Environmental Pollution,
Journal Year:
2023,
Volume and Issue:
331, P. 121878 - 121878
Published: May 25, 2023
The
lack
of
data
on
the
chronic
effects
chloroacetanilide
herbicide
metabolites
non-target
aquatic
organisms
creates
a
gap
in
knowledge
about
comprehensive
impacts
excessive
and
repeated
pesticide
use.
Therefore,
this
study
evaluates
long-term
propachlor
ethanolic
sulfonic
acid
(PROP-ESA)
after
10
(T1)
20
(T2)
days
at
environmental
level
3.5
μg.L−1
(E1)
its
10x
fold
multiply
35
(E2)
model
organism
Mytilus
galloprovincialis.
To
end,
PROP-ESA
usually
showed
time-
dose-dependent
trend,
especially
amount
soft
mussel
tissue.
bioconcentration
factor
increased
from
T1
to
T2
both
exposure
groups
–
2.12
5.30
E1
2.32
5.48
E2.
Biochemical
haemolymph
profile
haemocyte
viability
were
not
affected
by
exposure.
In
addition,
digestive
gland
(DG)
cells
decreased
only
E2
compared
control
T1.
Moreover,
malondialdehyde
levels
gills,
DG,
superoxidase
dismutase
activity
oxidatively
modified
proteins
PROP-ESA.
Histopathological
observation
several
damages
gills
(e.g.,
vacuolation,
over-production
mucus,
loss
cilia)
DG
growing
trend
infiltrations,
alterations
tubules).
This
revealed
potential
risk
herbicide,
propachlor,
via
primary
metabolite
Bivalve
bioindicator
species
M.
Furthermore,
considering
possibility
biomagnification
effect,
most
prominent
threat
poses
ability
be
accumulated
edible
tissues.
future
research
toxicity
alone
or
their
mixtures
is
needed
gain
results
living
organisms.
Environmental Technology & Innovation,
Journal Year:
2021,
Volume and Issue:
25, P. 102122 - 102122
Published: Nov. 27, 2021
Triclosan
(TCS),
a
lipophilic
broad-spectrum
biocide
is
widely
used
in
personal
care,
acrylic,
veterinary,
medical
and
household
products.
It
has
been
observed
to
be
present
aquatic
environments,
animal
plant
tissues
around
the
world,
even
human
blood,
urine
breast
milk.
Under
natural
conditions,
TCS
degrades
photolytically
as
well
through
microbial
action
into
more
persistent
toxic
byproducts
like
dioxins.
Moreover,
accumulation
deep
water
bodies
or
soil
strata
where
light
not
adequately
available
makes
its
degradation
prolonged.
Present
review
undertaken
with
an
objective
highlight
concerns
surrounding
exposure
organisms,
infiltration
routes
food
chain,
persistence
accumulation,
teratogenic,
biochemical
cytogenic
effects
on
wide
range
of
species.
The
widespread
use
products
containing
potential
toxicity
at
lethal
concentrations
it
compound
utmost
concern
worldwide
hence
under
permissible
levels,
proper
disposal
needs
regulated.
Frontiers in Physiology,
Journal Year:
2023,
Volume and Issue:
14
Published: June 26, 2023
Microplastics
and
pesticides
are
emerging
contaminants
in
the
marine
biota,
which
cause
many
harmful
effects
on
aquatic
organisms,
especially
fish.
Fish
is
a
staple
affordable
food
source,
rich
animal
protein,
along
with
various
vitamins,
essential
amino
acids,
minerals.
Exposure
of
fish
to
microplastics,
pesticides,
nanoparticles
generates
ROS
induces
oxidative
stress,
inflammation,
immunotoxicity,
genotoxicity,
DNA
damage
alters
gut
microbiota,
thus
reducing
growth
quality
Changes
behavioral
patterns,
swimming,
feeding
habits
were
also
observed
under
exposures
above
contaminants.
These
affect
Nrf-2,
JNK,
ERK,
NF-κB,
MAPK
signaling
pathways.
And
Nrf2-KEAP1
signalling
modulates
redox
status
marinating
enzymes
Effects
found
modulate
antioxidant
enzymes,
including
superoxide
dismutase,
catalase,
glutathione
system.
So,
protect
health
from
contribution
nano-technology
or
nano-formulations
was
researched.
A
decrease
nutritional
population
significantly
impacts
human
diet,
influencing
traditions
economics
worldwide.
On
other
hand,
traces
microplastics
habitat
water
can
enter
humans
by
consuming
contaminated
may
result
serious
hazards.
This
review
summarizes
stress
caused
due
nano-particle
contamination
exposure
their
impact
health.
As
rescue
mechanism,
use
management
disease
discussed.
Environmental Toxicology and Pharmacology,
Journal Year:
2023,
Volume and Issue:
98, P. 104068 - 104068
Published: Jan. 19, 2023
Microplastic
(MP)
and
heating
(T)
suspected
to
modulate
biological
effects
of
aquatic
contaminants.
Salinomycin
(Sal)
is
veterinary
antibiotic
anticancer
agent.
The
goal
this
study
was
examine
the
multistress
effect
MP,
Sal
T
on
bioindicator
bivalve
mollusc.
Unio
tumidus
were
treated
with
MP
(1
mg
L-1),
(0.6
µg
their
combination
under
18°
C
(Mix)
25°
(MixT)
for
14
days.
digestive
glands
analyzed.
did
not
cause
changes
Mn-
Cu,Zn-SOD,
lipid
peroxidation
Cyp-450-depended
EROD
levels,
whereas
catalase,
GST
protein
carbonyls
(Sal-group)
increased
compared
control.
In
Mix-group,
enzymes,
particularly
(by
34%
115%
respectively)
up-regulated.
However,
in
MixT-group,
they
corresponding
control
or
lesser
(EROD,
catalase).
Our
findings
emphasize
need
take
into
account
interactions
environmental
risk
assessment.
Journal of Marine Science and Engineering,
Journal Year:
2020,
Volume and Issue:
8(2), P. 73 - 73
Published: Jan. 23, 2020
Deltamethrin
is
responsible
for
health
and
reproduction
problems
both
in
mammals
aquatic
organisms.
In
this
study,
zebrafish
adults
were
exposed
15
days
to
0.25,
0.5,
1,
2
μg
L−1
non-lethal
concentrations
of
deltamethrin,
knowing
that
used
worldwide
on
agricultural
crops.
We
investigated
the
chronic
effects
deltamethrin
gonads
by
histopathological
examination,
immunohistochemistry,
immunofluorescence
using
biomarkers
apoptosis
(anti-p53,
anti-H2A.XS139ph
antibodies,
TUNEL
assay),
oxidative
stress
(anti-Cox4i1
antibody)
proliferation
(anti-PCNA
antibody).
Among
changes,
apoptotic
response
was
elevated
ovary
testis
groups
as
it
seen
IHC
IF
p53,
H2A.XS139ph,
confirmed
assay.
These
observed
case
all
studied
compared
with
control
group.
Thereby,
gonadal
tissue
exhibited
an
up-regulated
activity
cell-death
signaling
markers,
while
marker
(PCNA)
increased
due
its
presence
not
only
primary
growth
cortical-alveolar
stage
follicles
but
also
atretic
follicles,
meanwhile
decreased
notably
testis.
Cox4i1,
a
mitochondrial
marker,
during
treatment,
probably
inhibited
overproduction
free
radicals
after
pesticide
exposure.
