Chemosphere,
Journal Year:
2025,
Volume and Issue:
377, P. 144315 - 144315
Published: March 28, 2025
Understanding
the
impact
of
endocrine
disruptor
compounds
(EDCs)
across
a
wide
range
species
is
crucial,
given
their
ubiquitous
presence.
Although
invertebrate
lack
sex
steroid
hormone
pathways,
they
exhibit
sensitivity
to
EDCs,
which
could
affect
population
dynamics.
This
study
assessed
reproductive
endpoints
and
oxidative
stress
parameters
in
Eisenia
fetida
following
exposure
estradiol
soy
isoflavones,
resembling
concentrations
found
livestock
manure.
The
experiment
used
artificial
soil,
as
recommended
by
OECD
guidelines
(7:2:1
sand,
kaolin
peat).
Adult
specimens
were
randomly
divided
into
seven
groups
(n
=
11/replicate):
one
control,
three
(156.1,
283.4
633.8
μg/kg
dry
soil)
isoflavones
(113.0,
215.3
405.0
mg/kg
concentrations.
After
eight
weeks,
samples
collected
for
cytological,
histological
biochemical
analysis.
Offspring
development
was
after
12
additional
weeks.
Higher
isoflavone
led
lower
germ
cell
number
increased
abnormalities,
especially
seminal
vesicles
ovaries.
Catalase
peroxidase
activities
significantly
all
treated
groups.
did
not
E.
offspring.
These
findings
highlight
fetida's
EDCs
at
tissue
level,
suggesting
its
use
bioindicator
assessing
EDC
contamination
soils.
Disciplinarum Scientia. Série Ciências Naturais e Tecnológicas,
Journal Year:
2025,
Volume and Issue:
26(1), P. 45 - 63
Published: Jan. 1, 2025
Population
growth
drives
food
industries
to
seek
large-scale
production
technologies,
often
involving
organic
compounds
that
can
negatively
impact
the
environment.
One
example
is
17α-methyltestosterone
(17MT),
a
hormone
used
masculinize
Nile
tilapia,
genetically
changing
females
phenotypically
males.
Endocrine
disruptors
such
as
17MT
cause
harm
health,
affecting
and
reproduction
of
organisms,
persist
in
environment
leading
compromise
chains
due
bioaccumulation.
Different
techniques
for
quantifying
removing
17MT,
advanced
oxidative
processes,
nanofiltration
systems
wetlands,
have
been
developed
order
minimize
impacts
on
environment,
biota
human
beings,
search
balance
productivity
sustainability.
The
objective
this
work
was
carry
out
bibliographical
research
endocrine
disruptor
including
characterization,
its
occurrence
possible
effects
health.
Phytotherapy Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 24, 2025
ABSTRACT
The
human
body
gets
exposed
to
a
variety
of
toxins
intentionally
or
unintentionally
on
regular
basis
from
sources
such
as
air,
water,
food,
and
soil.
Certain
can
be
synthetic,
while
some
are
biological.
affect
the
various
parts
by
activating
numerous
pro‐inflammatory
markers,
like
oxidative
stresses,
that
tend
disturb
normal
function
organs
ultimately.
Nowadays,
people
use
different
types
herbal
treatments,
viz.,
drinks
contain
spices
for
detoxification
their
bodies.
One
example
is
turmeric,
most
commonly
available
spice
in
kitchen
used
across
all
kinds
households.
Turmeric
contains
curcumin,
which
natural
polyphenol.
Curcumin
medicinal
compound
with
biological
activities,
antioxidant,
antineoplastic,
anti‐inflammatory,
antibacterial.
Hence,
this
review
gives
comprehensive
insight
into
promising
potential
curcumin
heavy
metals,
carbon
tetrachloride,
drugs,
alcohol,
acrylamide,
mycotoxins,
nicotine,
plastics.
encompasses
diverse
animal‐based
studies
portraying
curcumin's
role
nullifying
toxic
effects
(especially
liver,
kidney,
testicles,
brain)
enhancing
defensive
signaling
pathways,
improving
antioxidant
enzyme
levels,
inhibiting
markers
activities
so
on.
Furthermore,
also
argues
over
safety
assessment
its
utilization
detoxifying
agent.
Chemosphere,
Journal Year:
2025,
Volume and Issue:
377, P. 144315 - 144315
Published: March 28, 2025
Understanding
the
impact
of
endocrine
disruptor
compounds
(EDCs)
across
a
wide
range
species
is
crucial,
given
their
ubiquitous
presence.
Although
invertebrate
lack
sex
steroid
hormone
pathways,
they
exhibit
sensitivity
to
EDCs,
which
could
affect
population
dynamics.
This
study
assessed
reproductive
endpoints
and
oxidative
stress
parameters
in
Eisenia
fetida
following
exposure
estradiol
soy
isoflavones,
resembling
concentrations
found
livestock
manure.
The
experiment
used
artificial
soil,
as
recommended
by
OECD
guidelines
(7:2:1
sand,
kaolin
peat).
Adult
specimens
were
randomly
divided
into
seven
groups
(n
=
11/replicate):
one
control,
three
(156.1,
283.4
633.8
μg/kg
dry
soil)
isoflavones
(113.0,
215.3
405.0
mg/kg
concentrations.
After
eight
weeks,
samples
collected
for
cytological,
histological
biochemical
analysis.
Offspring
development
was
after
12
additional
weeks.
Higher
isoflavone
led
lower
germ
cell
number
increased
abnormalities,
especially
seminal
vesicles
ovaries.
Catalase
peroxidase
activities
significantly
all
treated
groups.
did
not
E.
offspring.
These
findings
highlight
fetida's
EDCs
at
tissue
level,
suggesting
its
use
bioindicator
assessing
EDC
contamination
soils.
