Untargeted Metabolomics Comparison and Nutrition Evaluation of Geographical Indication Newhall Navel Oranges in China

Foods, Journal Year: 2025, Volume and Issue: 14(3), P. 355 - 355

Published: Jan. 22, 2025

The untargeted metabolomics of Newhall navel oranges from three areas in China—Ganzhou, Fengjie, and Zigui—with geographical indication (GI) was measured using LC-MS/MS. Orthogonal partial least squares discriminant analysis performed for sample classification important metabolite identification. This approach identified the best markers origin able to discriminate Ganzhou, Zigui orange samples. For peeled samples, 2-isopropylmalic acid, succinic citric L-aspartic L-glutamic γ-semialdehyde, D-β-phenylalanine, hesperetin, hydrocinnamic 4-hydroxycinnamic dehydroascorbate were used origin. All these overexpressed samples area, followed by Ganzhou area. As unpeeled isovitexin 2′-O-β-D-glucoside, isovitexin, diosmetin, trans-2-hydroxycinnamate trans-cinnamate, β-carotene their first seven Zigui-planted whole showed highest levels, last richest Ganzhou-planted According variation discriminating origins or with GI value titratable acidity those Zigui, planted have balance between taste nutrition. work confirms that combined OPLS-DA is an effective way tracing overall quality evaluation.

Language: Английский

---

Extended recommendations on the nomenclature for microbial catabolites of dietary (poly)phenols, with a focus on isomers

Food & Function, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

There is an increasing body of evidence indicating that phenolic compounds derived from microbiota-mediated breakdown dietary (poly)phenolics in the colon are at least partially responsible for beneficial effects a plant-based diet.

Language: Английский

---

Enhanced health benefits of Psidium guajava peel fermented with Lactiplantibacillus from Myeolchi-jeot: Antioxidant, anti-inflammatory, and anti-cancer properties

Food Bioscience, Journal Year: 2024, Volume and Issue: 59, P. 104211 - 104211

Published: April 26, 2024

Language: Английский

---

Metabolic profiling of (poly)phenolic compounds in mouse urine following consumption of hull-less and purple-grain barley

Food & Function, Journal Year: 2024, Volume and Issue: 15(16), P. 8300 - 8309

Published: Jan. 1, 2024

This study proposes for the first time characterization and metabolic pathways of (poly)phenolic compounds generated after sustained intake hull-less purple-grain barley in vivo .

Language: Английский

---

A critical examination of human data for the biological activity of phenolic acids and their phase-2 conjugates derived from dietary (poly)phenols, phenylalanine, tyrosine and catecholamines

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 60

Published: Oct. 9, 2024

Free or conjugated aromatic/phenolic acids arise from the diet, endogenous metabolism of catecholamines (adrenaline, noradrenaline, dopamine), protein (phenylalanine, tyrosine), pharmaceuticals (aspirin, metaprolol) plus gut microbiota dietary (poly)phenols and undigested protein. Quantitative data obtained with authentic calibrants for 112 including phase-2 conjugates in human plasma, urine, ileal fluid, feces tissues have been collated mean/median values compared

Language: Английский

---

Chronic consumption of a bergamot-based beverage does not affect glucose, lipid and inflammatory biomarkers of cardiometabolic risk in healthy subjects: a randomised controlled intervention study

Food & Function, Journal Year: 2024, Volume and Issue: 15(11), P. 5842 - 5854

Published: Jan. 1, 2024

Background: Pure bergamot juice exerts lipid lowering effects in dyslipidemic subjects. It is unknown whether bergamot-based beverages exert similar healthy Aim: To assess the effects, if any, of a beverage (BBB, ≤25%) on lipid, metabolic and inflammatory biomarkers. Methods: Forty-five subjects were randomised 1 : to BBB intake (400 mL day-1) (55.5%) or control (44.5%) for 12 weeks. Anthropometric (waist circumference, body mass index (BMI)) clinical (blood pressure) parameters, blood samples (glucose, glycated haemoglobin, insulinemia, profile, liver renal function, biomarkers) 24-h urine analysis (poly)phenol metabolites collected at baseline Intakes energy, nutrients food groups assessed by 7-day dietary record. Results: Both exhibited time-related significant decrease total cholesterol (p = 0.02), fasting plasma glucose 0.016), insulin 0.034), BMI < 0.001) waist circumference 0.04), but with no between-arm difference. The urinary profile from BBB-derived (poly)phenols well discriminated two study groups, documenting good compliance intervention arm. Notably, 3-hydroxy-3-methylglutaryl (HMG) -containing flavanones derived HMG-containing not detectable. was tolerated adverse events recorded. Conclusion: This first randomized controlled trial consumption showed cardiometabolic risk profile. safe nutritional adjunct context balanced diet.

Language: Английский

---

Bioavailability of Mango (Poly)Phenols: An Evaluation of the Impact of the Colon, and Phenylalanine and Tyrosine on the Production of Phenolic Catabolites

Published: Jan. 1, 2024

Language: Английский

---

Phytonutrient Formulation Using Gum Arabic and Adansonia Digitata Pulp: Lessons for Boosting the Human Immune System - Part 1

Phytomedicine Plus, Journal Year: 2024, Volume and Issue: unknown, P. 100663 - 100663

Published: Oct. 1, 2024

Language: Английский

---

Using Targeted Metabolomics to Unravel Phenolic Metabolites of Plant Origin in Animal Milk

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(8), P. 4536 - 4536

Published: April 20, 2024

Milk holds a high nutritional value and is associated with diverse health benefits. The understanding of its composition (poly)phenolic metabolites limited, which necessitates comprehensive evaluation the subject. This study aimed at analyzing profile commercial milk samples from cows goats investigating their sterilization treatments, fat content, lactose content. Fingerprinting phenolic was achieved by using ultra-high-performance liquid chromatography coupled triple-quadrupole mass spectrometry (UHPLC-QqQ-MS/MS). Two hundred three potential microbial phase II main dietary (poly)phenols were targeted. Twenty-five identified, revealing array in milk, including isoflavones catabolites equol O-desmethylangolensin, phenyl-γ-valerolactones (flavan-3-ol catabolites), enterolignans, urolithins (ellagitannin benzene diols, hippuric acid derivates. Goat's contained higher concentrations these than cow's while process (fat content) had minimal impact on metabolite profiles. Thus, consumption goat's might serve as means to supplement bioactive metabolites, especially individuals limited production capacity. However, further research needed elucidate effects milk-derived phenolics.

Language: Английский

---

Bioavailability of mango (poly)phenols: an evaluation of the impact of the colon, and phenylalanine and tyrosine on the production of phenolic catabolites

Free Radical Biology and Medicine, Journal Year: 2024, Volume and Issue: 225, P. 605 - 616

Published: Oct. 18, 2024

Language: Английский

---