Toxicity of water-soluble polymers polyethylene glycol and polyvinyl alcohol for fish and frog embryos DOI Creative Commons
Giorgia Zicarelli, Caterina Faggio, Jana Blahová

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 933, P. 173154 - 173154

Published: May 10, 2024

Personal Care Products (PCPs) have been one of the most studied chemicals in last twenty years since they were identified as pseudo-persistent pollutants by European Union early 2000s. The accumulation PCPs aquatic environment and their effects on non-target species make it necessary to find new, less harmful, substances. Polyethylene glycol (PEGs) polyvinyl alcohol (PVAs) are two polymers that increased presence composition recent years, but little is known about effect species. Through embryotoxicity tests common models organisms (Danio rerio Xenopus laevis), this work aims increase knowledge PEGs PVAs' Animals exposed pollutant for 96 h. main endpoint (mortality, hatching, malformations, heartbeat rate) was recorded every 24 significant results hatching delay Danio both chemicals, malformations (oedema, body changes pigmentation deformations spine tail) D. X. laevis change rate (decrease or animals all tested.

Language: Английский

Nanopesticides in agricultural pest management and their environmental risks: a review DOI

Kannan Maharajan,

N. Bojan,

J. Swaminathan

et al.

International Journal of Environmental Science and Technology, Journal Year: 2023, Volume and Issue: 20(9), P. 10507 - 10532

Published: Feb. 7, 2023

Language: Английский

Citations

74
Single and combined effects of CuSO4 and polyethylene microplastics on biochemical endpoints and physiological impacts on the narrow-clawed crayfish Pontastacus leptodactylus DOI Creative Commons
Amir Zeidi, Mohammad Hossein Sayadi,

Mohammad Reza Rezaei

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 345, P. 140478 - 140478

Published: Oct. 19, 2023

This study investigated the toxicity of polyethylene microplastics (MPs; <0.02 mm) and CuSO4, alone in combination, on freshwater crayfish Pontastacus leptodactylus. In this study, were exposed to PE-MPs (0.0, 0.5, 1 mg L-1) CuSO4·5H2O for a period 28 days. Next, multi-biomarkers, including biochemical, immunological, oxidative stress indicators analyzed. Results showed that co-exposure CuSO4 resulted increased aspartate aminotransferase (AST), alanine (ALT), lactate dehydrogenase (LDH), decreased alkaline phosphatase (ALP), butyrylcholinesterase (BChE), gamma-glutamyl-transferase (GGT). Triglycerides, cholesterol, glucose, albumin content also increased. Although no significant change was observed lysozyme phenoloxidase activities co-exposed 0.5 L-1 MPs their significantly other experimental groups. Oxidative parameters hepatopancreas indicated superoxide dismutase (SOD), glutathione peroxidase (GPx), malondialdehyde (MDA) levels, but catalase (CAT), glucose 6-phosphate (G6PDH), cellular total antioxidant (TAC). sub-chronic confirmed. The confirmed found higher concentrations led more severe effects. Co-exposure primarily compromised endpoints, showing when both pollutants present concentrations. POX, LYZ, ALP, GGT, LDH, CAT suppressed by MPs. However, synergistic increase measured biomarkers

Language: Английский

Citations

45
Evaluating quaternium-15 effects on Mytilus galloprovincialis: New insights on physiological and cellular responses DOI Creative Commons
Federica Impellitteri,

Kristian Riolo,

Cristiana Roberta Multisanti

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 918, P. 170568 - 170568

Published: Feb. 2, 2024

Among personal care products, quaternium-15 is prominently featured as a preservative in items such shampoos, soaps, shaving and cosmetics. The widespread use of these products people's daily routines contributes to release into aquatic ecosystems. In this context, the primary aim study was assess physiological cellular responses digestive gland gills Mytilus galloprovincialis exposure. Cell viability ability cells regulate their volume were evaluated. Additionally, expression genes involved oxidative stress response assessed further substantiate compound's harmful effects. Results indicated significant decrease both RVD (regulatory decrease) capacity when exposed hypotonic solution. Furthermore, impairment cell function corroborated by modulation stress-related gene expression, including SOD, Cat, well Hsp70 CYP4Y1. Similar alterations observed gills, reflecting impaired functionality vital organ well. summary, outcomes provide conclusive evidence toxicity quaternium-15. This underscores urgent need investigate toxicological effects contaminant on ecosystems emphasises necessity limiting containing

Language: Английский

Citations

18
Oregano (Origanum vulgare) Extract Enhances Zebrafish (Danio rerio) Growth Performance, Serum and Mucus Innate Immune Responses and Resistance against Aeromonas hydrophila Challenge DOI Creative Commons
Ghasem Rashidian,

Javad Tahmasebi Boldaji,

Simona Rainis

et al.

Animals, Journal Year: 2021, Volume and Issue: 11(2), P. 299 - 299

Published: Jan. 25, 2021

This study evaluated the dietary effects of an ultrasound-assisted extract

Language: Английский

Citations

93
Lycopene reduces the impacts of aquatic environmental pollutants and physical stressors in fish DOI
Mahmoud A.O. Dawood, Mohsen Abdel‐Tawwab, Hany M.R. Abdel‐Latif

et al.

