Influence of Body Mass Index (BMI) and Waist–Hip Ratio (WHR) on Selected Semen Parameters DOI Open Access
Kamil Gill, Monika Frączek, Maciej Kurpisz

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(9), P. 4089 - 4089

Published: April 25, 2025

Because male obesity may result in reproductive failure, we aimed to examine the possible links among body mass index (BMI), waist–hip ratio (WHR), and basic semen parameters, oxidation–reduction potential of semen, total antioxidant capacity seminal plasma, ability sperm bind hyaluronic acid, DNA fragmentation (SDF). This study was performed on (n = 543) collected from volunteers classified as follows: normal weight (BMI 18.5–24.9 kg/m2), overweight 25.0–29.9 obese ≥ 30.0 with a WHR (<1) or abnormal (≥1). No significant differences standard parameters were found between men BMI those overweight/obesity. However, compared men, had higher SDF prevalence risk for an > 20%. Compared < 1, 1 significantly lower motility, morphology, vitality increased index, In conclusion, greater negative impact conventional than BMI. Both negatively influenced chromatin integrity only. Obesity is factor damage.

Language: Английский

The Oxidative Stress of Human Sperm Cryopreservation DOI Creative Commons
Steven D. Fleming,

Laura Kelly Thomson

Antioxidants, Journal Year: 2025, Volume and Issue: 14(4), P. 402 - 402

Published: March 28, 2025

Due to their negligible cytoplasm and composition of the sperm plasmalemma, spermatozoa are particularly vulnerable lipid peroxidative damage induced by reactive oxygen species (ROS). Most ROS referred as free radicals because they have unpaired electrons, causing them scavenge electrons from atoms within tissues, resulting in oxidative cellular components including cell membranes, intracellular organelles, DNA. The potential consequences stress include impaired function, DNA fragmentation, apoptosis. Understanding mechanisms that mediate during cryopreservation is key development improved freezing media formulations methodology mitigate its occurrence. Historically, elucidation those has proven largely elusive complicated positive role also play messengers redox signaling different pathways More recently, been revealed most likely suspect cryopreservation-induced damage. This narrative review was intended provide an in-depth analysis involved offer insight into possible improvements cryopreservation.

Language: Английский

Citations

0
Influence of Body Mass Index (BMI) and Waist–Hip Ratio (WHR) on Selected Semen Parameters DOI Open Access
Kamil Gill, Monika Frączek, Maciej Kurpisz

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(9), P. 4089 - 4089

Published: April 25, 2025

Because male obesity may result in reproductive failure, we aimed to examine the possible links among body mass index (BMI), waist–hip ratio (WHR), and basic semen parameters, oxidation–reduction potential of semen, total antioxidant capacity seminal plasma, ability sperm bind hyaluronic acid, DNA fragmentation (SDF). This study was performed on (n = 543) collected from volunteers classified as follows: normal weight (BMI 18.5–24.9 kg/m2), overweight 25.0–29.9 obese ≥ 30.0 with a WHR (<1) or abnormal (≥1). No significant differences standard parameters were found between men BMI those overweight/obesity. However, compared men, had higher SDF prevalence risk for an > 20%. Compared < 1, 1 significantly lower motility, morphology, vitality increased index, In conclusion, greater negative impact conventional than BMI. Both negatively influenced chromatin integrity only. Obesity is factor damage.

Language: Английский

Citations

0