reported various patient populations, are major mediators involved coordination immune system. The available literature reports both elevated proinflammatory well reduced anti-inflammatory cytokines, their effects on clinical status neuroimaging changes. There at least partial genetic basis for association between cytokine alterations schizophrenia. Two other factors implicated development include early childhood trauma disturbances gut microbiome. Moreover, subtypes, characterized by individual symptom severity course, such deficit schizophrenia, seem to differ terms changes peripheral levels. While use systematic review methodology could be difficult due breadth diversity issues covered this review, applied narrative approach allows more holistic presentation. aim was present up-to-date dysregulation effect psychopathological presentation, links with antipsychotic medication. We also attempted summarize postulated underpinnings, including microbiome disturbances, propose trait state markers

Language: Английский

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Psychological stress during childhood and adolescence and its association with inflammation across the lifespan: A critical review and meta-analysis.

Psychological Bulletin, Journal Year: 2022, Volume and Issue: 148(1-2), P. 27 - 66

Published: Jan. 1, 2022

Psychological stress during childhood and adolescence increases risk of health problems across the lifecourse, inflammation is implicated as an underlying mechanism. To evaluate viability this hypothesis, we used meta-analysis to quantify association between childhood/adolescent over lifecourse. Furthermore, addressed three unresolved conceptual questions: (a) Does strength change lifecourse? (b) Are different types stressors differentially associated with inflammation? (c) And which components inflammatory response are involved? A systematic search identified 187 articles reporting 922 associations. Meta-analyses were conducted using a three-level multilevel approach controlled for study quality, conversion confidence, whether effect sizes unadjusted or adjusted (

Language: Английский

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Adverse childhood experiences and severity levels of inflammation and depression from childhood to young adulthood: a longitudinal cohort study

Molecular Psychiatry, Journal Year: 2022, Volume and Issue: 27(4), P. 2255 - 2263

Published: March 3, 2022

Abstract Adverse childhood experiences (ACEs) are associated with depression and systemic inflammation in adults. However, limited longitudinal research has tested these relationships children young people, it is unclear whether an underlying mechanism through which ACEs influence depression. We examined the associations of several across different early-life periods patterns adulthood assessed mediating role inflammation. The data came from Avon Longitudinal Study Parents Children ( N = 3931). prenatal period to adolescence were operationalised using cumulative scores, single adversities, dimensions derived factor analysis. Inflammation (C-reactive protein) was measured on three occasions (9–18 years) depressive symptoms ascertained four (18–23 years). Latent class growth analysis employed delineate group-based trajectories between inflammation/depression multinomial logistic regression Most types all elevated trajectories, larger for threat-related adversities compared other ACEs. Bullying victimisation sexual abuse late childhood/adolescence CRP while unrelated also did not mediate These results suggest that consistently depression, whereas weak people. Interventions targeting this population might offer protection against

Language: Английский

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Immune and Epigenetic Pathways Linking Childhood Adversity and Health Across the Lifespan

Frontiers in Psychology, Journal Year: 2021, Volume and Issue: 12

Published: Nov. 26, 2021

Childhood adversity is associated with a host of mental and physical health problems across the lifespan. Individuals who have experienced childhood (e.g., child abuse neglect, family conflict, poor parent/child relationships, low socioeconomic status or extreme poverty) are at greater risk for morbidity premature mortality than those not exposed to adversity. Several mechanisms likely contribute relationship between lifespan behaviors, cardiovascular reactivity). In this paper, we review large body research within field psychoneuroimmunology, demonstrating early life stress alterations immune system. We first literature that dysregulation different indices, including proinflammatory cytokine production (and its impact on telomere length), illness infection susceptibility, latent herpesvirus reactivation, response tumor. then summarize growing how may alter epigenetic processes. Finally, propose future directions related work basic applied implications.

Language: Английский

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A Scoping Review on Adverse Childhood Experiences Studies Using Latent Class Analysis: Strengths and Challenges

Trauma Violence & Abuse, Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 18, 2023

Adverse childhood experiences (ACEs) studies reveal the profound impacts of experiencing trauma and hardships in childhood. However, cumulative risk approach treating ACEs obscures heterogeneity their consequences, making actionable interventions impossible. latent class analysis (LCA) has increasingly been used to address these concerns by identifying underlying subgroups people who experience distinctive patterns co-occurring ACEs. Though LCA its strengths, existing research produces few comparable findings because results are dependent on measures indicators, which vary widely study. Therefore, a scoping review using that focuses measures, is needed inform field. Following Arksey O'Malley's five-stage methodological framework, we first identified 211 articles from databases EBSCOhost, PubMed, Scopus "adverse experiences" for title search "latent analysis" abstract search. Based inclusion criteria peer-reviewed written English published 2012 2022 exclusion nonempirical not analyzing ACEs, finally selected 58 this review. Results showed endorsed community examine associations between human health well-being across culturally diverse populations. overcame limitations traditional methods revealing specific clusters exert potent effects certain outcomes. arbitrary nature selecting limited use theory impedes field moving forward.

