Sensors,
Journal Year:
2024,
Volume and Issue:
24(12), P. 3744 - 3744
Published: June 8, 2024
To
monitor
the
biological
function
of
H2S
in
real
time,
this
investigation
demonstrated
design
and
synthesis
a
novel
fluorescent
probe
integrated
with
cyanine
2,4-dinitrophenol
for
qualitative
quantitative
detection
H2S.
An
NIR
sensitive
sensor
(FS-HS-1)
was
provided
straightforward
process.
Spectroscopy
experiments
elucidated
that
FS-HS-1
could
selectively
detect
PBS
solution
(containing
40%
acetonitrile)
111-fold
fluorescence
enhancement
at
715
nm
(ex.
605
nm).
The
response
towards
NaHS
occurred
less
than
2
min,
limit
confirmed
to
be
as
low
4.47
±
0.11
nmol/L.
Furthermore,
is
capable
monitoring
changes
exogenous
concentrations
within
living
cells
confocal
2P
imaging.
Analytical Letters,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 14
Published: March 27, 2024
Herein,
a
fluorescent
probe
BFO-HPS
was
developed
for
imaging
the
H2Sn
dynamics
of
macrophage
inflammatory
regulation
in
bone
homeostasis.
The
indicated
advantages
including
large
response
scale,
rapid
response,
steady
optical
performance
various
pH
conditions,
high
selectivity,
and
good
selectivity.
showed
dose-dependent
fluorescence
at
570
nm
concentration
with
linear
range
from
0.1
to
100
µM,
limit
detection
0.11
quantitation
0.10
µM.
Based
on
low
cyto-toxicity,
provided
intracellular
monitoring
exogenous
level
uninduced
RAW264.7
cells.
In
receptor
activator
nuclear
factor-κB
ligand
(RANKL)-induced
RANKL-induced
inhibited
groups,
achieved
indicate
macrophage-involved
This
work
informative
further
investigations