Critical review: Grand challenges in assessing the adverse effects of contaminants of emerging concern on aquatic food webs

Environmental Toxicology and Chemistry, Journal Year: 2018, Volume and Issue: 38(1), P. 46 - 60

Published: Oct. 8, 2018

Much progress has been made in the past few decades understanding sources, transport, fate, and biological effects of contaminants emerging concern (CECs) aquatic ecosystems. Despite these advancements, significant obstacles still prevent comprehensive assessments environmental risks associated with presence CECs. Many center around extrapolation single chemicals observed laboratory or found individual organisms species field to impacts multiple stressors on food webs. In present review, we identify 5 challenges that must be addressed promote studies CECs from singular exposure events multispecies web interactions. There needs be: 1) more detailed information complexity mixtures environment, 2) a greater sublethal wide range organisms, 3) an ascertaining consequences variable duration CEC exposures within across generations species, 4) linkage systems, 5) documenting trophic We examine current literature show how can fill knowledge gaps. Environ Toxicol Chem 2019;38:46-60. © 2018 SETAC.

Language: Английский

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Organic contaminants in Great Lakes tributaries: Prevalence and potential aquatic toxicity

The Science of The Total Environment, Journal Year: 2016, Volume and Issue: 554-555, P. 42 - 52

Published: March 4, 2016

Organic compounds used in agriculture, industry, and households make their way into surface waters through runoff, leaking septic-conveyance systems, regulated unregulated discharges, combined sewer overflows, among other sources. Concentrations of these organic waste (OWCs) some Great Lakes tributaries indicate a high potential for adverse impacts on aquatic organisms. During 2010-13, 709 water samples were collected at 57 tributaries, together representing approximately 41% the total inflow to lakes. Samples during runoff low-flow conditions analyzed 69 OWCs, including herbicides, insecticides, polycyclic aromatic hydrocarbons, plasticizers, antioxidants, detergent metabolites, fire retardants, non-prescription human drugs, flavors/fragrances, dyes. Urban-related land cover characteristics most important explanatory variables concentrations many OWCs. Compared from nonurban watersheds (<15% urban cover) (>15% had nearly four times number detected sample concentration, average. Concentration differences between not observed, but seasonal observed atrazine, metolachlor, DEET, HHCB concentrations. Water quality benchmarks individual OWCs exceeded 20 sites, 7 sites by factor 10 or more. The with frequent benchmark exceedances PAHs benzo[a]pyrene, pyrene, fluoranthene, anthracene, metabolite 4-nonylphenol, herbicide atrazine. Computed estradiol equivalency quotients (EEQs) using only nonsteroidal endocrine-active indicated medium risk estrogenic effects (intersex vitellogenin induction) sites. EEQs 3 comparable values reported effluent. This multifaceted study is largest, comprehensive assessment occurrence Basin date.

Language: Английский

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Bisphenol A in the environment and recent advances in biodegradation by fungi

Chemosphere, Journal Year: 2022, Volume and Issue: 303, P. 134940 - 134940

Published: May 16, 2022

Language: Английский

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Growth Retardation, Oxidative Stress, Immunosuppression, and Inflammatory Disturbances Induced by Herbicide Exposure of Catfish, Clarias gariepinus, and the Alleviation Effect of Dietary Wormwood, Artemisia cina

Fishes, Journal Year: 2023, Volume and Issue: 8(6), P. 297 - 297

Published: June 1, 2023

The present study evaluated the impact of chronic herbicide (oxyfluorfen; OXY) exposure on catfish, Clarias gariepinus, in terms growth, hematobiochemical parameters, immune response, antioxidant- and immune-related gene expression, resistance to monogenean parasites, Quadriacanthus aegypticus. In addition, protective role Wormwood, Artemisia cina (AC) against OXY through diet inclusion was also analyzed. catfish fingerlings were exposed (1.16 mg/L) for 60 days fed diets without AC supplementation (control) with 5% supplementation. results demonstrated that stunted growth; decreased survival, erythrograms leukograms, serum protein, acetylcholinesterase; negatively altered antioxidant status. On contrary, significantly reduced OXY’s negative impacts growth hematological, biochemical, balance. markedly increased levels biomarkers hepatorenal damage, stress indicators, DNA which alleviated induced immunosuppression manifested by a decrease lysozyme activities, complement c3, nitric oxide levels, phagocytic activity. Furthermore, regulated expression immune-antioxidant genes (CAT, GPX1, SOD1, GST, TGF-Β1). However, it upregulated CYP1a, IL-1β, TNF-α liver, anterior kidney, intestine C. gariepinus. Meanwhile, addition OXY-exposed fish notably restored components remedied expressions. Likewise, OXY-induced reduction survival rate after Q. aegypticus challenge. Accordingly, dietary could alleviate performance, physiological status, some immune-antioxidant-related expression.

