Attitudes and Barriers of Polish Women towards Breastfeeding—Descriptive Cross-Sectional On-Line Survey DOI Open Access
Agnieszka Kolmaga, Katarzyna Dems-Rudnicka, Anna Garus-Pakowska

et al.

Healthcare, Journal Year: 2024, Volume and Issue: 12(17), P. 1744 - 1744

Published: Sept. 2, 2024

Background: Breastfeeding is the gold standard in infant nutrition. Successful breastfeeding depends on many factors, including help of medical personnel teaching breastfeeding, need for professional work, and breastfeeding-friendly places public spaces. The main goal was to identify various barriers among mothers breastfeeding. Methods: This study used a quantitative descriptive research design. We recruited 419 aged at least 18 years old through social media. Results were analysed using Pearson’s chi-squared Fisher’s tests independence pairs dependent independent variables. Results: Most often, women gave birth age 25–30, had one or two children, attended higher education. Almost half them lived large city child by caesarean section. A total 83.1% planned breastfeed, but not all able do so reasons. One-third felt sorry themselves that they change their feeding method. majority did receive sufficient hospital terms learning how breastfeed (61%), use lactation consultant (67%), answered there no place residence (65%). Only 43.2% returned work without ceasing 42% experienced feelings embarrassment when place. most frequently indicated barrier lack suitable location where woman would feel comfortable, calm, intimate. Conclusion: There are towards breastfeeding: too few consultants, problems with mother wants return unfriendly Efforts must be made support

Language: Английский

Determination of heavy metal levels and potential health risk of raw cow milk in the Iraqi Kurdistan Region DOI
Hiwa Mohammad Qadr, Najeba F. Salih, Murtadha Sh. Aswood

et al.

International Journal of Environmental & Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12

Published: Feb. 25, 2025

Language: Английский

Citations

2
Bioactive compounds in human milk DOI
Anthony E. Castro, Maria Sanchez-Holgado, Miguel Sáenz de Pipaón

et al.

Current Opinion in Clinical Nutrition & Metabolic Care, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 12, 2025

Purpose of review: Human milk is the optimal food choice for infants. Reviewing latest advances in research about human compounds and their effect on health helps understand benefits breastfeeding improves knowledge key bioactive nutrients that can be used to improve feeding during infancy, with short long-time effects health. Recent findings: In last years, it has been described how such as oligosaccharides, hormones, lipids, cellular components microbes play an important role infants’ health, reducing risk infectious, metabolic autoimmune diseases. The mechanisms transmission from mother infant these are not always well described, but there several lines biological beneficial effects. Summary: These findings may help maternal interventions, modifiable factors able modulate composition. They development formulas enhance nutritional plans. Also, identification isolation describe new ways supplementation.

Language: Английский

Citations

0
Challenges and Opportunities in Quantifying Bioactive Compounds in Human Breastmilk DOI Creative Commons
Amna Ghith, Reza Maleki, Luke E. Grzeskowiak

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(3), P. 325 - 325

Published: Feb. 24, 2025

Breastmilk is a complex biological fluid containing over thousand bioactive proteins, lipids, cells and small molecules that provide nutrition immunological protection for infants children. The composition of breastmilk unique to each individual can also vary within individuals according breastfeeding duration, maternal health, time day, other factors. As such, the be considered “fingerprint” could interrogated identify biomarkers breast health disease. However, accurate quantification components in remains significant challenge. Approaches such as immunoassays mass spectrometry have been largely applied study blood or fluids require validation optimisation before these techniques used accurately quantify compounds breastmilk. Development protocols specific should carried out with high precision, confidence, sensitivity. This review explores challenges opportunities associated different components.

Language: Английский

Citations

0
Human milk oligosaccharide secretion dynamics during breastfeeding and its antimicrobial role: A systematic review DOI
Mohammed Al‐Beltagi

World Journal of Clinical Pediatrics, Journal Year: 2025, Volume and Issue: 14(2)

Published: March 18, 2025

BACKGROUND Human milk oligosaccharides (HMOs) are bioactive components of breast with diverse health benefits, including shaping the gut microbiota, modulating immune system, and protecting against infections. HMOs exhibit dynamic secretion patterns during lactation, influenced by maternal genetics environmental factors. Their direct indirect antimicrobial properties have garnered significant research interest. However, a comprehensive understanding dynamics their correlation efficacy remains underexplored. AIM To synthesize current evidence on lactation evaluate roles bacterial, viral, protozoal pathogens. METHODS A systematic search PubMed, Scopus, Web Science, Cochrane Library focused studies investigating natural synthetic HMOs, dynamics, properties. Studies involving human, animal, in vitro models were included. Data HMO composition, temporal patterns, mechanisms action extracted. Quality assessment was performed using validated tools appropriate for study design. RESULTS total 44 included, encompassing research. exhibited 2′-fucosyllactose (2′-FL) lacto-N-tetraose peaking early declining over time, while 3-fucosyllactose (3-FL) increased later stages. demonstrated through pathogen adhesion inhibition, biofilm disruption, enzymatic activity impairment. Synthetic bioengineered 2′-FL 3-FL, structurally functionally comparable to effectively inhibiting pathogens such as Pseudomonas aeruginosa , Escherichia coli Campylobacter jejuni . Additionally, synergistic effects antibiotics, enhancing resistant CONCLUSION vital defense, supporting infant targeting various Both hold potential therapeutic applications, particularly nutrition adjuncts antibiotics. Further research, clinical trials, is essential address gaps knowledge, validate findings, explore broader applicability improving neonatal health.