Language: Английский

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Factors Associated with the Development of Depression and the Influence of Obesity on Depressive Disorders: A Narrative Review

Biomedicines, Journal Year: 2024, Volume and Issue: 12(9), P. 1994 - 1994

Published: Sept. 2, 2024

Depression affects several aspects of life, including socioeconomic status, relationships, behavior, emotions, and overall health. The etiology depression is complex influenced by various factors, with obesity emerging as a significant contributor. This narrative review aims to investigate the factors associated development depression, particular focus on role obesity. literature search was conducted PubMed, Embase, PsycINFO from May July 2024. highlights impact environmental conditions; lifestyle choices, physical activity dietary habits; stress; traumatic experiences; neurotransmitter imbalances; medical psychological hormone fluctuations; epigenetic depression. A key emphasis placed inflammatory processes linked obesity, which may drive bidirectional relationship between findings suggest that an increased risk potentially due chronic inflammation, neurochemical dysregulation, emotional social challenges related weight stigma management. Understanding these interconnected important for developing targeted interventions address both leading improved quality life those affected.

Language: Английский

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Elevated risk for psychiatric outcomes in pediatric patients with Multisystem Inflammatory Syndrome (MIS-C): A review of neuroinflammatory and psychosocial stressors

Brain Behavior & Immunity - Health, Journal Year: 2024, Volume and Issue: 38, P. 100760 - 100760

Published: March 18, 2024

Multisystem Inflammatory Syndrome in Children (MIS-C) is a secondary immune manifestation of COVID-19 involving multiple organ systems the body, resulting fever, skin rash, abdominal pain, nausea, shock, and cardiac dysfunction that often lead to hospitalization. Although many these symptoms resolve following anti-inflammatory treatment, long-term neurological psychiatric sequelae MIS-C are unknown. In this review, we will summarize two domains disease course, 1) Neuroinflammation brain 2) Psychosocial disruptions from stress both domains, present existing clinical findings hypothesize potential connections outcomes. This first review conceptualize holistic framework risk patients includes neuroinflammatory psychosocial factors. As cases severe subside, it important for clinicians monitor outcomes vulnerable patient population.

Language: Английский

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Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 23, 2025

Abstract Maternal adverse childhood experiences (ACEs) are linked to negative health and developmental outcomes in offspring. However, whether maternal ACEs influence infant weight gain the first months of life, if this effect differs by sex, remains unclear. This study included 352 full-term newborns from low-risk pregnancies their mothers low-income settings Brazil. Anthropometric data (weight, length, head circumference) other information (feeding type, offspring family income) were collected at delivery (W0), discharge (W1), up 8 weeks postpartum (W2). assessed using CDC-Kaiser Questionnaire, was calculated as difference between W2 W1, divided number days measurements. The association positive only male (unstandardized coefficient (male) = 1.82, SE 0.438, p < 0.001); for each 1-point increase score (e.g., 0 1), increased 1.8 g/day. These findings indicate that associated with infants during two potentially increasing risk future obesity. Further research is required investigate underlying biological mechanisms neurodevelopmental implications.

Language: Английский

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Adverse childhood experiences and adolescent cannabis use trajectories: findings from a longitudinal UK birth cohort

The Lancet Public Health, Journal Year: 2023, Volume and Issue: 8(6), P. e442 - e452

Published: May 25, 2023

BackgroundAdverse childhood experiences (ACEs) are classically defined as physical abuse, sexual emotional neglect, bullying, parental substance use or violence between parents, mental health problems suicide, separation, a parent convicted of criminal offence. Exposure to ACEs can be associated with cannabis use, but no comparisons across all adversities have been made while also considering timing and frequency use. We aimed explore the association in adolescence, cumulative number individual ACEs.MethodsWe used data from Avon Longitudinal Study Parents Children, longitudinal UK birth cohort study. latent classes were derived self-reported at multiple timepoints participants aged 13–24 years. ages 0 years 12 prospective retrospective reports by parents participant. Multinomial regression was analyse effect both exposure ten on outcomes.Findings5212 (3132 [60·0%] female 2080 [40·0%] male; 5044 [96·0%] White 168 [4·0%] Black, Asian, minority ethnic) included this After adjustment for polygenic risk environmental factors, who had 4 more age 0–12 increased early persisting regular (relative ratio [RRR] 3·15 [95% CI 1·81–5·50]), later onset (1·99 [1·14–3·74]), occasional (2·55 [1·74–3·73]) compared low adjustment, abuse (RRR 3·90 2·10–7·24]), (2·02 [1·26–3·24]), (2·27 [1·31–3·98]), (2·44 [1·49–3·99]), separation (1·88 [1·08–3·27]) use.InterpretationRisks problematic adolescent highest individuals reporting ACEs, particularly raised those abuse. Public measures address might reduce use.FundingThe Wellcome Trust, Medical Research Council, Alcohol UK.

Language: Английский

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