Measurement of New Biomarkers of Immunity and Welfare in Colostrum and Milk of Pigs: Analytical Validation and Changes during Lactation DOI Creative Commons
María Botia, Damián Escribano, Eva Mainau

et al.

Biology, Journal Year: 2024, Volume and Issue: 13(10), P. 829 - 829

Published: Oct. 16, 2024

Colostrum is a mammary secretion released from the time of farrowing to 36 h post-farrowing. After this and during all rest lactation, considered milk. The objectives study were: (1) perform an analytical validation in colostrum milk sows assays for four analytes related immunity: total ADA (tADA) its isoenzymes (ADA1 ADA2), myeloperoxidase (Mpx), calprotectin, calgranulin, two welfare: cortisol alpha-amylase. (2) To evaluate changes these lactation (3) assess correlations between new analytes, as well with IgG IgA. In validation, were precise accurate. When evaluated, concentration tADA ADA2 was found be higher than (p < 0.02), while activity Mpx observed mature 0.03). Furthermore, alpha-amylase compared 0.04 p 0.0001, respectively). Regarding relation showed significant correlation both IgA calprotectin correlated calgranulin Mpx. Further studies should performed elucidate possible practical application evaluated biomarkers sows.

Language: Английский

Bioactive Components of Human Milk and Their Impact on Child’s Health and Development, Literature Review DOI Open Access
Hubert Szyller, Katarzyna Antosz, Joanna Batko

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(10), P. 1487 - 1487

Published: May 14, 2024

The composition of human breast milk is an ideal combination substances necessary for the healthy development infant’s body while protecting from pathogens and balanced microbiota. Its dynamic changes with age child, meeting their current needs. study provides a thorough overview components, such as immunological growth factors, hormones, carbohydrates, lipids, minerals, vitamins. Authors focus on capturing most important aspects effects these newborn’s body, also looking specific connections describing given systems. Supplementation use ingredients are discussed. purpose this paper to present state knowledge about bioactive components impact growth, development, health young child.

Language: Английский

Citations

11
Maternal Childhood Trauma and Offspring Hypothalamic–Pituitary–Adrenal Axis Function from Infancy to 6 Years of Age DOI Creative Commons
Lisa Loheide‐Niesmann, Roseriet Beijers, Carolina de Weerth

et al.

Developmental Psychobiology, Journal Year: 2025, Volume and Issue: 67(2)

Published: Feb. 17, 2025

ABSTRACT Childhood trauma experiences can carry over to the next generation, affecting health and behavior of survivors’ children. However, mechanisms underlying these intergenerational effects childhood are not yet clear. One mechanism may be changes in children's hypothalamic–pituitary–adrenal (HPA) axis. This preregistered longitudinal study examined associations between 170 mothers’ (maltreatment, family peer violence) their cortisol reactivity total circadian output at 12 months 6 years age. Multilevel regression analyses revealed that maternal was significantly associated with child or output, neither nor Thus, we found no evidence this community sample impacts young HPA axis functioning. Exploratory moderation prenatal psychopathology slope: mothers high slope, positively while association negative low slope. Future research should replicate findings older children more severely trauma‐exposed populations further explore moderators association.

Language: Английский

Citations

0
From Mind to Milk: The Influence of Psychological Factors on the Composition of Human Breast Milk DOI Open Access

Krystian Skowron,

Igor Lichocki,

Filip Godziszewski

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(6), P. 1093 - 1093

Published: March 20, 2025

Background/Objectives: Breast milk is a complex fluid crucial for infant development, nutrition, and immunological neurodevelopmental support. Recent findings suggest that factors regarding mental health, such as stress, anxiety, postpartum depression (PPD), may influence the composition of breast milk. This review aims to synthesize current knowledge relationship between mother’s state biochemical profile human milk, focusing mainly on nutrients, hormones, immune factors, microbiota. Methods: A systematic literature search was conducted in PubMed Web Science using predefined keywords related psychological composition. Studies involving validated assessment tools only subjects were included, accordance with PRISMA guidelines. Results: Findings indicated maternal stress PPD are associated alterations Elevated cortisol changes melatonin prolactin levels have been observed. Immune components, secretory immunoglobulin transforming growth factor beta 2, exhibit variable responses depending type duration. Lower concentrations docosahexaenoic acid polyunsaturated fatty observed among mothers diagnosed depression. Additionally, distress infants’ gut microbiota composition, potentially affecting long-term health outcomes. Conclusions: The plays an essential role shaping Understanding these associations highlights need support during period optimize development. Future research should focus molecular mechanisms underlying potential interventions mitigate adverse effects.

Language: Английский

Citations

0
Postpartum symptoms of anxiety, depression and stress: differential relationships to women’s cortisol profiles DOI Creative Commons
Sandra J. Weiss, Ling Xu

Archives of Women s Mental Health, Journal Year: 2024, Volume and Issue: 27(3), P. 435 - 445

Published: Jan. 12, 2024

Abstract Purpose Women are at high risk of stress, anxiety, and depression during the postpartum but ways in which these different types psychological distress related to cortisol regulation is not clear. We examined distinct association each type with women’s average level, awakening response (CAR), decline across day (diurnal slope), overall amount secretion (AUC G ). Methods At 6 months postpartum, a diverse group 58 women completed measures depression, perceived life stressors. Each woman provided 4 salivary samples for assay from waking bedtime on 2 consecutive days. Linear regressions were used examine associations anxiety measures, controlling number stressful events. Results Depressive symptoms associated less rise CAR (β = -.46, p 0.01), steeper diurnal slope .51, 0.006), higher level .42, .01). who met clinical cutoff an disorder had lower output -.29, 0.03). Stress was any metric. Conclusions Findings suggest that stress alterations than more severe distress. Anxiety may have opposite profiles dysregulation. indicate mental health assessment critical even later so interventions can be initiated reduce emotional suffering impaired regulation.

Language: Английский

Citations

3
Impact of Maternal Health and Stress on Steroid Hormone Profiles in Human Milk: Implications for Infant Development DOI Creative Commons
Isabel Ten-Doménech, Alba Moreno-Giménez,

Laura Campos-Berga

et al.

Journal of Lipid Research, Journal Year: 2024, Volume and Issue: unknown, P. 100688 - 100688

Published: Oct. 1, 2024

Language: Английский

Citations

1
Measurement of New Biomarkers of Immunity and Welfare in Colostrum and Milk of Pigs: Analytical Validation and Changes during Lactation DOI Creative Commons
María Botia, Damián Escribano, Eva Mainau

et al.

Biology, Journal Year: 2024, Volume and Issue: 13(10), P. 829 - 829

Published: Oct. 16, 2024

Colostrum is a mammary secretion released from the time of farrowing to 36 h post-farrowing. After this and during all rest lactation, considered milk. The objectives study were: (1) perform an analytical validation in colostrum milk sows assays for four analytes related immunity: total ADA (tADA) its isoenzymes (ADA1 ADA2), myeloperoxidase (Mpx), calprotectin, calgranulin, two welfare: cortisol alpha-amylase. (2) To evaluate changes these lactation (3) assess correlations between new analytes, as well with IgG IgA. In validation, were precise accurate. When evaluated, concentration tADA ADA2 was found be higher than (p < 0.02), while activity Mpx observed mature 0.03). Furthermore, alpha-amylase compared 0.04 p 0.0001, respectively). Regarding relation showed significant correlation both IgA calprotectin correlated calgranulin Mpx. Further studies should performed elucidate possible practical application evaluated biomarkers sows.

Language: Английский

Citations

0