Reviews in Aquaculture, Journal Year: 2020, Volume and Issue: 12(4), P. 2511 - 2526

Published: June 18, 2020

Abstract Aquatic organisms are susceptible throughout their lives to chemical and physical stressors, which negatively affect health. Various aquatic pollutants derived from industrial effluents, overuse of some agricultural pesticides, herbicides insecticides may cause devastating toxicological aspects deteriorate health growth. They also led oxidative stress fish due the stimulation production reactive oxygen species. Therefore, need for using natural antioxidants be used as feed additives is great importance counteract hazardous responses. The use phytochemicals, characterized by substantial antioxidative effects, has been raised. Lycopene principal carotenoid pigment found in tomatoes products, vegetables red fruits. Numerous studies have recommended lycopene a powerful antioxidant attenuate responses several species exposed various toxicants or any other conditions. maintains condition enhancing immune This review article aimed elucidate current information about potential dietary its capability haemato‐immunological alterations resulted environmental stressors. Additionally, discusses regarding mode action assess profits that would aquaculture industry.

Language: Английский

Citations

77
Difenoconazole induces cardiovascular toxicity through oxidative stress-mediated apoptosis in early life stages of zebrafish (Danio rerio) DOI Creative Commons
Jiansheng Zhu, Chunlan Liu, Jingyu Wang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2021, Volume and Issue: 216, P. 112227 - 112227

Published: April 11, 2021

Difenoconazole (DIF), a common broad-spectrum triazole fungicide, is associated with an increased risk of cardiovascular diseases. Unfortunately, little attention has been paid to the mechanisms underlying this association. In study, zebrafish embryos were exposed DIF (0, 0.3, 0.6 and 1.2 mg/L) from 4 96 h post fertilization (hpf) toxicity was evaluated. Our results showed that decreased hatching rate, survival rate heart malformation rate. Cardiovascular deformities are most prominent, including pericardial edema, abnormal cardiac structure disrupted vascular pattern in two transgenic models (myl7:egfp fli1:egfp). exacerbated oxidative stress by via accumulation reactive oxygen species (ROS) inhibition antioxidant enzyme. apoptosis triggered through expression p53, bcl-2, bax caspase 9, while suppressed transcription key genes involved calcium signaling muscle contraction. These adverse outcomes restored N-acetyl-L-cysteine (NAC), indicating played crucial role DIF-induced caused Taken together, study revealed provided novel insights into strategies mitigate its toxicity.

Language: Английский

Citations

60
Impact of pharmaceutical products on zebrafish: An effective tool to assess aquatic pollution DOI
Miriam Porretti, Federica Arrigo, Giuseppa Di Bella

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2022, Volume and Issue: 261, P. 109439 - 109439

Published: Aug. 9, 2022

Language: Английский

Citations

53
Antioxidant enzyme activity and pathophysiological responses in the freshwater walking catfish, Clarias batrachus Linn under sub-chronic and chronic exposures to the neonicotinoid, Thiamethoxam® DOI
Dip Mukherjee, Shubhajit Saha, Azubuike V. Chukwuka

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 836, P. 155716 - 155716

Published: May 5, 2022

Language: Английский

Citations

51
Ecotoxicological Effects of Pesticides on Hematological Parameters and Oxidative Enzymes in Freshwater Catfish, Mystus keletius DOI Open Access

Ayyanar Barathinivas,

S. Ramya,

Kooturan Neethirajan

et al.

Sustainability, Journal Year: 2022, Volume and Issue: 14(15), P. 9529 - 9529

Published: Aug. 3, 2022

Hematological parameters and changes in stress-induced functionalities of cellular enzymes have been recognized as valuable tools for monitoring fish health determining the toxic effects pesticides. The present study was conducted to evaluate effect selected pesticides viz., Ekalux (EC-25%), Impala (EC-55%), Neemstar (EC-15%) on freshwater catfish Mystus keletius. Fish were exposed sub-lethal concentrations (mg/L) pesticide a period 7, 14, 21, 28 days. total erythrocyte (RBC), hemoglobin (Hb), hematocrit (Ht) packed cell volume values decreased with an increase exposure time pesticides, whereas leucocytes (WBC), mean corpuscular concentration (MCHC), (MCV), (MCH) increased significantly. A decrease (PCV) coupled deformed erythrocytes signs anemia also observed. RBC content 1.43 (million/mm3) day 7 reduced 1.18 days 14 21. similar trend found RBC, which had initial value 1.36 reached 1.10 28. In contrast, from 1.59 control 1.02 Data indicates that order recorded maximum followed by model. Likewise, overall pattern pesticidal activity (GDH, MDH, SDH) Neemstar. Results indicate Chlorpyrifos pesticide-Impala evoked tissues compared other two tested. Statistical analysis summative data using way ANOVA statistically significant (p-value < 0.001). differences hematological analyzed are attributed physiological acclimatization local conditions, influences energy metabolism consequently determines status fish. Overall, exhibited highest enzyme, suggest natural may be preferable rice field application terms environmental safety.

Language: Английский

Citations

50
Long-term exposure to small-sized silica nanoparticles (SiO2-NPs) induces oxidative stress and impairs reproductive performance in adult zebrafish (Danio rerio) DOI
Ghasem Rashidian,

Ramin Mohammadi-Aloucheh,

Farnaz Hosseinzadeh Otaghvari

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2023, Volume and Issue: 273, P. 109715 - 109715

Published: Aug. 16, 2023

Language: Английский

Citations

29