Language: Английский

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Comprehensive Analysis of the Great Lakes Top Predator Fish for Novel Halogenated Organic Contaminants by GC×GC-HR-ToF Mass Spectrometry

Environmental Science & Technology, Journal Year: 2018, Volume and Issue: 52(5), P. 2909 - 2917

Published: Jan. 27, 2018

The U.S. Environmental Protection Agency's Great Lakes Fish Monitoring and Surveillance Program (GLFMSP) has traced the fate transport of anthropogenic chemicals in region for decades. Isolating identifying halogenated species fish is a major challenge due to complexity biological matrix. A nontargeted screening methodology was developed applied lake trout using 2-dimensional gas chromatograph coupled high resolution time-of-flight mass spectrometer (GC×GC-HR-ToF MS). Halogenated were identified combination authentic standards library spectral matching, with molecular formula estimations provided by exact interpretation. In addition currently being targeted GLFMSP, more than 60 identified. Most appear be metabolites or breakdown products larger organics. most abundant compound class halomethoxyphenols accounting 60% total concentration compounds top predator from all five illustrating need utility aquatic systems this platform.

Language: Английский

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Assessment of hematological, hepato-renal, antioxidant, and hormonal responses of Clarias gariepinus exposed to sub-lethal concentrations of oxyfluorfen

Aquatic Toxicology, Journal Year: 2019, Volume and Issue: 217, P. 105329 - 105329

Published: Oct. 12, 2019

Language: Английский

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Determination of endocrine disrupting compounds in fish liver, brain, and muscle using focused ultrasound solid–liquid extraction and dispersive solid phase extraction as clean-up strategy

Analytical and Bioanalytical Chemistry, Journal Year: 2016, Volume and Issue: 408(21), P. 5689 - 5700

Published: June 24, 2016

Language: Английский

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How do measured PBDE and HCBD levels in river fish compare to the European Environmental Quality Standards?

Environmental Research, Journal Year: 2017, Volume and Issue: 160, P. 203 - 211

Published: Oct. 11, 2017

This study evaluates the current situation regarding PBDE and HBCD levels in different river fish species. We collected published data last five years countries around world. These of pollution were compared with Environmental Quality Standards (EQS) for biota established by European Directive field water policy. Although is not critical, only some values exceeding limit about 5 times, clearly exceeded EQS, 25% samples up to ten thousand times. it expected that PBDEs will decrease over next due ban their use, this reach EQS end 2021, as demanded Directive. Hence, necessary implement new strategies order minimize impact on environment.

Language: Английский

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Recent advances and open questions around pesticide dynamics and effects on freshwater fishes

Current Opinion in Environmental Science & Health, Journal Year: 2018, Volume and Issue: 4, P. 38 - 44

Published: Aug. 1, 2018

Language: Английский

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Moringa oleifera and Azadirachta indica Leaves Enriched Diets Mitigate Chronic Oxyfluorfen Toxicity Induced Immunosuppression through Disruption of Pro/Anti-Inflammatory Gene Pathways, Alteration of Antioxidant Gene Expression, and Histopathological Alteration in Oreochromis niloticus

Fishes, Journal Year: 2022, Volume and Issue: 8(1), P. 15 - 15

Published: Dec. 26, 2022

Our goal in this study was to determine the effect of dietary supplementation with Moringa oleifera (M. oleifera), and Azadirachta indica (A. indica) leaves mitigating effects chronic oxyfluorfen (OXY) toxicity on health status, expressions immune antioxidant genes, tissue morphological alterations Oreochromis niloticus. In study, we used 370 healthy O. niloticus (average weight = 25.35 ± 0.29 g). We 70 fish 96 h lethal concentration 50 (LC50) OXY. assigned another 300 into six equal groups five replicates (50 fish/group, 10 fish/replicate) OXY for 60 days. The LC50 6.685 mg/L. Exposure 1/10 (0.668 mg/L) had impacts pathological changes main tissues. addition, oxidant genes were disrupted. Dietary both M. A. efficiently mitigated toxic treated groups. Comparing palliative efficiency indica, results showed that more potent alleviating

Language: Английский

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