Language: Английский

Citations

0
The fifty billion dollar question: does formula cause necrotizing enterocolitis? DOI Creative Commons
Mark A. Underwood

Journal of Perinatology, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Abstract The question of whether preterm infant formulas cause necrotizing enterocolitis (NEC) is the subject multiple lawsuits and has daily relevance in care infants. Research supporting hypothesis that toxic components formula NEC limited to preclinical data while from human infants are lacking. Human milk should be first choice for most infants, however, at times a critical alternative. It absence increases risk rather than formula.

Language: Английский

Citations

0
Breastfeeding: The Multifaceted Impact on Child Development and Maternal Well-Being DOI Open Access
Aleksandra Purkiewicz, Kamila J. Regin,

Wajeeha Mumtaz

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(8), P. 1326 - 1326

Published: April 11, 2025

Breastfeeding is recognized as the gold standard in infant nutrition, providing necessary nutrients for optimal growth and development. Beyond its nutritional function, breastfeeding has numerous benefits both mother child. This literature review examines effects of on development nervous immune systems, influence cognitive development, impact stress lactation. In addition, it explores emotional mothers, challenges associated with exclusive breastfeeding, process weaning along implications infant. It indicated that significantly affects lactation regulation, elevated cortisol levels potentially disrupting hormonal balance. Furthermore, essential roles oxytocin, sialic acid, docosahexaenoic acid brain functions are highlighted. regulation baby’s sleep through tryptophan, serotonin, melatonin, which at same time provide baby a sense security mother. women who breastfeed less likely to suffer from mental health problems lower risk hypertension, diabetes, cardiovascular disease. The often difficult child; thus, should be introduced gradually minimize stress, anxiety, potential mood disturbances

Language: Английский

Citations

0
The Associations of Maternal Pre-pregnancy Body Mass Index with Human Milk Fatty Acid and Phospholipid Composition in the Observational Norwegian Human Milk Study. DOI

Talat Bashir Ahmed,

Merete Eggesbø,

Rachel Criswell

et al.

Journal of Nutrition, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
A newborn's perspective on immune responses to food DOI Creative Commons
Valérie Verhasselt

Immunological Reviews, Journal Year: 2024, Volume and Issue: 326(1), P. 117 - 129

Published: Aug. 20, 2024

Summary In this review, we will highlight infants' immune responses to food, emphasizing the unique aspects of early‐life immunity and critical role breast milk as a food dedicated infants. Infants are susceptible inflammatory rather than tolerance at mucosal skin barriers, necessitating strategies promote oral that consider susceptibility. Breast provides nutrients for growth cell metabolism, including cells. The content milk, influenced by maternal genetics environmental exposures, prepares infant's system outside world, solid foods. To do this, promotes development through antigen‐specific non‐antigen‐specific education exposing newborn respiratory allergens acting on three key targets allergy prevention: gut microbiota, epithelial cells, Building knowledge how exposome human composition influence offspring's healthy lead recommendations meet specific needs developing increase chances promoting an appropriate response in long term.

Language: Английский

Citations

3
Breastfeeding and infant gut microbiota: influence of bioactive components DOI Creative Commons
Dongqing Xu, Fengyi Wan

Gut Microbes, Journal Year: 2024, Volume and Issue: 17(1)

Published: Dec. 27, 2024

Establishment of the gut microbiota during infancy is critical for host health with long-lasting implications. In this orchestrated process, microbial assembly influenced by an increasing number genetic and environmental factors, among which breastfeeding considered as one most significant drivers infant development. As optimal diet infants, maternal milk provides numerous nutritional, microbial, bioactive components to ensure adequate growth development a 'healthy' early life. This review will summarize available evidence, particularly recent progress, on how various compounds supplied in affect establishment early-life promote further interest investigation important area.

Language: Английский

Citations

2
Per Os to Protection – Targeting the Oral Route to Enhance Immune-mediated Protection from Disease of the Human Newborn DOI Creative Commons
Valérie Verhasselt, Arnaud Marchant, Tobias R. Kollmann

et al.

Journal of Molecular Biology, Journal Year: 2024, Volume and Issue: 436(19), P. 168718 - 168718

Published: July 31, 2024

Insight into the mechanisms that guide host immune response towards either immunogenicity or tolerance is crucial for success of many biomedical interventions, including vaccination

Language: Английский

Citations

2